History Main / GenderFlip

* Plum Pudding in the original ''WesternAnimation/StrawberryShortcake'' line was originally a boy, "he" was later reintroduced to the line as a "she".

* The three ''VisualNovel/TokimekiMemorialGirlsSide'' games. The UsefulNotes/NintendoDS ports of the first two ''Girl's Side'' games also have complete fan translations.

** The ''VideoGame/Persona3'' VideogameRemake for the [[UsefulNotes/PlayStationPortable PSP]], you can play as a female protagonist. While she herself averts this trope - not only does she have a [[GenkiGirl drastically]] [[TheHeart different]] personality from her [[TheEeyore male]] [[SugarAndIcePersonality counterpart]], she also has her own set of [[RelationshipValues Social Links]] - her Initial Persona is a feminized version of [[Myth/ClassicalMythology Orpheus]], which is the same Persona as the male's. [[TroublingUnchildlikeBehavior Ken Amada's]] Initial Persona, meanwhile, is the female Nemesis, but due to its [[https://vignette.wikia.nocookie.net/megamitensei/images/e/e3/Nemesis.png/revision/latest?cb=20161019072510 oddly toyetic appearance]], it comes off as more gender neutral.

* The ''Pia Carrot'' HGame series had male main characters and a group of female love interests in its four NumberedSequels and spinoffs. Then a reverse harem story called ''Prince Pia Carrot'' was released on UsefulNotes/PlaystationPortable in October 2014 with just a [[UsefulNotes/MediaClassifications CERO D]] rating.

* ''[[https://archiveofourown.org/works/52809949/chapters/133573888 I Ain't A Doll, This Ain't a Dollhouse]]'': The premise is that the story is an adaptation of ''VideoGame/JoJosBizarreAdventureEyesOfHeaven'' with [[Manga/JoJosBizarreAdventurePhantomBlood Jonathan Joestar]] both [[AscendedExtra having a larger role in the narrative]] ''and'' as a woman named Johanna Joestar. Additionally, Jonathan's LoveInterest Erina Pendleton is now a man named Erin.

* In the original [[UsefulNotes/TheBronzeAgeOfComicBooks Bronze Age]] continuity (and, apparently, in the "Post-Zero Hour" continuity), the ComicBook/LegionOfSuperHeroes' [[TheCommissionerGordon Science Police liaison]] Shvaughn Erin was a woman. The "Five Years Later" continuity retconned her into being a UsefulNotes/{{transgender}} person named ''Sean'' Erin, who stopped using [[AdvancedPhlebotinum Pro-Fem]] when he realised Element Lad was actually gay.

** The Thor Corps consists of various versions of [[ComicBook/TheMightyThor Thor]] from across the Multiverse, including female wielders of Mjolnir like ComicBook/{{Storm}}, ComicBook/{{Gamora}}, ComicBook/{{Dazzler}} and [[ComicBook/{{SHIELD}} Maria Hill]].

* ''Fanfic/SpiderNinja'' takes place not only in a part of the Spiderverse where the [[Franchise/TeenageMutantNinjaTurtles TMNT]] exist, but where Peter Parker was born a girl (known as Petra Parker[[spoiler:[[AdoptiveNameChange -Hamato]]]]).

** One of the major characters is Aquawoman, the ComicBook/{{Aquaman}} analog of Earth-11. Earth-11 is later explored in further detail in ''Teen Justice'', an iteration of the Comicbook/TeenTitans starring Comicbook/{{Robin}} (a female version of Damian Wayne named Talia Kane), Supergirl (a female version of [[Characters/SupermanJonathanSamuelKent Jon Kent]] named Laurel Lane), Troy (a male version of [[Comicbook/WonderGirl Donna Troy]] named Donald Troy), Aquagirl (a female version of Jackson Hyde named Jacqui Hyde), Klarienne the Witch-Girl (a female version of Comicbook/KlarionTheWitchBoy), a male version of Comicbook/{{Raven}}, and Kid Quick (a gender fluid version of Kid Flash named Jess Chambers).

* Overlapping with CanonCharacterAllAlong, the comic book sequel to ''Comicbook/MegaManFullyCharged'' reveals that Mega Man's adoptive sister Suna is that continuity's version of Zero.

** Subsequent ''Spider-Verse'' stories, such as ''Comicbook/EdgeOfSpiderVerse2022'' introduce even more gender flips and {{Distaff Counterpart}}s, including Zarina Zahari (Spider-UK), Charlie Webber (Sun-Spider) and Hida Haruka (Sakura Spider). There's also the Disney Princess-inspired Princess Petra, a.k.a. Spinstress, whose love interest is a male Comicbook/MaryJaneWatson known as "Merry" James Watson, and whose enemy is a female version of Mysterio known as the Mysterious Empress. Even her FairyGodmother is "[[Comicbook/NormanOsborn Norma the Fairy Gob-Mother]]."

* The ''Comicbook/{{Grandville}}'' RPG gives Chance Lucas, the CaptainErsatz of Comicbook/LuckyLuke from ''Grandville: Noel'', a mare named Jolie as his detective partner; a gender flipped (and {{Anthropomorphic Shift}}ed) Jolly Jumper.

* Technically all games where you can pick the gender of your PlayerCharacter feature gender flipped versions of the protagonist. No matter if you play as male or female, your character is given the same backstory, same quests, and same character arc. A good example is Creator/BioWare's ''Franchise/MassEffect'' trilogy, where Shepard is given the same last name, familial backstory, and pre-service record regardless of gender, so the male and female versions of Shepard are essentially Gender Flipped alternate versions of each other. Some games, however, like ''VideoGame/Fallout4'', avert this by making the male and female versions of the PlayerCharacter distinct. In the case of ''Fallout 4'', the male and female versions of the Sole Survivor are husband and wife, the latter a retired military veteran, and the former an out-of-practice lawyer and stay-at-home mother. [[spoiler:The PC of the chosen gender is the only one to survive the prologue and a main part of the character's motivation through the story is finding the one who kidnapped their son and killed their spouse.]]

* Technically all games where you can pick the gender of your PlayerCharacter feature gender flipped versions of the protagonist. No matter if you play as male or female, your character is given the same backstory, same quests, and same character arc. A good example is Creator/BioWare's ''Franchise/MassEffect'' trilogy, where Shepard is given the same last name, familial backstory, and pre-service record regardless of gender, so the male and female versions of Shepard are essentially Gender Flipped alternate versions of each other. Some games, however, like ''VideoGame/Fallout4'', avert this by making the male and female versions of the PlayerCharacter distinct. In the case of ''Fallout 4'', the male and female versions of the Sole Survivor are husband and wife. [[spoiler:Only the chosen PC survives the tutorial, and part of their motivation is tracking down their spouse's killer.]]

* ''Musketeer Space'' is another gender-flipped ''Literature/TheThreeMusketeers'' (with the exception of Athos, for some reason), literally [[RecycledInSpace Recycled IN SPACE!]]. D'Artagnan becomes Dana, mysterious assassin Milady de Winter becomes [[spoiler:alien spy]] Milord de Winter, etc. And [[EthicalSlut Aramis]] continues to sleep with every woman around.

* Done InUniverse in ''ComicBook/AngelIDW''. There was a Hollywood movie (VeryLooselyBasedOnATrueStory) about The Fall, which had [[http://images.wikia.com/buffy/images/5/55/SheSpike.jpg Spike as a woman.]] [[note]]Technically it's a CompositeCharacter of Spike and Darla, but for all intents and purposes it's Spike as a woman. And yes, before you ask, fem-Spike gets pregnant.[[/note]] When they watched it, Angel was disgusted and insulted, while Spike thought it was hilarious.

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* GenderFlip/LiveActionTV

!!Examples with their own page:

!!Examples:

[[folder:Films — Live-Action]]
* The 2018 film ''The Adventures of Thomasina Sawyer'' is an adaptation of ''Literature/TheAdventuresOfTomSawyer'' in which ... well, the title says it all, really.
* In the film adaptation of the comic ''ComicBook/{{Alena}}'' Fabian becomes Fabienne.
* Warrant Officer [[Characters/AlienMain Ripley]] from the first film in the ''Film/{{Alien}}'' franchise. It's a telling point in the ''SlidingScaleOfGenderInequality'' that the first iconic badass ''ActionGirl'' role was actually [[https://www.cbr.com/alien-ridley-scott-ripley-role-changed-male-female/ originally written as a man.]]
* ''Film/AllTheTroublesOfTheWorld'': Corrections officer Ali Othrnan is changed to a female character and [[AdaptationNameChange renamed Barbara Hammond]].
* Dr. Kafka, the [[BedlamHouse Ravencroft Institute]]'s MadScientist in ''Film/TheAmazingSpiderMan2'', played by Marton Csokas, is a gender-flip (and AdaptationalVillainy) version of Dr. Ashley Kafka, the [[TheShrink Awesome Shrink]] who founded the Institute in the comics.
* Dr. Peter Leavitt is changed into Dr. ''Ruth'' Leavitt in the film adaptation of ''Film/TheAndromedaStrain''.
* Sandy the dog, (a male in the previous adaptations of ''Theatre/{{Annie}}'' as well as in ''ComicStrip/LittleOrphanAnnie''), is a female in ''Film/Annie2014''.
* The 2020 ''Literature/ArtemisFowl'' [[Film/ArtemisFowl movie]] turns the books' Commander Julius Root female, played by Dame Creator/JudiDench, no less.
* In the Creator/RussellBrand remake of ''Film/Arthur2011'', Hobson the butler, played by Sir Creator/JohnGielgud in the original, becomes Lillian Hobson the nanny, played by Dame Creator/HelenMirren. In addition, Arthur's mother takes the role his father had in the original.
* The 1967 version of ''Film/{{Bedazzled|1967}}'' starred Creator/PeterCook as the Devil. [[Film/Bedazzled2000 The 2000 remake]] cast Elizabeth Hurley in that role.
* ''Film/{{Burglar}}'' gender flipped several of the main characters, as well as giving a RaceLift to the protagonist. The movie was based on a series of novels by Lawrence Block about a white male bookstore owner/burglar. The screenplay was written after Creator/BruceWillis passed on the role and it became a vehicle for Whoopi Goldberg.
* Critics pointed out that much of ''Film/{{Byzantium}}'' is basically a gender-flipped take on Jordan's earlier film adaptation of ''Interview with the Vampire''.
* In the low-budget 1990 ''Film/{{Captain America|1990}}'' movie, Professor Erskine is reimagined as a female scientist named Maria Vaselli.
* In the 2019 [[Film/{{Cats}} film adaptation]] of ''Theatre/{{Cats}}'', Old Deuteronomy (who is male in the musical and the [[Literature/OldPossumsBookofPracticalCats source material]]) is played by actress Creator/JudiDench.
* There are far too many adaptations of ''Literature/AChristmasCarol'' with Ebenezer Scrooge replaced by a female with a similar backstory and attitude (but not necessarily the same age and attractiveness).
* Jaq the mouse from ''WesternAnimation/{{Cinderella}}'' becomes Jacqueline in ''Film/Cinderella2015''.
* The Jerry Lewis movie ''Film/{{Cinderfella}}'', as the title implies, is a Gender Flip of Literature/{{Cinderella}}, with a male Cinderella (played by Lewis, of course), a [[PrinceCharming Princess Charming]], a [[FairyGodmother fairy godfather]] played by Ed Wynn, and two stepbrothers (although the WickedStepmother remains female).
* ''Film/CocaineBear'': [[spoiler: The bear in the movie is female, while the real bear was male.]]
* ''Film/ColorOutOfSpace2020'' changes the Gardners' middle son from [[Literature/TheColourOutOfSpace the original short story]] into a daughter, Lavinia.
* A 1990s adaptation of Creator/MickeySpillane's ''Come Die With Me'' made Literature/MikeHammer's cop buddy Lt. Pat Chambers into ''Patricia'' Chambers.
* Creator/JessicaChastain's character in ''Film/DarkPhoenix'' is Vuk, a very obscure male alien who showed up back in ''ComicBook/TheAvengers'' #4 during TheSixties. However, as Vuk's form was [[KillAndReplace stolen from a human woman she murdered]], her original alien gender is unknown.
* In the American remake of ''Film/LesDiaboliques'', the male detective Finchet became Shirley Vogel, portrayed by Creator/KathyBates.
* ''Film/DollyDearest'': The film is basically a gender flip of ''Film/ChildsPlay'' with a girl and a female doll.
* With its virtually identical ClearMyName plotline, one could consider the Creator/AshleyJudd vehicle ''Film/DoubleJeopardy'' to be a Gender Flip of ''Film/TheFugitive''. Both movies even feature Creator/TommyLeeJones as a lawman who first hunts for, then aids, the fugitive. We even get a misleading 911 call made by the victim [[spoiler:though as the audience soon learns, this was deliberately done in order to ensure that the woman would be convicted]], as well as the protagonist wailing, "I didn't kill my husband!", similar to Richard Kimble. Indeed, not only was the movie referred to as ''The Female Fugitive'' by several critics, people genuinely needed to be informed that it was NOT another sequel.
* ''Film/{{Dune 2021}}'' reimagines Liet Kynes, a white man in the novel and [[Film/Dune1984 the 1984 film]] (where he was played by Creator/MaxVonSydow), as a [[RaceLift Black]] woman played by Sharon Duncan-Brewster.
* In the live-action adaptation of Creator/OrsonScottCard's ''Film/EndersGame'', the male character of Major Anderson is played by Viola Davis. Interestingly, they were originally going to have ''Graff'' played by a woman (an idea that met with Card's approval), but then Creator/HarrisonFord got the part, so they gender flipped Anderson instead.
* ''Film/EnolaHolmes2'' applies this to [[spoiler:Moriarty, who is in the film portrayed as a black woman played by Creator/SharonDuncanBrewster.]]
* ''Film/TheHustle'' is ''Film/DirtyRottenScoundrels'' with conwomen preying on men instead of conmen preying on women. The tagline "Giving Dirty Rotten Men a Run for Their Money" acknowledges this.
* ''Franchise/EvilDead''
** Conversely, Creator/BruceCampbell in ''Film/TheEvilDead1981'' plays what is essentially the FinalGirl of the horror movie. It wasn't planned that way, however. The order in which characters died was actually determined by actor availability. If an actor left early in the shoot, his or her character also died early in the movie. Apparently Campbell was the one without a life, though that seems to have worked to his benefit in the long run.
** In [[Film/EvilDead2013 the remake]][[spoiler: /StealthSequel]], Ash's role is filled by an {{Expy}} named Mia.
* This was done in both adaptations of the Literature/HerculePoirot story ''Evil Under the Sun'' by Creator/AgathaChristie:
** In the 1982 version, Emily Brewster becomes the flamboyant and effeminate Rex Brewster.
** In the 2001 version, the victim's teenaged stepdaughter Linda turns into a stepson Lionel.
* The film ''Film/EyeInTheSky'''s protagonist Colonel Powell was originally written to be a male. It was changed to a female, played by Helen Mirren.
* ''Film/FrightNight2NewBlood'' is supposedly a sequel to [[Film/FrightNight2011 the 2011 remake]] of [[Film/FrightNight1985 the 1985 movie]], but it's really just another remake with Jerry (renamed Gerri) as a female vampire. Oh, and [[JustForFun/RecycledInSpace it's set in Romania instead of the United States]].
* In the original ''Film/Ghostbusters1984'', the eponymous ghost-hunting team is made up of four men with a female secretary. In [[Film/Ghostbusters2016 the 2016 remake]], the team is all-female and their secretary is a man.
* The plot of ''Film/Grease2'' is basically a flip of the first movie's plot. The guy is now the naïve, sweet one and the girl is the tough, experienced gang member.
* In the ''Literature/HarryPotter'' books, every player on the Slytherin Quidditch team either has a male first name or is referred to only by their surname. In the first film, however, their Keeper (Miles Bletchley in the book) is replaced by a girl.
* Zig-zagged with ''Film/{{Hellraiser 2022}}''. This film's version of Pinhead, the Priest, is portrayed by a woman for the first time, which flips the precedent for the films but is more accurate to ''Literature/TheHellboundHeart'', as in the novella "Pinhead" was an ambiguously-gendered Cenobite whose only clue to their gender was a feminine voice.
* Double subverted in the short film ''Film/HighAndTight'' where the third Olsen sibling was first a boy called Seth - then changed to a girl called Serena. Then when the original actress dropped out and no replacements could be found in time, the character became a boy again.
* ''Film/HeadOverHeels2001'' is a gender-flipped romantic comedy version of ''Film/RearWindow''.
* The Creator/HowardHawks classic newspaper comedy ''Film/HisGirlFriday'' is a gender-flipped version of the play ''The Front Page'' (which had already been made into an acclaimed movie once before). Hawks turned the "Hildy Johnson" character into a woman and made it a romantic comedy. Creator/BillyWilder later remade it yet again with two male protagonists, and then an '80s remake called ''Switching Channels'' - set this time in the television news industry - put the romance aspect back.
* In a WhatCouldHaveBeen example, when ''Film/DonnieDarko'' director Richard Kelly was offered the chance to helm a film adaptation of Louis Sachar's ''Literature/{{Holes}}'', his screenplay for the movie changed the female warden of Camp Green Lake (real name [[GenderBlenderName Lou Walker]]) to an unnamed man--among many, ''many'' other changes [[InNameOnly that left the story almost unrecognizable]].
* The MadeForTVMovie ''How to Marry a Billionaire'' is a SettingUpdate of ''Film/HowToMarryAMillionaire'', except it's about three men looking for rich wives.
* The ''Film/JemAndTheHolograms2015'' movie sees Eric Raymond from ''WesternAnimation/{{Jem}}'' turned into a woman (Eric'''a'''). [[spoiler:She's also Rio's mother]].
* In both Disney's [[Film/TheJungleBook2016 2016 live action adaptation]] of ''WesternAnimation/TheJungleBook1967'' and Warner Bros' [[Film/{{Mowgli}} 2018 live action adaptation]] of same, the giant snake Kaa is now a female. The major difference being that she's a [[AdaptationalVillainy villain]] in the 2016 work, a [[TruerToTheText hero]] in the 2018 one.
* The film adaptation of ''Film/JurassicPark'' switched the roles of Hammond's grandchildren, making Lex (the girl) the older one and the computer genius. This was done in order to give Lex more characterization. In the original novel Tim was a TeenGenius that was both computer savvy and obsessed with dinosaurs, while Lex was just annoying.
* Gazelle was a man in ''ComicBook/TheSecretService'', but a woman in ''Film/KingsmanTheSecretService''.
* In the [[Film/KPax film adaptation of]] ''Literature/KPax'', the novels' Dr. Klaus Villars -- a white, bearded, German-accented, classically Freud-reminiscent psychiatrist -- becomes Dr. Claudia Villars, a female Black-American played by Alfre Woodard.
* ''Film/JungleCruise'' features a female version of the ride's shrunken head salesman Trader Sam as the native tribe's chieftain, briefly donning a tophat much like the Walt Disney World version of the character.
* ''Film/KissOfTheSpiderWoman'': Molina was a transgender woman in the book, but is a cisgender man now.
* ''Film/LadyAndTheTramp2019'' changes Jock from male to female (her name becomes a nickname for Jacqueline), makes Jim Dear and Darling's baby a girl named Lulu instead of a boy, and changes the female Siamese cats into male [[AdaptationalSpeciesChange Devon Rexes.]]
* ''Film/{{Lantana}}'', based on ''Theatre/SpeakingInTongues'', turns Valerie's patient Sarah Phelan into a gay male patient, Patrick Phelan.
* In ''Film/LeftBehindRiseOfTheAntichrist'', which is loosely based on the second half of the first ''Literature/LeftBehind'' book, investigative reporter Eric Miller becomes Erica Miller working for GWN.
* ''Film/LegendOfEightSamurai'' has one of the eight half-brothers changed from a crossdressing male to a female portrayed by Creator/SueShiomi.
* In "Literature/LetTheRightOneIn" the vampire Eli despite being assumed to be female was actually a boy who was castrated as a child. In the American adaption "Film/LetMeIn" the vampire Abby is definitely female, there's even a deleted scene which shows Abby a female when she was turned.
* Creator/KennethBranagh's 2000 film adaptation of ''Theatre/LovesLaboursLost'' changed Holofernes into Holofernia, played by Geraldine [=McEwan=].
* The Creator/PatrickDempsey film ''Made of Honor'' is clearly this of the ''Creator/JuliaRoberts'' vehicle ''Film/MyBestFriendsWedding'', given their identical plots--person realizes that they're in love with their opposite-sex best friend just as said friend announces their engagement, is roped into being part of the bridal party and spends the ensuing time pulling numerous manipulative stunts to break up the relationship. In true DoubleStandard style, Julia Roberts character, a woman, is blasted for her behavior and does NOT get the guy, whereas Patrick Dempsey ends up married to the girl.
* In ''Film/{{Maleficent}}'' [[spoiler: Since [[CleverCrows Diaval]] becomes the iconic dragon, and not Maleficent, this would mean the dragon of this continuity is male.]]
* The original Music/{{ABBA}} recording of "Does Your Mother Know?" was an older man singing to a barely (or possibly not quite) legal girl, whereas in ''Theatre/MammaMia'' it's flipped to a middle-aged woman singing to the very persistent and very young man who's pursuing her.
* In place of Jimmy Olsen at the Daily Planet is a young woman named Jenny in ''Film/ManOfSteel''. [[FlipFlopOfGod However]] Jenny's last name is confirmed NOT to be Olsen, so there is room for a red headed male photographer in the sequel. If you pay attention, the movie shows her last name to be "Jurwich"... but one tie-in book makes it Olsen, so it's hard to say for sure.
* Franchise/MarvelCinematicUniverse:
** In ''Film/AvengersAgeOfUltron'', ComicBook/{{Hawkeye}}'s [[spoiler: youngest child (adapted from the second volume of ''ComicBook/TheUltimates'') is changed from a girl named Nicole to a boy named Nathaniel (after his "[[HonoraryAunt Auntie]] [[ComicBook/BlackWidow Nat]]".]] Lampshaded in-universe, as they mention that they were expecting a girl. [[spoiler:His middle child is also changed from a boy named Lewis to a girl named Lila. The oldest child is not flipped, although he does get a name change from Callum to Cooper.]]
** In ''Film/GuardiansOfTheGalaxyVol2'', Mainframe is a female android voiced by Creator/MileyCyrus, despite being a male, futuristic counterpart of ComicBook/TheVision.
** In ''Film/AntManAndTheWasp'', Ghost goes from being a white man to a [[RaceLift biracial]] woman.
** ''Film/{{Captain Marvel|2019}}'':
*** [[ComicBook/{{Captain Marvel|MarvelComics}} Captain Mar-Vell]] is a woman, played by Creator/AnnetteBening. The character's human alter ego is consequently changed from "Walter Lawson" to "Wendy Lawson."
*** Complicated example with the Kree Supreme Intelligence. [[spoiler: In the comics, the Supreme Intelligence is basically a giant floating head, but has nonetheless often been referred to with male pronouns (or none at all), and has always been voiced by male actors whenever it showed up in TV shows and video games. In the film, however, the Supreme Intelligence takes on a form unique to whoever it is talking to, meaning that when it appears onscreen to commune with Carol Danvers, it looks like the aforementioned Mar-Vell and is once again played by Bening.]]
** In ''Film/{{Eternals}}'', the characters Makkari, Ajak and Sprite, all of whom are men in [[ComicBook/TheEternals the original comics]], are played by women. The three of them were brought BackFromTheDead in the comics as woman [[RetCanon to match their portrayals here]].
** In ''Film/BlackWidow2021'', [[spoiler: Comicbook/{{Taskmaster}}]] turns out to be a woman, with the character's real name changed from [[spoiler:Anthony Masters to Antonia Dreykov]].
** Cosmo the Spacedog is male in the comics, but her first speaking role in ''Film/TheGuardiansOfTheGalaxyHolidaySpecial'' has her female. According to Creator/JamesGunn, this was to make her more like the character's real-life inspiration [[UsefulNotes/TheSpaceRace Laika]].
* Creator/VanessaRedgrave's role in ''Film/MissionImpossible'' was originally written for a man.
* Jacob Portman's male psychiatrist Dr. Golan from ''Literature/MissPeregrinesHomeForPeculiarChildren'' is played by actress Creator/AllisonJanney in [[Film/MissPeregrinesHomeForPeculiarChildren the film adaptation]], subverted in that like in the book [[spoiler:Dr. Golan turns out to be the false identity of a male Wight]].
* In the Creator/JossWhedon film of Shakespeare's ''Theatre/MuchAdoAboutNothing'', one of the villain's lackeys, named Conrad, is female. The part has always been, in the past, a basic male role.
* In ''Film/MuppetTreasureIsland'', Ben Gunn from ''Literature/TreasureIsland'' is changed to Benjamina Gunn just so [[Franchise/TheMuppets Miss Piggy]] can have a role to play.
* The remake of ''Film/{{Overboard|2018}}'' gender flips the two main characters from the original movie.
* The character Carin from ''Film/PatchAdams'' is a female medical student who Patch has a romantic relationship with, was molested as a child and is eventually killed by a mentally ill patient. In reality, "she" was Hunter Adams' best male friend, who he did not have a romantic relationship with, and while he was killed under similar circumstances, it was much earlier than the film depicts. This was one of the many reasons the RealLife Hunter Adams has openly criticised the movie based on his life.
* ''Film/{{Ran}}'' is a partial Gender Flip of ''Theatre/KingLear'', changing the gender of the daughters and Edmund.
* ''Film/{{Rags}}'' is a gender flip of ''Literature/{{Cinderella}}'', where Cinderella is now a boy named Charlie with a stepfather and stepbrothers, and the Prince is a female popstar named Kadee Worth.
* The [[Film/TheRelic film adaptation]] of ''Literature/TheRelic'' saw Linda Hunt play the museum director Anne Cuthbert, a character who, in the original novel, was a man named Ian Cuthbert.
* In ''Film/TheReturnOfSherlockHolmes'', Doctor Watson is a woman, played by actress Bessie Nellis.
* Nearly every adaptation of ''Literature/TheRing'' changes the male protagonist into a female, and his baby daughter into a kid son. The only adaptation to keep the protagonist male is an obscure 1995 Japanese MadeForTVMovie called ''Ring: Kanzenban''.
* ''Film/RoboCop2014'' sees Anne Lewis changed into an [[RaceLift African-American]] man named [[AdaptationNameChange Jack]] Lewis. Conversely, Chief Dean is a female version of Sgt. Reed.
* Most shadowcasts of ''Film/TheRockyHorrorPictureShow'' will let anyone, regardless of gender, audition for any part. ("Genderfuck" versions specifically gender flip ''all'' the roles.)
* ''Film/RoughNight'' is the same premise as ''Film/VeryBadThings'' with the genders reversed.
* The 2022 remake of ''Literature/SalemsLot'' has Dr. Cody, a man in the original novel and prior adaptations, played by Creator/AlfreWoodard.
* The title character of ''Film/{{Salt}}'' was originally named Edward and played by Creator/TomCruise, but he dropped out. When Creator/AngelinaJolie stepped in, the writers changed Ed to Evelyn and also decided to make Salt's spouse less of a DamselInDistress.
* The film version of ''[[Series/ThePhilSilversShow Sgt. Bilko]]'' turned Cpl Rocky Barbella into Cpl Raquelle Barbella. (Bilko's other sidekick, Cpl Henshaw, was given a RaceLift).
* The movie adaptation of ''Film/SilentHill'' replaced Harry Mason with Rose Dasilva. The idea was to play up the notion that a mother is even more attached to her child than a father, particularly if the child is a girl. Interestingly, the father was played by Creator/SeanBean, who does look a bit like Harry Mason. In the sequel, Bean's character has taken the name Harry Mason, but still isn't the protagonist.
* In ''Film/SodomAndGomorrah'', King Bera of Sodom from the Literature/BookOfGenesis becomes Queen Bera of Sodom.
* Spotted in ''Film/SonOfMan'', an adaptation of the story of Jesus Christ that takes place in modern Africa. Several of the disciples are portrayed by women, with feminized versions of their original names to match.
* The character of Dizzy Flores in ''Franchise/StarshipTroopers'' was a man in the [[Literature/StarshipTroopers original Robert A. Heinlein novel]]. In the [[Film/StarshipTroopers movie]], he was switched to a she, given a much bigger role, and played by Dina Meyers. ''WesternAnimation/RoughnecksStarshipTroopersChronicles'' followed the movie's lead. [[note]]It may be more accurate to say that Dizzy Flores was turned into a character, as well as a woman, in the movie. In the book, Dizzy has no lines, only appears near the end of chapter 1, and dies at the end of it.[[/note]]
* The 1996 made-for-TV movie, ''The Stepford Husbands'' is, as its name suggests, ''Literature/TheStepfordWives'' with the gender roles reversed-this time it's the women seeking to make their husbands "perfect".
* The original screenplay for ''Film/StreetsOfFire'' had the role of [=McCoy=], the hero's old army buddy, written as a male. Actress Amy Madigan, while auditioning for a different role, convinced the filmmakers to let her play [=McCoy=] as a tough, strong woman instead, without rewriting the part.
* ''Film/TheSuicideSquad'' makes the Ratcatcher, a middle-aged male in the comics, into a teenage girl. Downplayed in that the character is named Ratcatcher 2, implying she's the original male Ratcatcher's CanonForeigner [[AffirmativeActionLegacy successor]].
* In ''The Survivor'', Hobbs (played by Creator/JennyAgutter) was a man in Creator/JamesHerbert's original novel.
* The female lead of the 1982 ''Film/SwampThing'' movie is a government agent named Alice Cable, based on Agent ''Matthew'' Cable from the original comics.
* In ''Film/TeenageMutantNinjaTurtles2014'', April's boss Burne Thompson is now an [[RaceLift African-American]] woman named Bernadette Thompson, played by Creator/WhoopiGoldberg.
* In ''Film/TheTempest2010'' directed by Julie Taymor, the character Prospero is changed to Prospera and played by Creator/HelenMirren.
* ''Film/TwilightZoneTheMovie'': In "Kick the Can", the Sunnyvale Retirement Home administrator is Miss Cox. In the [[Recap/TheTwilightZoneS3E86KickTheCan original episode]], it is Mr. Cox.
* And it happened again during the production of ''Film/VantagePoint'' (2008), where Sigourney Weaver played the also originally male TV producer Rex Brooks.
* In ''Film/WarCraft2016'', [[spoiler:Alodi]], who's male in the game the film's based on, is female (or at least [[AFormYouAreComfortableWith female-appearing]]).
* ''Film/WeeWillieWinkie'' was based on a Creator/RudyardKipling short story in which the protagonist was a little boy. When the story was adapted for the screen, it became a Creator/ShirleyTemple vehicle, and the main character became a girl.
* In the original novel version of ''Film/WintersBone'', protagonist Ree had two younger brothers. In the film version, one of them is a girl.
* In BMovie series ''Witchcraft'' (possibly best known from Creator/AllisonPregler's reviews) a police officer named Lutz first appears as a man in the sixth film and is suddenly a woman in the seventh, with no explanation. The thirteenth and final film, in its valiant attempts to close all the series' {{Plot Hole}}s, {{Ret Con}}ned the two Lutzes into siblings.
[[/folder]]

[[folder:Live-Action TV]]
* ''Series/TwelveMonkeys'', an adaptation of the [[Film/TwelveMonkeys 1995 movie]], has Jeffrey Goines turn into ''Jennifer'' Goines.
* In ''Series/TheAdventuresOfShirleyHolmes'', Sherlock's descendant and {{Expy}} is his great-grandniece. And her archenemy is [[PunnyName Molly Hardy]].
* In ''Series/{{Arrow}}'', the African-American PosthumousCharacter Paula Holt becomes a white guy called Paul. [[AdaptationalSexuality Still married to Mr Terrific, though.]]
* In the second series of ''Series/TheAvengers1960s'', Creator/HonorBlackman (as Dr. Cathy Gale) replaced Creator/IanHendry (Dr. David Keel) as John Steed's partner. In her earliest appearances (scripts written much earlier for Hendry), her dialogue was left completely unchanged. This is sometimes credited with making Cathy Gale a particularly memorable female character for the early '60s.
* ''Series/BattlestarGalactica2003'':
** Starbuck and Boomer are Gender Flipped (and {{Race Lift}}ed) from [[Series/BattlestarGalactica1978 the original]]. As often happens with actors who find themselves replaced, Creator/DirkBenedict was less than happy about it, referring to his heir as "Stardoe" (har har). Creator/KevinSmith joked about this when he hosted a ''Battlestar Galactica'' panel at Comic Con.
--->'''Smith:''' ''[to Ron Moore and David Eick]'' I'm glad you guys changed Starbuck into a woman. Otherwise it would have made all those kissing scenes with Lee really awkward.
** Lloyd Bridges' Commander Cain was also revived as Michelle Forbes' (now Admiral) Helena Cain. But they're both equally crazy.
* Jonathan Cartwright/Mouse in ''Series/Batwoman2019'' is a GenderFlip of Batman villain Jane Doe, who likewise impersonates people with flayed-skin masks, and was named as Jane Cartwright in ''Series/{{Gotham}}''.
* The production of ''Theatre/SwanLake'' put on in ''Series/TheBigLeap'' uses genderblind casting. This coupled with several cast changes causes several roles to have this. Simon is Odile the Black Swan, Brittney is briefly Prince Siegfried, Aja is Von Rothbart by the final production, and the show makes a big deal out of casting two women as the Siegfried's parents (with a sound cue that bellows "'''two mommies'''" whenever it's brought up).
* ''Series/TheBionicWoman'' is a gender flipped reimagining of ''Series/TheSixMillionDollarMan'', at least one episode of which was plot and dialogue identical. At the end, the titular hero has to provide an impromptu explanation of how his or her finger came to be cut. The explanation given in both cases was "I [[CutHimselfShaving cut myself shaving]]".
* In ''Series/BlackLightning2018'', Erica Moran is a gender-flipped version of Freight Train from ''ComicBook/BatmanAndTheOutsiders'', real name Eric Moran.
* Servalan in ''Series/BlakesSeven'' was originally a man and was originally supposed to appear once. Once Jacqueline Pearce entered the picture, that all changed.
* ''Series/TheBoys2019'': Madelyn [[note]]James[[/note]] Stillwell and Grace [[note]]Greg[[/note]] Mallory. Season 2 has Stormfront played by a woman while "Vic the Veep" Neumann is reimagined into Victoria Neumann.
* ''Series/BraveNewWorld'': Mustapha Mond, the male World Controller in the book, is now female.
* In the Japanese mini-series ''[[Manga/BloodOnTheTracks Chi no Wadachi]]'', the investigator character is played by Creator/TaoOkamoto. The character was a man in the original novel.
* In the ''Series/DeathNote'' live-action drama, Near, who is a boy in the manga, was played by a teenage girl and deliberately had their gender [[AmbiguousGender left ambiguous]].
* ''Series/DoctorWho'':
** In "[[Recap/DoctorWhoS2E5TheWebPlanet The Web Planet]]", the character Vrestin, leader of the Menoptera war party, was written as male (like all the other Menoptera). However, when casting the character, the cast and crew were impressed with the choreographer hired to create the 'insect movement' and cast her as Vrestin without changing anything in the script besides pronouns, resulting in one of the most powerful ActionGirl supporting characters in 60s ''Who''. Vrestin is male in the Target novelisation of the story (''Doctor Who and the Zarbi''), which is based on the original script.
** In "[[Recap/DoctorWhoS3E1Galaxy4 Galaxy 4]]", the Drahvins were originally all male, until producer Verity Lambert suggested making them all-female.
** Gia Kelly in "[[Recap/DoctorWhoS6E5TheSeedsOfDeath The Seeds of Death]]" was originally a man.
** Morgan in "[[Recap/DoctorWhoS8E4ColonyInSpace Colony in Space]]" was originally a woman, with Susan James cast in the role. However, she was replaced by Tony Caunter when the BBC's Head of Drama Serials made an unusual intervention and decided the role was inappropriate for a woman to perform. James was nevertheless paid in full.
** The human president in "[[Recap/DoctorWhoS10E3FrontierInSpace Frontier in Space]]" was originally a man.
** Bettan in "[[Recap/DoctorWhoS12E4GenesisOfTheDaleks Genesis of the Daleks]]" was originally a man. Aside from Sarah Jane Smith, she's the only female character in the story.
** Marn in "[[Recap/DoctorWhoS15E4TheSunMakers The Sun Makers]]" was originally a man.
** Dr. Solow and Preston in "[[Recap/DoctorWhoS21E1WarriorsOfTheDeep Warriors of the Deep]]" were originally men, until director Pennant Roberts made them female. Roberts usually gender-flipped at least one role in every story he directed.
** Averted in "[[Recap/DoctorWhoS21E7TheTwinDilemma The Twin Dilemma]]", as Creator/JohnNathanTurner was encouraged to cast two more experienced female actresses in the roles of the CreepyTwins, but chose male actors because he believed it was crucial the characters be boys for the script to work. He [[RuleOfSymbolism may have had a point about this]] (the twins can be read as a PlotParallel for the Doctor's fragmented personality following his regeneration).
** The stage play adaptation of "[[Recap/DoctorWhoS14E5TheRobotsOfDeath The Robots of Death]]" turns Uvanov, Borg, Cass and Dask into women. One would think that this was being done to obscure which character is secretly the pro-robotist terrorist Taren Capel, but the main characters refer to Taren as 'she' from the beginning. Another side effect of this is that it means the only surviving male character of the story is Poul (who exists as a gibbering vegetable).
** Pope Benedict IX is portrayed as a woman in "[[Recap/DoctorWhoS36E6Extremis Extremis]]". Considering the scandalous nature of his reign, this was probably much safer than portraying him accurately. It also doubles as a ShoutOut to the legend of Pope Joan. However, [[spoiler:it's later revealed that nearly the entirety of the episode was part of a simulation.]]
* ''Series/DoomPatrol2019''
** Cyborg's childhood friend Ron Evers is now his love interest ''Roni'' Evers.
** The Brotherhood of Dada is now the Sisterhood of Dada, although in fact, only two members are examples: the Fog (whose real name is changed from Byron Shelley to Shelley Byron) and the Quiz (whose real name was never revealed in the comics). Sleepwalk was already a woman and Frenzy remains male, as is [[CanonForeigner new member]] Malcolm.
* In ''Literature/{{Dracula}}'', Van Helsing is a man. In ''Series/Dracula2020'', there are [[DecompositeCharacter two]] Van Helsings, both female.
* In another Franchise/SherlockHolmes adaptation, ''Series/{{Elementary}}'', John Watson has been changed to Joan Watson and is played by Creator/LucyLiu. As Liu is Chinese American, this is a RaceLift [[TwoferTokenMinority as well]]. Also, [[spoiler: Moriarty]] is now a [[spoiler: woman]] and is combined with [[spoiler:Irene]].
* One of the episodes of the new ''Series/FantasyIsland'' featured a terminally ill woman who wanted to experience life as a soldier in a combat zone. Instead of being placed with a company of male soldiers like she expected, she was placed in a gender-reversed version of TheSquad, which was filled with the requisite roughneck personality types, only with women playing the roles.
* ''Series/TheFlash2014'':
** A crossover event between that show and ''Series/{{Arrow}}'' introduced a Gender Flip of ComicBook/TheAtom's enemy, the Bug-Eyed Bandit, with "Bertram Larvan" becoming "Brie Larvan" (portrayed by Creator/EmilyKinney).
** Season 3 introduces the Top as a young woman, with the character's name changed from "Roscoe Dillon" to "Rosalind 'Rosa' Dillon" (portrayed by Ashley Rickards).
** Season 4's "Luck Be A Lady", introduces Becky "Hazard" Sharp, who is female in both the series and the comics ... except the details of how her WindsOfDestinyChange powers work are altered slightly to essentially make her a gender flip of Amos Fortune, specifically the way he's presented in ''[[ComicBook/JusticeLeagueInternational Justice League Europe]]''.
** Season 4 also introduces the show's version of Black Bison, who is a woman named Mina Chayton instead of a man named John Ravenhair.
** Also in Season 4 is a version of Fiddler, who instead of an elderly man named Isaac Bowen is a younger woman named Izzy Bowen.
** And obscure ''ComicBook/{{Hawkman}}'' character Null, who's a woman named Janet Petty instead of a man named, well, Null, as far as we know.
** Joss Jackam, the Weather Witch, is very loosely based on Weather Wizard's son in the comics, Josh Jackam.
** Season 5 introduces Spin, who is changed from a man known only as Mr. Auerbach to a woman named Spencer Young.
** Evan [=McCulloch=], a.k.a Mirror Master II, is adapted as Eva [=McCulloch=].
** The Red Death is an alternate universe version of [[Comicbook/{{Batman}} Bruce Wayne]] in the comics, but in the series, Red Death is instead [[spoiler:an alternate incarnation of Ryan Wilder, the second Series/{{Batwoman|2019}}]].
* In the TV movie that inspired ''Series/ForeverKnight'', the medical examiner and SecretKeeper who'd met Nick when he woke up in the morgue had been male.
* ''Series/FullerHouse'' flips the genders of its antecedent series. In the original, Danny Tanner (a man) raised three girls with help from his two pals (also men), in the new show, DJ Tanner (a woman) raises three boys with help from her two pals (women).
* ''Series/GameOfThrones'':
** For an unknown reason, the Dornish practise of open succession (i.e a firstborn girl inherits before her younger brother) was erased. This leads to some notable Dornish ladies who rule in their own right being changed into men. In particular, Oberyn refers to his father as being Prince of Dorne before him, when in actual fact his mother was the reigning Princess. And in the books, the head of the delegation Tyrion meets outside King's Landing is a woman. An HBO press release named Prince Trystane rather than [[AdaptedOut Princess Arianne]] as the heir to Prince Doran Martell.
** Bronn's betrothed Lollys is said to be a daughter of ''Lord'' Stokeworth rather than the elderly Lady Tanda Stokeworth of the novels.
** House Cerwyn was actually headed by a ''woman'' at the point in the novels where they are introduced in the show, Jonelle Cerwyn, after the Boltons killed her father and brother. The TV version omitted Jonelle and kept her brother alive — actually part of a pattern of gender-swapping minor background vassals from female to male.
* ''Series/TheGoldbergs'' depicts producer Adam Goldberg's life in TheEighties, but with one major difference: in real life, he has two brothers, Barry and Eric. On the show, he has a brother Barry and a sister Erica.
** This particular example gets an InUniverse inversion in "8-Bit Goldbergs". In Adam's computer game based on his family, Erica is replaced by a man named Eric and her boyfriend Geoff Schwartz becomes Eric's girlfriend Geoffina.
* ''Series/GoodOmens2019'': Pollution is nonbinary, referred to in the narration as "they", and played by a woman. Beelzebub is a woman as well, as are the Archangels Michael and Uriel, and most notably God Herself (but she's just a voice).
* ''Series/{{Gotham}}'' changes Firefly from a white male named Garfield Lynns to a young Latina woman named Bridget Pike (played by Michelle Veintimilla).
* A zig-zagged example takes place in Series/HallmarkHallOfFame's 2005 miniseries ''Hercules''. In this adaptation, the Nemean Lion is a male animal, but it can turn into a beautiful woman in order to seduce their enemies into letting their guard down. Then again, the miniseries fuses this character with the Theban Sphynx, so the monster is probably female after all, only that its true form looks like a male lion.
* ''Literature/RedDragon'''s male reporter Freddie Lounds becomes the female reporter Fredricka Lounds in the TV adaptation ''Series/{{Hannibal}}''. In the same show, forensic psychiatrist Dr. Alan Bloom becomes Alana Bloom and is given some angsty {{UST}} with Will Graham.
* ''Series/TheHardyBoys2020'': Biff Hooper, a teenage boy in [[Literature/TheHardyBoys the novels]], is made into a teenage girl in the Creator/{{Hulu}} series.
* ''Series/HawaiiFive0'' makes Kono a woman (renamed Kona, but still nicknamed "Kono"). She's played by Grace Park, who was previously best known as the gender-flipped Boomer in ''Series/BattlestarGalactica2003''.
* ''It Happened One Christmas'' (1977) is a TV-Movie Gender Flip of ''Film/ItsAWonderfulLife'' starring Marlo Thomas. Played completely straight.
* ''Literature/HighFidelity'': Rob, originally a man in the book, film and musical is made a woman for the series.
* ''Series/InterviewWithTheVampire2022'': Antoinette Brown (a woman) is based on Antoine (a man) from ''Literature/TheVampireChronicles'', a musician (although she's more precisely a singer) who becomes Lestat de Lioncourt's lover and is later turned into a vampire.
* ''Series/ItsAlwaysSunnyInPhiladelphia'' spoofs the trope in "The Gang Beats Boggs: Ladies' Reboot", where Dee leads a delegation of the show's female characters in rehashing the concept of a previous EpisodeOnAPlane. Artemis keeps complaining that the idea is lazy and suggesting that they do something new instead.
* ''The Jungle Book: Mowgli's Story'' gender-bends Bagheera - and Bagheera alone - so that s/he's a female for the duration of a movie. This is probably so that Mowgli can have a mother-figure without adding in Mother Wolf, the she-wolf from the book, but it can be a little odd for a kid only familiar with the Disney version.
** It's not the first time that Bagheera was a female. The Soviet series ''Animation/AdventuresOfMowgli'' did the same. Due to how Bagheera has a feminine pronunciation in Russian.
* Mrs. Lee from ''Series/KimsConvenience'' was a man named ''Mr.'' Lee in the original play.
* In ''Series/{{Krypton}}'', the terrorist Jax-Ur is an attractive woman in her 40s instead of an old man.
* ''Series/LegendOfTheSeeker'': In the books, everyone refers to the Creator as "he". Here, it's the opposite, and her ([[MaybeMagicMaybeMundane apparent]]) human avatar is a woman.
* ''Series/LetTheRightOneIn'': Eli in the novel is a castrated boy. Eleanor is a girl.
* ''Series/LockwoodAndCo2023'': Pamela Joplin was Albert Joplin in [[Literature/LockwoodAndCo the book series]], while Fairfax's assistant Ellie was a big hulking male thug named Grebe.
* In ''Series/LostInSpace2018'', Dr. Zachary Smith is now a woman played by Creator/ParkerPosey. [[spoiler:In a subversion, it actually turns out that "Dr. Smith" is a con woman who stole the identity of this continuity's Zachary Smith.]]
* ''Series/LovecraftCountry'' has a few examples, such as George and Hippolyta's son Horace becoming their daughter Dee, and Caleb Braithwaite becoming Christina Braithwaite.
* ''Series/Lucifer2016'':
** The angel Remiel is a white man in [[ComicBook/{{Lucifer}} the comics]], but is depicted as an Asian woman in the show.
** Gabriel is also changed from a white male to an AmbiguouslyBrown woman.
* In ''Series/MacGyver1985'', the title character took his orders from Pete Thornton. In the [[Series/MacGyver2016 reboot]], this role is filled by ''Patricia'' Thornton [[spoiler: until she's discovered to be a mole for the enemy, arrested, and replaced by Matty Webber.]]
* ''Franchise/MarvelCinematicUniverse'':
** In ''Series/TheFalconAndTheWinterSoldier'', the Flag-Smasher is a woman named Karli Morgenthau rather than a man named Karl Morgenthau.
** In ''Series/Hawkeye2021'', Detective Rivera is a man, rather than a woman.
** Jeryn Hogarth, a male lawyer in the comics, is played by Creator/CarrieAnneMoss in ''Series/JessicaJones2015'', with the character becoming "Jeri Hogarth" instead. [[AdaptationalSexuality Still attracted to women, though.]]
** Zigzagged with ''Series/MoonKnight2022''. While Layla El-Faouly is loosely based on Marc Spector's wife, Marlene, she also becomes a female version of [[spoiler: The Scarlet Scarab]]. Her last name "Faouly" is a reference to the Abdul & Mehemet Faoul, who used the alias in the comics.
* The Japanese series ''Series/MissSherlock'' is an update of Sherlock Holmes set in modern day Tokyo. Sherlock becomes Sara "Sherlock" Futaba, while Watson becomes Wato Tachibana.
* ''Series/Missing2012'' (female secret agent searches for her kidnapped son) seems to be a gender-flipped TV version of ''Film/{{Taken}}'' (male ex-secret agent searches for his kidnapped daughter).
* In-universe example: In the ''Series/{{Monk}}'' episode "Mr. Monk and the Actor", there's a movie adaptation being made of the Steve Wagner case (in "Mr. Monk and the Astronaut"). In this movie, Monk is played by method actor David Ruskin (Creator/StanleyTucci), Natalie is played by a blonde actress, and Captain Stottlemeyer is a cameo appearance by Creator/PeterWeller. As for Randy Disher, he was wholly expecting Creator/BradPitt to be portraying him in the movie. Instead, Randy is replaced with a gorgeous brunette actress who becomes a love interest for Captain Stottlemeyer. The real Stottlemeyer and Disher don't know this when they show up on the set to watch a rehearsal, leading to a ''very'' awkward moment when the actors lean in for a kiss.
-->'''Captain Leland Stottlemeyer:''' That ''never happened''.\\
'''Lt. Randall Disher:''' Not even once.
* ''Series/{{Monkey}}'', an adaptation of ''Literature/JourneyToTheWest'', changed the gender of certain characters: Tripitaka is now a woman, Buddha is a goddess and Guanyin a god.
* Creator/TheBBC's 2012 SettingUpdate of ''Literature/NicholasNickleby'' has Nick working at a BleakAbyssRetirementHome called Dotheolds Hall, in place of the BoardingSchoolOfHorrors Dotheboys Hall. Smike, the "simple" boy Nicholas befriends and rescues from the place, becomes a senile old lady named Mrs. Smike.
* In ''Literature/TheNightmareRoom'' episode "My Name Is Evil", the protagonist is male when she was female in the original story. The protagonist's peers were similarly gender flipped.
* ''Series/OnceUponATime'' changes Jack the Giant Killer to ''Jacqueline'' the Giant Killer.
* In ''Series/OnePiece2023'', Sham, one of Kuro's minions, in a woman, while her [[Manga/OnePiece manga]] counterpart is a man.
* ''Series/TheOuterLimits1963'': In "[[Recap/TheOuterLimits1963S2E9IRobot I, Robot]]", Dr. Charles Link's closest living relative is his niece Nina. In the 1939 short story "[[Literature/AdamLink The Trial of Adam Link, Robot]]" by Eando Binder on which it is based, his closest relative is his nephew Tom.
* ''Series/PartOfMe'': In both ''El cuerpo del deseo'' and ''En cuerpo ajeno'', it was an older man who [[SharingABody inhabited the body of a younger man]]; here, it's an older woman inhabiting the body of a younger woman.
* ''Franchise/PowerRangers'': The fullest effects of this trope are best seen in the seasons that are actual adaptations of the source shows including character portrayals, though for some instances, this trope applies only in combat when the Ranger adaptation would only use fight footage rather than adapting episode plots.
** When ''Series/KyoryuSentaiZyuranger'' was "[[ForeignRemake remade]]" into ''Series/MightyMorphinPowerRangers'', the male Tiger Ranger became the female Yellow Ranger in order to have [[TwoGirlsToATeam two female Rangers]] instead of [[SmurfettePrinciple just one]]. This practice started a trend for Yellow Rangers when four later ''Franchise/SuperSentai'' shows were adapted into ''Franchise/PowerRangers'' seasons: the male Yellow Rangers from ''[[Series/SeijuuSentaiGingaman Gingaman]]'', ''[[Series/RescueSentaiGoGoFive Gogo-V]]'', ''[[Series/MiraiSentaiTimeranger Timeranger]]'' and ''[[Series/HyakujuuSentaiGaoranger Gaoranger]]'' were turned into females in their corresponding adaptations (''[[Series/PowerRangersLostGalaxy Lost Galaxy]]'', ''[[Series/PowerRangersLightspeedRescue Lightspeed Rescue]]'', ''[[Series/PowerRangersTimeForce Time Force]]'', and ''[[Series/PowerRangersWildForce Wild Force]]''). This practice would cause inconsistencies between the imported Japanese footage and the locally-filmed new footage, in which the Yellow Ranger would switch from having a masculine figure in one scene to having a feminine one in the next.
** Tsuruhime, the ''Series/NinjaSentaiKakuranger'' White Ranger, underwent heavy DecompositeCharacter treatment. Of the three characters to take on her roles, two (Alien Ranger Delphine and MMPR Katherine) were still women, while her role as team leader and one of her Zords went to the male Tommy Oliver.
** Katie from ''Series/PowerRangersTimeForce'' was made similar to Domon from ''Timeranger'', although many of the latter's traits were given to Lucas and Trip. From what was left, Domon's nostalgia for sumo wrestling competitions got adapted as Katie missing her family, a much more emotional and feminine intake on the feeling; similarly, the subplot with Domon's relationship with a female photographer who discovered his identity was changed to a one-off deal between Katie and a male photographer who unmasked her that didn't go anywhere, due to males pursuing relationships being less common (and to make room for focus on the [[SpotlightStealingSquad Rangers who wore any]] [[LawOfChromaticSuperiority shade of red]]).
** Taylor from ''Series/PowerRangersWildForce'', on the other hand, was almost identical to Gaku from ''Gaoranger'' in terms of background and plot, the only major differences being personality (Taylor was a bold DefrostingIceQueen, Gaku was friendly from the very beginning and somewhat quirky) and rank (Taylor was a lieutenant, whereas Gaku was a soldier). As a female {{Lancer}} was proven successful the previous season, Taylor got a better end of the stick than her yellow predecessor, who was TheBigGuy and therefore more expendable.
* ''Series/QueenOfSwords'' was pretty much a straight Gender Flip of {{Franchise/Zorro}}, to the point that Sony sued over its resemblance to the character and its 1998 ''Film/TheMaskOfZorro'' film.[[note]]The judge ruled against Sony, holding that both the original Zorro story and its first (1920) film adaptation were now in the public domain, and any similarities to the 1998 film were incidental.[[/note]]
* The crew of the ''Series/RedDwarf'' ''meet'' the Gender Flipped versions of themselves in a parallel universe. Although, not all of them were flipped. The Cat, the ultimate narcissist, is looking forward to meeting the feminine version of himself for... obvious reasons. However, his opposite number is a male Dog with zero dress sense.
** Eventually, when Creator/NormanLovett, who played Holly, left, they just hired Creator/HattieHayridge, who played his Gender Flip Hilly and said that Holly got a sex change to look like Hilly.
** Captain Hollister is a man in the TV series, and a woman in the tie-in novels.
** In the second pilot for the US version, the Cat was played by Terry Farrell (who would go on to be Jadzia in ''Series/StarTrekDeepSpaceNine'') as a "feline warrior woman". (The original pilot had Hinton Battle playing the role much as Danny John-Jules did.) In the end, the American remake never aired anyway.
* ''Series/Revenge2011'', a modern-day reimagining of ''Literature/TheCountOfMonteCristo'', gender-flips the protagonist Edmond Dantes to be Emily Thorne. Rather than having been framed herself like Edmond, Emily is the daughter of a man who was framed and falsely imprisoned.
* In the anthology series ''Series/TheRivalsOfSherlockHolmes'', one episode adapts Robert Barr's "The Absent-Minded Coterie". The clever Mr. Macpherson becomes the equally clever Miss Mackail.
* Djaq in ''Series/RobinHood'' is a Gender Flip of the Saracen outlaw seen in ''Series/RobinOfSherwood'' (Nassir) and ''Film/RobinHoodPrinceOfThieves'' (Azeem). ... And ''Film/RobinHoodMenInTights'' (Achoo).
* Lucky in ''Series/TheSchoolNurseFiles'' was a boy in the original novel, but the director changed him into a girl for the series.
* The American remake of the Australian show ''Secrets & Lies'' transforms lead investigator Ian Cornielle into Andrea Cornell.
* Due to being unable to find suitable actresses, the Indian remake of ''Series/ShakeItUp'' rewrote the leads as boys.
* ''Series/{{Sherlock}}'':
** Watson's brother, "H. Watson", mentioned in "The Sign of Four", becomes John's ''sister'', Harry (short for Harriet).
** "[[Recap/SherlockS02E02TheHoundsOfBaskerville The Hounds of Baskerville]]": Dr. James Mortimer becomes Dr. Louise Mortimer.
** Laura Lyons becomes a young, male Corporal Lyons.
** Stapleton is a trickier case; there's a Mr. Stapleton and Miss Stapleton in the book, but only one (female) Dr. Stapleton in the programme. The plot's been changed sufficiently that you can't tell which one she's meant to be by her actions.
** The King of Bohemia becomes an unnamed female British royal in "[[Recap/SherlockS02E01AScandalInBelgravia A Scandal in Belgravia]]".
** In John's CharacterBlog, Dr Barnicot from "The Adventure of the Six Napoleons" becomes [[http://www.johnwatsonblog.co.uk/blog/19december Sally Barnicot]].
** In the actual episode "[[Recap/SherlockS04E01TheSixThatchers The Six Thatchers]]", which probably makes the above blog post CanonDiscontinuity, there is a brief reference to one of the busts belonging to a Miss Orrie Harker, counterpart to the original's Horace Harker.
** In the same episode, DI Stella Hopkins is based on Inspector Stanley Hopkins, introduced in "The Adventure of the Abbey Grange".
* In the American version of ''Series/{{Skins}}'', most characters are transplanted from the British series except for the openly gay Maxxie. Maxxie becomes the lesbian Tea. The fact that they followed the same storyline with the character sleeping with Tony has several UnfortunateImplications.
* In ''Series/StarTrekTheOriginalSeries'', Creator/GeneRoddenberry sort of gender flipped the First Officer role, which was originally written as an emotionally distant, supremely rational NumberTwo (named "Number One"). NBC objected, however (not due to the casting of a female so much as the casting of the ''particular'' female, Majel Barrett, who happened to be Roddenberry's mistress at the time.) While different in several ways (most obviously, being an alien), Mr. Spock essentially assumed both her role as First Officer and her [[TheSpock rationality and lack of emotion]].
* ''Series/Supergirl2015'':
** Dr. Emil Hamilton is changed to Dr. Amelia Hamilton.
** N'or Cott was a male Martian in the comics, but is briefly mentioned in "Rebirth" with female pronouns.
* In ''Series/SupermanAndLois'', General Hardcastle from [[WesternAnimation/SupermanTheAnimatedSeries the 90s cartoon]] is a woman.
* The CBS All Access adaptation of ''Series/TheStand2020'' changed the Rat Man into the Rat Woman.
* When a {{Revival}} of ''Series/TheTimeTunnel'' was attempted in 2002, male scientist Dr. ''Tony'' Newman was changed to female scientist Dr. ''Toni'' Newman.
* ''Series/TheUmbrellaAcademy2019'': In [[ComicBook/TheUmbrellaAcademy the comics]], Vanya is a cis woman. In the show, ''Viktor'' comes out as a trans man in Season 3 due to Creator/ElliotPage's [[QueerCharacterQueerActor own gender transition]].
* In the books of ''Series/TheVampireDiaries'', Elena had a 4-year-old sister. In the TV show, she has a teenage brother. The boarding house Stefan stayed in was also owned by an elderly woman instead of Stefan's and Damon's "uncle".
* This isn't unique to ''Power Rangers'' either. Priest Poe from ''Series/SpaceSheriffShaider'' was a transvestite, but his ''Series/VRTroopers'' equivalent was a woman named Despera.
* ''Series/TheWalkingDead2010'' does this to a few notable characters from [[ComicBook/TheWalkingDead the comics]]:
** The male Dr. Stevens from the comics subverts this. His name is given to a woman, [[InNameOnly but it turns out]] that he's a DecompositeCharacter, and Dr. Stevens' CharacterDevelopment from the comics is given to Milton Mamet, who is also male.
** Twins Ben and Billy become sisters Lizzie ([[AgeLift older]]) and Mika (younger), respectively. [[DecompositeCharacter Ben does appear beforehand, though]].
** In Season 5, Alexandria Safe-Zone's first couple Douglas and Regina Monroe, respectively, are introduced as Deanna and Reg Monroe.
* ''Series/Warehouse13'' plays with this trope; H.G. Wells is split into two people; the real H.G. Wells is Helena G. Wells, the genius inventor, adventurer, and warehouse agent. The man recognized as Creator/HGWells is her older brother Charles, who chronicled her adventures using her abbreviated name as a pen name.
* The ''Series/WarriorNun'' Creator/{{Netflix}} series changes Julian Salvius to ''Jillian'' Salvius.
* ''Series/WillAndGrace''. Will wanted to stage an all-male rendition of ''Literature/BenHur'' titled "Ben-Him". Grace mentioned her mother appeared as "Millie Loman" in "Death of a Sales Lady". Grace's mother also mentions not even wanting to audition for 'The Ice-Person Cometh'.
* The title character in Creator/{{NBC}}'s live broadcast of ''Theatre/TheWiz'' is played by Music/QueenLatifah:
-->'''Dorothy:''' The Wiz is...\\
'''Cowardly Lion:''' ...a fraud!\\
'''Tinman:''' ...and a woman!\\
'''Dorothy:''' ''And what's wrong with being a woman?''
* ''Series/TheTwilightZone1959'':
** In "[[Recap/TheTwilightZone1959S1E16TheHitchHiker The Hitch-Hiker]]", the protagonist is a woman named Nan Adams. In ''The Orson Welles Show'' radio play by Lucille Fletcher on which it was based, the protagonist is a man named Ronald Adams. [[CreatorBacklash Fletcher was not pleased by this change]]. Furthermore, in the radio version, Ronald picks up a woman and briefly gives her a lift, but she leaves after he tries to run over the hitch-hiker. In the television version, Nan gives a lift to a male sailor, who leaves for the same reason.
** In "[[Recap/TheTwilightZone1959S3E24ToServeMan To Serve Man]]", a translator named Betty discovers [[ToServeMan the true meaning]] of the Kanamit book ''To Serve Man''. In the short story by Creator/DamonKnight, it is a man named Gregori.
** In "[[Recap/TheTwilightZone1959S3E29FourOClock Four O'Clock]]", Oliver Crangle's parrot is a male named Pete. In the short story by Price Day, the parrot is a female named [[ADogNamedDog Pet]].
** In "[[Recap/TheTwilightZone1959S4E5Mute Mute]]", the telepathic child is a girl named Ilse Nielsen while the Wheelers have lost their daughter Sally. In the short story by Creator/RichardMatheson, the telepathic child is a boy named Paal Nielsen while the Wheelers have lost their son David.
** In "[[Recap/TheTwilightZone1959S4E14OfLateIThinkOfCliffordville Of Late I Think of Cliffordville]]", Satan appears to William J. Feathersmith in the form of Miss Devlin. In the short story "Blind Alley" by Malcolm Jameson, Satan (most commonly called His Nibs) assumes a male form with the conventional appearance of "the vermilion anthropoid modified by barbed tail, cloven hoofs, horns and a wonderful sardonic leer."
* ''Series/TheTwilightZone1985'':
** In "[[Recap/TheTwilightZone1985S1E9 Dead Woman's Shoes]]", Maddie Duncan is possessed by the spirit of a murdered woman named Susan Montgomery when she puts on her expensive high heels. In the original episode "[[Recap/TheTwilightZone1959S3E18DeadMansShoes Dead Man's Shoes]]", the murdered gangster Dane's personality takes control of a homeless man named Nate Bledsoe when he puts on his two-tone black and white shoes.
** In "[[Recap/TheTwilightZone1985S1E16 To See the Invisible Man]]", Mitchell Chaplin meets an invisible woman who refuses to talk to him during his own sentence of invisibility. He later acknowledges her presence once he has completed his sentence. In the short story by Creator/RobertSilverberg, the other invisible person was a man.
** In "[[Recap/TheTwilightZone1985S1E23 Shadow Play]]", Adam Grant's defense attorney Erin Jacobs goes to the district attorney Mark Ritchie over her concerns that Adam may be telling the truth about all of them being characters in his [[RecurringDreams recurring nightmare]] about being executed. In the [[Recap/TheTwilightZone1959S2E26ShadowPlay original episode]], the matter was first raised by the [[AdaptationalJobChange newspaper editor]] Paul Carson.
** In "[[Recap/TheTwilightZone1985S3E16 The Cold Equations]]", the Ship's Record clerk is a woman. In the [[Literature/TheColdEquations short story]] by Tom Godwin, the clerk is a man.
[[/folder]]

* Technically all games where you can pick the gender of your PlayerCharacter feature gender flipped versions of the protagonist. No matter if you play as male or female, your character is given the same backstory, same quests, and same character arc. A good example is Creator/BioWare's ''Franchise/MassEffect'' trilogy, where Shepard is given the same last name, familial backstory, and pre-service record regardless of gender, so the male and female versions of Shepard are essentially Gender Flipped alternate versions of each other. Some games, however, like ''VideoGame/Fallout4'', avert this by making the male and female versions of the PlayerCharacter distinct. In the case of ''Fallout 4'', the male and female versions of the Sole Survivor are husband and wife. [[spoiler:Only the chosen PC survives the tutorial, and part of their motivation is tracking down their spouse's killer.]]
* ''VideoGame/SuperPrincessPeach'' gave Peach a starring role where she saves the Franchise/SuperMarioBros. from Bowser for a change, instead of the brothers setting out to rescue her as in so many previous Mario games. Also, the subplot of ''VideoGame/SuperMarioGalaxy'' appears to be a gender-flipped version of ''Literature/TheLittlePrince''.
* Dr. Julie Langford from ''VideoGame/BioShock1'' was originally a man named Holden Langford, but Ken Levine made her female to add more female characters to the game. The art subtitles still mistakenly read "Holden Langford" for every sign in her lab.
* ''VideoGame/StoryOfSeasons'': ''VideoGame/HarvestMoonBackToNature For Girls'' ([=PlayStation=]), ''More Friends of Mineral Town'' (Game Boy Advance), ''[[VideoGame/HarvestMoonAWonderfulLife Harvest Moon Another Wonderful Life]]'' ([=GameCube=]), and ''VideoGame/HarvestMoonDS Cute''. All four had official localizations, though the first one was not translated until the PSP compilation ''Boy and Girl''. Future games allow you to choose your gender at the start.
* The three ''VisualNovel/TokimekiMemorialGirlsSide'' games. The UsefulNotes/NintendoDS ports of the first two ''Girl's Side'' games also have complete fan translations.
* ''VideoGame/WarriorsOrochi'' features a female [[Literature/JourneyToTheWest Tang Sanzang]] (Sanzou Houshi). This is likely a nod to the old Koei game ''VideoGame/SaiyukiJourneyWest'', where you can choose Sanzang's gender.
* ''VideoGame/NamuAmidaButsuUtena'' where Ashuku Nyorai/Akṣobhya is inexplicably female ([[CrossdressingVoices though still]] [[Creator/YuusukeKobayashi voiced by a guy]]). She gets flipped again in the anime where she's a crossdressing guy instead.
** While the actual Mahāmayūrī is occasionally depicted as male, she is officially a female deity in Buddhist mythos. In the game, King Konjikikujaku is a dashing young man.
* In ''VideoGame/Onimusha2SamuraisDestiny'', WordOfGod states that the Yagyu Jubei who is the main character is the grandfather of ''the'' UsefulNotes/YagyuJubei. ...then ''VideoGame/OnimushaDawnOfDreams'' comes out and there's a Jubei (it's a title in the family) and she's his granddaughter... Any sign of a [[Anime/JubeiChan lovely eyepatch?]]
* ''VideoGame/{{Onmyoji|2016}}'' features a male Tamamo-no-Mae.
* ''VideoGame/PaperChase'': The English professor goes from male in the BASIC version to female in the Inform version.
* Due to the personalized nature of Personas in the ''Franchise/{{Persona}}'' series, some of the personal Personas of the playable characters have this happen to them.
** In [[VideoGame/Persona1 the first game]], [[ClassClown Hidehiko Uesugi's]] Initial Persona, Nemhain, is an [[Myth/CelticMythology Irish war goddess]], but in the [[AudioAdaptation CD Drama]], Nemhain is given a male voice.
** In the ''Innocent Sin'' half of ''VideoGame/Persona2'', [[TokenMinority Lisa Silverman's]] Initial Persona is [[Myth/ClassicalMythology Eros]]. In Greek myth, two male deities share that name, one being a love god and the other the primordial deity of procreation, but in this game, she's female.
** The ''VideoGame/Persona3'' VideogameRemake for the [[UsefulNotes/PlayStationPortable PSP]], you can play as a female protagonist. While she herself averts this trope - not only does she have a [[GenkiGirl drastically]] [[TheHeart different]] personality from her [[TheEeyore male]] [[SugarAndIcePersonality counterpart]], she also has her own set of [[RelationshipValues Social Links]] - her Initial Persona is a feminized version of [[Myth/ClassicalMythology Orpheus]], which is the same Persona as the male's. [[TroublingUnchildlikeBehavior Ken Amada's]] Initial Persona, meanwhile, is the female Nemesis, but due to its [[https://vignette.wikia.nocookie.net/megamitensei/images/e/e3/Nemesis.png/revision/latest?cb=20161019072510 oddly toyetic appearance]], it comes off as more gender neutral.
* ''VideoGame/PersonaQ2NewCinemaLabyrinth'' likes to play around this ''a lot''. Most of the movie OCs that the party encounters are Gender flipped from what they actually are, [[spoiler:as they are originally all people in Hikari's cognition given forms by Persona users who got dragged into the movies.]]
** Kamoshidaman, the superhero of his titular movie, [[spoiler:has nothing to do with the ObviouslyEvil pervert rapist teacher that he resembles. Instead, he's actually a teacher in Hikari's primary school who is seen as "absolute authority," who is a woman.]]
** Yosukesaurus, the outcast dinosaur of ''Junessic Land'', has nothing to do with Yosuke, nor is he as calm and determined as the real one. [[spoiler: He's actually Hikari in secondary school who was being isolated by her friends for having different opinions about dealing with bullied students.]]
** The Overseer, resembling the [[spoiler:seemingly]] friendly and punny chairman of S.E.E.S, has no relation to the real thing. [[spoiler:It's actually a hybrid cognition of Hikari's [[EducationMama Education Relatives]] who destroyed her completely by suggesting that she should get a good resume then a "normal" office worker job instead of letting her become a movie director.]]
** The BigBad [[spoiler:Nagi, actually the Mesopotamian God of justice and storms "Enlil" is a woman, even in her OneWingedAngel form where she was clearly masculine. The original god is actually a man.]]
* ''VideoGame/FinalFantasyXIII'':
** Lightning was billed as a DistaffCounterpart to ''VideoGame/FinalFantasyVII''[='=]s Cloud Strife. This got hilarious when fans of the series, after decades of extremely pretty and androgynous heroes, were all too ready to complain that Lightning was "just another girl-faced guy". Until they found out that she actually ''was'' a girl. In fact, Lightning being [[{{Bifauxnen}} mistaken for a pretty boy]] is almost a RunningGag in the games themselves, not helped that Square Enix once used her to model in a men's fashion magazine.
** Fang from the same game was initially conceived as a sexy male character, but eventually became a sexy female character (letting them desexualise Lightning, which they wanted to do). As a result, she ended up [[MasculineGirlFeminineBoy subverting the usual gender roles of]] ''Franchise/FinalFantasy'', and became quite popular as a result. Especially notable is that Fang's gender flip had little, if any, effect on her [[LesYay relationship with Vanille]].
* ''VideoGame/SengokuBasara'' features a gender-flipped Saika Magoichi. However, this is subverted in that it could be any woman who has taken the title 'Saika Magoichi' to lead the Saika mercs. The real life Suzuki Shigehide (the best known Saika Magoichi) is said to have had a wife/sister/daughter, and she could very well be any one of them.
* In ''VideoGame/{{Tekken}}'', Kunimitsu was initially a palette swap of Yoshimitsu, but in the second game, was [=gender flipped=] and given a mostly-new moveset.
* ''VideoGame/AkaSeka'' features a male Creator/MurasakiShikibu.
* In ''VideoGame/BionicCommando Rearmed'', Hal was replaced by Haley.
* Samus from ''Franchise/{{Metroid}}'' was (like Aliens above) gender-neutral until the very end where the designers decided to add a twist to the end. The twist? Create a new trope! SamusIsAGirl indeed.
* One of the playable characters of ''[[VideoGame/OtogiMythOfDemons Otogi 2: Immortal Warriors]]'' is the cold and stoic [[KungFuWizard imperial sorceress]] Seimei, a major protagonist and spiritual guide who's based on the real-life man and legendary Japanese folk-figure Abe no Seimei.
* ''VideoGame/ChoiceOfGames'': The game ''Choice of Broadsides'' allows you to play an entire ''genre'' under Gender Flipped conditions: rather than force the protagonist to be male, the player has the option of changing the setting to being [[WoodenShipsAndIronMen Wooden Ships and Iron]] '''Women'''. ''[[VideoGame/AffairsOfTheCourt Choice of Romance]]'' is somewhat similar, but not quite as pronounced -- the game culture is a bisexual one. The player's choice of character sex and sexual orientation determines the sex of his/her suitors, but the suitors' characters remain the same.
* ''VideoGame/KirbyStarAllies'': Longtime recurring enemy [[NeatFreak Broom Hatter]], who had previously been referred to as female up until this point, is suddenly referred to with ''male'' pronouns.
* In the original ''VideoGame/MonkeyIsland2LeChucksRevenge'', when Guybrush calls the Creator/LucasArts Help Desk (then [=LucasFilm=] Games Help Desk) on Dinky Island, the phone operator on the other end of the phone appears near him... and it appears to be [[GenderBlenderName a woman named Chester]]! In the redrawn Special Edition, however, Chester the phone operator is now a man. Interestingly, both characters can be found in the Special Edition version, with female Chester appearing in Classic mode and male Chester appearing in the high-definition mode, and both characters even have unique voice actors.
* ''The Flower Shop: Summer in Fairbrook'' was a 2010 indie game about [[SimulationGame gardening]] and [[DatingSim relationships]]. It was followed up with a reverse harem game called ''Winter in Fairbrook'' the next year.
* The main games in Red Entertainment's ''VideoGame/SakuraWars'' franchise all feature male main characters.
** Between 2010 and 2011, the same company created a similar two-part [=PS2=] and PSP series called ''Scared Rider Zechs'', with a female lead and a harem of men.
** Also, a manga spinoff called ''Sakura Wars Kanadegumi'' began publication in 2011. It's a story about one girl and several guys that take place in the Sakura Wars universe.
* The ''Franchise/ShinMegamiTensei'' games have LouisCypher as a recurring character. ''VideoGame/ShinMegamiTenseiStrangeJourney'' has Louisa Ferre instead.
* ''Strange Journey'' gets even stranger: everyone's favorite [[GagPenis penis demon]], Mara, is '''female''' for a change. Yes, she's ''still'' a penis.
* In the original version of Creator/LucasArts' 1990 fantasy adventure game ''VideoGame/{{Loom}}'', the main villain is Chaos, the King of the Dead. As an inhuman undead specter, Chaos' gender is determined only by the other characters' dialogue--and in the original release, they refer to ''him'' and ''he''. In the rewritten talkie PC CD version, however, the dialogue is changed so Chaos becomes ''she''. (This may have occurred in part because Chaos' design was based on the look of [[WesternAnimation/SleepingBeauty Maleficent]].)
* Milk, the hero of the NES game ''Nuts & Milk'', was female in the earlier Japanese PC versions.
* The Rip Van Fish are female in ''VideoGame/{{Something}}'' because they are [[PinkMeansFeminine pink]] and their [[CatchingSomeZs Zs]] are replaced with [[SayItWithHearts hearts]]. They only show up in Only Water Level.
* ''VideoGame/SpiderManShatteredDimensions'' has a female version of ComicBook/DoctorOctopus as the BigBad of the ComicBook/SpiderMan2099 portion of the game. Also, counts as a [[TwoferTokenMinority Twofer]] since she is of Indian descent.
* The main antagonist of ''VideoGame/SpiderManMilesMorales'' is the Tinkerer, who is reimagined as a young woman instead of the elderly man from the comics.
* One dad [[http://kotaku.com/5958918/father-hacks-zelda-for-his-daughter-makes-link-a-girl hacked]] a copy of ''VideoGame/TheLegendOfZeldaTheWindWaker'' to turn Link into a girl by changing all the gendered pronouns.
* ''Franchise/TombRaider'' star Lara Croft was originally envisioned as a man, but the character was changed into a woman because the developers felt that the character would be too similar to Franchise/IndianaJones.
* The NES (and most well-known) version of ''VideoGame/{{Uninvited}}'' changed the protagonist's younger brother into an older sister who otherwise fills the same role.
* ''VideoGame/MegaManBattleNetwork's'' [[AlternateUniverse reimagining]] of [[VideoGame/MegaMan4 Ring Man]] is female.
* ''VideoGame/ShovelKnight'' added Body Swap Mode as part of the Treasure Trove update, allowing players to switch the genders of whichever major characters they choose, updating the sprites and dialog to match. The only thing it doesn't affect is the visuals of the intro cutscene, since the developers would have needed to create versions of the pixel art for every possible permutation of the main cast's genders.
* ''VideoGame/DefenseOfTheAncients'' had Tresdin the Legion Commander: a mustachioed and [[FantasticRacism racist]] [[ExactlyWhatitSaysOntheTin commander of a legion.]] In ''VideoGame/Dota2'' Tresdin has been retooled into a woman, is still a commander of a legion, and the racism is toned down but she is still aggressively adamant in her distrust of non-humans, ''especially'' demons after [[DoomedHometown Stonehall.]]
* In the NES version and one of the US arcade versions of the Capcom shoot-'em-up ''Legendary Wings'', the two main characters of Michelle Heart and Kevin Walker are replaced by nameless angels, both of them male.
* The Famicom game ''VideoGame/FinalMission'' featured two male commandos as the main characters. When the game was localized for the NES under the title of ''[[VideoGame/SpecialCyberneticAttackTeam S.C.A.T.: Special Cybernetic Attack Team]]'', one of them became female.
* ''VideoGame/BatmanArkhamOrigins'' has a female version of Copperhead as one of the boss characters. Batman even lampshades this by stating that all of the data he had thus far collected in relation to Copperhead indicated a man.
* [[VideoGame/SpiderManTrilogy The tie-in game to]] ''Film/SpiderMan3'' does this to Dr. Farley Stillwell, making him female.
* The main character of the book ''Literature/{{Bedlam}}'' is Ross Baker (whose gamertag is Bedlam), a man. The main character of its video game adaptation, ''VideoGame/{{Bedlam}}'', is Heather Quinn (whose gamertag was Athena), a woman (though the game's still named after the original protagonist). WordOfGod says he wanted a woman in the game because so few FPS protagonists are women, and says in retrospect that he should have made the main character of the book a woman, too.
* ''VideoGame/{{Loved}}'' does this to ''the player''. The voice asks you whether you're a man or a woman; if you respond "man," the voice refers to you as "girl" for the rest of the game, and if you answer "woman," it refers to you as "boy."
* There's a part in ''VideoGame/TheLegendOfHeroesTrailsInTheSky'' where the characters put on a SchoolPlay at the Academy. The students stage the classic play "The Madrigal of White Magnolias" but with gender-swapped casting: thus Estelle and Kloe play the dueling knights while Joshua is cajoled into playing the role of the princess.
* The ''VideoGame/{{Bomberman}}'' series has the arcade spinoff ''VideoGame/BomberGirl'', focusing on an all-female ([[AdaptationSpeciesChange and human]]) cast of playable characters. The main two Bomber characters are even flips of White Bomberman (Shiro) and Black Bomberman (Kuro).
* The ''Franchise/ScoobyDoo'' video game ''VideoGame/ScoobyDooWhosWatchingWho'' features two suspects who are female versions of male villains from ''WesternAnimation/ScoobyDooWhereAreYou'':
** One of the three suspects for the true identity of the Space Kook is Henrietta Bascombe, who is based on Henry Bascombe, the true identity of the Space Kook in the original series episode "Spooky Space Kook".
** In the Oceanland level, one of the suspects for the true identity of the Ghost of Redbeard is Professor Alicia Wayne. She is loosely based on Professor Wayne from the original series episode "Scooby's Night with a Frozen Fright".
* ''VideoGame/HeroesOfTheStorm'': Two heroes have this. The Barbarian from ''VideoGame/DiabloIII'' is almost always marketed as the male one, but the [=HotS=] team opted to create the female character Sonya for the barbarian representative. Likewise, the Siege Tank unit was male in both ''VideoGame/StarCraft'' games. Heroes instead use a female CanonForeigner named Sgt. Hammer.
* The ''VideoGame/KunioKun'' spinoff ''VideoGame/RiverCityGirls'' has Misako and Kyoko rushing off to rescue Kunio and Riki.
* In ''VideoGame/WarcraftIII: [[VideoGameRemake Reforged]]'', the Demon Hunter and the Death Knight in skirmishes can be optionally played as female variants, with voice lines to boot. Some of the creeps were changed from male to female, particularly the [[OurCentaursAreDifferent centaurs]] and [[FaunsAndSatyrs satyrs]]. Count as GuysSmashGirlsShoot since the swapped gender of those units were archers and spellcasters.
* In most dubs of ''VideoGame/DoomEternal'', the computer voice that greets the Doom Slayer in Urdak is female. In the Polish dub, the voice is male.
* When ''VideoGame/UltimaIV'' was ported to the NES, the female tinker Julia was changed to the male Julius.
* Much like in ''Film/AntManAndTheWasp'', ''VideoGame/IronManVR'' presents Ghost as a [[RaceLift black]] woman instead of a white man.

[[folder:Western Animation]]
* In ''WesternAnimation/TheAmazingWorldOfGumball'', when Nicole, her children and Larry are trying to chase Richard to prevent him from delivering the next pizza in time, so that Larry can fire him and prevent the fabric of the universe from being completely torn apart, the more they get close to him, the more they are affected by his universe-tearing power. In a brief instance, they become subjected to a gender flip, among other reality distortions such as a body swap or a realistic rendering of their cartoony selves.
* The ''WesternAnimation/AdventureTime'' "Fionna and Cake" episodes (one per season since the fourth season) do this to pretty much every character in the show (except for the canonically agender BMO), including the theme song singer.
* In ''WesternAnimation/TheAnimalsOfFarthingWood'' animated series, Owl, Weasel, Kestrel and Adder, who were males in the books, were changed to females. Confusingly, Kestrel has male plumage.
** Due to the fact that Adder, Weasel and Owl were females in the TV series, their love interests (who were females in the books) got their genders-swapped too, with them becoming males.
* ''WesternAnimation/{{Animaniacs}}'':
** The creators couldn't get the rights to use Screwy Squirrel from ''WesternAnimation/TexAveryMGMCartoons'', and thus, the equally violent Slappy Squirrel was born.
** The Warners were also originally three brothers, but the third was sort of uninteresting, so she became a girl to add something new.
* ''WesternAnimation/AvatarTheLastAirbender'':
** Fans often joke that the roles of the EvilOverlord's son and daughter on the EvilOverlordList are gender flipped with Zuko and Azula. [[AllThereInTheManual The Nick website]] also suggests Ozai and Zuko are a rare Gender Flip of the FairestOfThemAll trope.
** The series also has two [[WhatCouldHaveBeen developmental]] gender flips: Toph and Azula both started as ''male'' characters (the latter being called "Prince Azul", and initially having a much smaller part that didn't come up until the end). The former gets a reference in [[WhoWouldWantToWatchUs The Ember Island Players]], among many, many other in-jokes. The original male design for Toph went on to be reused for Avatar Roku's Earthbending teacher.
* Franchise/{{Barbie}} gets some meatier roles via Gender Flip in:
** ''The Princess and the Pauper'', a girls' video based on {{Franchise/Barbie}} dolls.
** ''WesternAnimation/BarbieAndTheThreeMusketeers'' (Barbie as an ActionGirl!)
** ''Barbie in Literature/AChristmasCarol'' (Ebenezer Scrooge is now an Victorian-era opera diva named Eden Starling)
* ''WesternAnimation/TheBatman''
** Gotham mayor Marion Grange changed to a male, despite the comic version of the character being a woman. This was mostly so that the creators could cast Creator/AdamWest in the part.
** Vulture of the Terrible Trio was made into a woman [[AffirmativeActionGirl due to the comic book version of the group consisting of nothing but men]].
* In the original pilot of ''WesternAnimation/BobsBurgers'' Tina was a boy named Daniel. This is particularly humourous considering the voices and personalities of both characters are identical.
* In-universe example: The ''WesternAnimation/DangerMouse'' episode "A Loo to a Kill" is set during the filming of a ''Danger Mouse'' movie, in which DM plays himself, and Penfold is played by Scarlett Johamster (and PromotedToLoveInterest).
* In ''WesternAnimation/DCSuperHeroGirls'', Comicbook/HarleyQuinn's pet hyenas are girls named [[Series/ILoveLucy Lucy and Ethel]] instead of boys named [[Creator/AbbottAndCostello Bud and Lou]].
* A particularly demented example occurs in ''WesternAnimation/DrawnTogether'' on the episode "A [[VerySpecialEpisode Very Special]] Drawn Together Afterschool Special" where the characters, in an attempt to help Xandir prepare for revealing his homosexuality to his parents, role play as Xandir's parents (among other random roles). Eventually even this fake family has to see a therapist (Woldoor), who suggests that said role playing family role play yet again. This ends with Captain Hero being a meek, feminine housewife, Toot being a homophobic blue-collar father, and Xandir becoming a prostitute for Japanese businessmen.
* In ''WesternAnimation/FantasticFourTheAnimatedSeries'', Lavinia Forbes, the Baxter Building landlady who doesn't much like having a superhero team in her building but can't evict them, is a flip of Walter Collins, the Baxter Building landlord from early ''ComicBook/FantasticFour'' comics, who doesn't much like having a superhero team in his building but can't evict them.
* In the 90s cartoon version of ''[[WesternAnimation/FlashGordon1996 Flash Gordon]]'', Flash's ally Prince Thun of the Lion People became Princess Thundar.
* ''WesternAnimation/{{Gargoyles}}'' was originally going to have Broadway as a female, but ExecutiveMeddling didn't like the idea of [[DoubleStandard an overweight female protagonist]]. It's worth noting that the clan was also originally going to be led by a female named Dakota, but she was considered uninteresting, so they reimagined her as [[BigBad Demona]] and created Goliath instead.
* In ''WesternAnimation/GerryAndersonsNewCaptainScarlet'', Seymour Griffiths (CodeName: Lt. Green) is replaced by Serena Lewis (also codenamed Lt. Green).
* ''WesternAnimation/GIJoeResolute'' reimagined Dial Tone as a woman. On the subject as to why, Creator/WarrenEllis, who wrote it, [[http://www.warrenellis.com/?p=7227 said]] that Creator/{{Hasbro}} insisted a random tech he gave a lot of dialogue to be a named Joe and literally said that he picked Dial Tone "because {{it amused me}}."
* ''WesternAnimation/HappilyEverAfterFairyTalesForEveryChild'' occasionally did this to the characters, along with changing the stories to be more multiracial than the typically European originals. For example Literature/ThePrinceAndThePauper became "The Princess and the Pauper".
* Ram Man from ''WesternAnimation/HeManAndTheMastersOfTheUniverse1983'' is reimagined into Ram ''Ma'am'' in ''WesternAnimation/HeManAndTheMastersOfTheUniverse2021''. Mosquitor is likewise remade into Mos'quita-ra.
* Green Ghost and Shrinking Ray are both women in ''WesternAnimation/Invincible2021'', when they were male in [[ComicBook/{{Invincible}} the source comics]]. The latter had her name changed to the more feminine Shrinking Ra'''e''' to match.
* ''WesternAnimation/IronManArmoredAdventures'' depicts the Mad Thinker, a middle-aged or elderly male in the comics, as a teenage girl.
* In the original ''WesternAnimation/InspectorGadget'', MAD Cat was male. In [[WesternAnimation/InspectorGadget2015 the 2015 reboot]], MAD Cat is female.
* Used heavily in ''WesternAnimation/{{Jellystone}}'', switching numerous characters who were originally male to female. Among them are WesternAnimation/{{Jabberjaw}}, WesternAnimation/{{Augie Doggie|And Doggie Daddy}}, WesternAnimation/SquiddlyDiddly, Brain, Choo-Choo, & Spook (now Spooky) of WesternAnimation/TopCat, WesternAnimation/LoopyDeLoop, and Yappee of Yippee, Yappee, and Yahooey.
* ''WesternAnimation/JohnnyTest'': One episode had Johnny get into a ShowWithinAShow involving "An annoying younger sibling who pesters his twin ''brother'' mad scientists for experiments". None of the characters can place the similarities. The episode ends with Johnny and his Expy hanging out while both sets of twins have a double date.
* In the early planning stages of the ''WesternAnimation/JusticeLeague'' animated series, a female version of ComicBook/{{Cyborg}} was supposed to have been part of the main cast. [[https://www.youtube.com/watch?v=aCVKlb5hqV4 Test footage of her even exists.]] The character design later appeared in the comics as Cyborg's EvilCounterpart and niece of his LoveInterest.
* In ''WesternAnimation/JusticeLeague Unlimited'', the second Queen from the Royal Flush Gang is a male {{Crossdresser}} rather than a woman. Not quite a straight example, though, since the Gang itself tends to have a revolving roster... For that matter, in both versions of the RFG seen in the series, we have Ace (the only carryover member) as a young preteen girl; in all comics before this and ''most'' adaptations (including distant-sequel ''WesternAnimation/BatmanBeyond''), Ace is a male character (and is often depicted as a cyborg or android with SuperStrength).
* Little Miss Scatterbrain and Little Miss Stubborn have become Mr. Scatterbrain and Mr. Stubborn in ''WesternAnimation/TheMrMenShow''.
* ''WesternAnimation/MyAdventuresWithSuperman'':
** In the comics, the Newsboy Legion was an entirely male group. Here, members Walter "Flippa Dippa" Johnson, Anthony "Gabby" Rodriguez, and Patrick "Scrapper" [=MacGuire=] are reimagined as the now female Flip Johnson, Gaby, and Patti, respectively, resulting in the team's name being changed to the Newskid Legion as well.
** Male comics character Ron Troupe has been changed to the female Ronnie Troupe for this show.
** Heat Wave is male in the comics, but appears as a woman in this show. While there ''is'' a female version of Heat Wave in the comics, the version seen in the show is meant to be an adaptation of the Mick Rory incarnation of the character.
** An in-universe case of this trope occurs with the appearance of the [[AllianceOfAlternates League of Lois Lanes]], which includes a male alternate of Lois named Lewis Lane and a female alternate of Jimmy named Jalana Olsen.
* ''WesternAnimation/MyLittlePonyFriendshipIsMagic'' did this to the [[Franchise/MyLittlePony Gen 3]] pony Star Swirl, who was mentioned but not seen until his appearance in Season 7, and called Star Swirl the Bearded.
* ''WesternAnimation/NakedMoleRatGetsDressedTheRockSpecial'' replaces the mole rats' patriarch Grand-pah from the original book with a matriarch named Grand-mah.
* In ''WesternAnimation/TheNewBatmanAdventures'', Calendar Man's counterpart is a former model called Calendar Girl (name aside, though, she's a very different character).
* When they are introduced in the second season of ''WesternAnimation/WinxClub'', the Pixies were all female. But in the SpinOff series ''WesternAnimation/PopPixie'' (that is an AlternateUniverse), some of them who had significant roles in the original series (Digit, Livy, Zing, and Jolly) have had gender alterations and are male now.
** It is also confirmed by the creator that Helia was supposed to be a girl, hence why he has a female name. It's likely he was supposed to be the new 6th Winx fairy (as well as Flora's best friend), but his gender was changed so he could become a love interest.
* The animated adaptation of the ''Literature/{{Redwall}}'' book ''Martin the Warrior'' changed the gender of the hedgehog character Pallum from male to female. This was because it was thought there were not enough female characters in the main cast.
* Zig-zagged in ''WesternAnimation/RiseOfTheTeenageMutantNinjaTurtles'': The GrandFinale appears to reveal that The Foot Recruit, who's female, is a gender flipped version of [[spoiler: Casey Jones]], but the real deal debuts in the BigDamnMovie, enlisting the Turtles' help in preventing his BadFuture from coming to pass who reveals that the former is his mother.
* In ''Westernanimation/RobinHoodMischiefInSherwood'', the role of Will Scarlet is filled by a girl named Scarlett in order to avert TheSmurfettePrinciple.
* The CGI ''WesternAnimation/{{Rupert}}'' cartoon flipped Pong Ping and Ferdy Fox into females, renaming them "Ping Pong" and "Frieda" respectively.
* ''Sad Cat'', an early (and forgotten) Creator/RalphBakshi character, was a gender-flipped version of "Cinderella" (with evil step-brothers instead of evil step-sisters, and the fairy godmother being a male "Gadmouse"), a rare female-to-male example of this trope.
* ''WesternAnimation/SherlockHolmesInTheTwentySecondCentury'' has Inspector Lestrade as a female (she's a descendant of the male Lestrade from the original Literature/SherlockHolmes stories, and also a major fan of the master detective in general).
* When ''WesternAnimation/TheSimpsons'' puts their cast members in another story to parody the original, occasionally Lisa will be given a role that was originally male. For instance, Lisa was given equivalent roles for Franchise/SherlockHolmes, Johnny "Connie" Appleseed, and Film/{{Amadeus}} (as Sally Eri).
* Implied with [[WesternAnimation/TheJungleBook1967 Kaa]] from the animated short ''WesternAnimation/WelcomeToTheClub'', she has a female voice, presumably with the intent of homaging Creator/ScarlettJohansson's performance in [[Film/TheJungleBook2016 the 2016 film]].
* Azrael, the cat from ''WesternAnimation/TheSmurfs1981'' was female in the comic books, but is male in the TV show, later comics, and [[Film/TheSmurfs live-action movie]].
* Despite not appearing in ''WesternAnimation/SheRaPrincessOfPower'' aside from being mentioned in the series bible and relegated to a toyline-exclusive character, Double Trouble (who is female) is gender flipped to non-binary for ''WesternAnimation/SheRaAndThePrincessesOfPower'' along with using "they/them" pronouns.
** Additionally, the [[AnimalMotifs peacock-themed]] seer Peekablue is male in the reboot, thus averting [[PeacockGirl his original-series counterpart]]'s AnimalGenderBender. He is appropriately a {{Bishonen}}[[spoiler:...at least, if Double Trouble's impersonation of him is accurate; the real Peekablue never actually appears]].
** The Star Sisters also became the Star Siblings, with Jewelstar being male. Interestingly enough, the Star ''Sisters'' and Prin''cess'' Peekablue were namedropped in the "Princess Prom" episode (though they didn't appear on-screen), and Double Trouble was visible in some background shots of the same episode.
* ''WesternAnimation/SpideyAndHisAmazingFriends'' changes Dr. Octopus into a girl.
* ''WesternAnimation/TransformersAnimated'':
** Changed the character of Red Alert from [[Anime/TransformersArmada The]] [[Anime/TransformersEnergon Unicron]] [[Anime/TransformersCybertron Trilogy]] from a male to a female for their own version of Red Alert. In fact, they originally wanted [[TheMedic Ratchet]] to be female and have Red Alert's name, but the final version of the show changed Ratchet back into a male, and made Red Alert a separate character.
*** Interestingly, Ratchet was intended to be female in the original [[ComicBook/TheTransformersMarvel Marvel comics]]. But ExecutiveMeddling made him male to the Transformers toyline's "no gender" rule and being for boys.
** Also, the comic story "The Stunticon Job" depicts the ''Animated'' version of Drag Strip as a femme.
* ''WesternAnimation/TransformersCyberverse'':
** Cosmos is reinterpreted as female rather than male.
** This continuity's version of Swoop, introduced in the TV movie ''The Immobilizers'', is female when all prior incarnations of the Dinobot were male.
** A few of the Seekers had their genders changed as well. Nova Storm and Skywarp were male in ''G1'' and female in ''Cyberverse''. Acid Storm was supposed to follow suit but was animated with both the male and female Seeker body types so the writers decided to make them non-binary.
** The Quintesson Judge has five faces and normally all faces are presented as male while here two are women whilst the other three are men.
** Clobber's exisence is due to this. She's clearly designed as a female version of the ''Animated'' character Lugnut, and in fact was intended to be, but Hasbro executives forced the show's crew to rename and make her a separate character.
* ''WesternAnimation/TransformersEarthSpark'':
** Just like in ''Cyberverse'', Skywarp and Nova Storm appear as female robots.
** The Decepticon Cassette Frenzy is also female in this continuity.
* In The Mondo TV version of ''WesternAnimation/TheTrashPack'', as a way to give a gender balance to the main Trashies, Scum Gum, Scabby Cat, and Sour Snail were made female, as opposed to the male pronouns they were given in the toyline. When Scum Gum and Sour Snail returned in [[WebAnimation/TheTrashPack the webseries]], they were reverted back to male.
* The "Spider-Verse" arc in ''WesternAnimation/UltimateSpiderMan2012'' introduces Petra Parker, a.k.a. Spider-Girl, a teen girl version of Peter Parker from an alternate universe. Petra's Earth also contains female versions of ComicBook/NickFury (Nicole Fury), Harry Osborn (Harriet Osborn), J. Jonah Jameson (J. Joanne Jameson) and Norman Osborn (Norma Osborn).
* In ''WesternAnimation/VoltronLegendaryDefender'', it's revealed that [[spoiler:the series' version of Pidge is really a girl named Katie Holt. She's pulling a SweetPollyOliver to join the Galactic Garrison and locate her missing brother, since she was banned from their facility for breaking in one too many times.]]
* The cartoon version of ''WesternAnimation/WatershipDown'' has the book character Blackberry made from a buck to a doe. Many fans were displeased about this, since half the plot of the original is about the fact that they ''need'' does to establish a successful warren.
* ''WesternAnimation/WolverineAndTheXMen2009'':
** Arclight, a woman in the comics, was remade into a man. WordOfGod is that they didn't feel comfortable having Cyclops violently confront a woman while on a warpath as he did to the show's Arclight when [[spoiler:he asked about Sinister's location, believing he has Jean.]]
** Master Mold is female. Of course, Master Mold has always been a robot that gave birth to other robots, but he was previously referred to as male anyway.
* Spyke from ''WesternAnimation/XMenEvolution'' seems like a [[RaceLift black]], [[SpearCounterpart male]] version of Marrow, but WordOfGod is that they was a complete coincidence. The show's creator claimed he had never heard of Marrow prior to working on the show, which is not too implausible given the character's relative obscurity.
* In ''WesternAnimation/YoungJustice2010'':
** Red Inferno and Red Torpedo have their genders flipped from the original comics. This is because the show [[RetroactiveLegacy establishes that the two were originally]] the [[UsefulNotes/TheGoldenAgeOfComicBooks Golden Age]] heroes Red Torpedo and Firebrand, and thus their genders needed to match their 40's counterparts (Greg even commented on this, including his confusion at the ''original'' change).
** Asami "Sam" Koizumi is a female version of [[CaptainEthnic Samurai]] from ''{{WesternAnimation/Superfriends}}''.
** The Newsboy Legion is reimagined as the News''girl'' Legion, with Tommy Thompkins changed to Tommi Thompkins, Tony "Big Words" Rodriguez to Antonia "Big Words" Rodriguez and John "Gabby" Gabrielli to Gabi Gabrielli.
** Rictus is also changed from a man to a woman.
** The Child from ''ComicBook/AmethystPrincessOfGemworld'' appears in the fourth season, but with their human form now that of a little girl rather than a boy.
* In the original ''WesternAnimation/PetAlien'' toyline, [[MultipleHeadCase Shank and Dank]] were both male. In the show, Shank is instead female while Dank stays male.
[[/folder]]

* ''VideoGame/ChoiceOfGames'': The game ''Choice of Broadsides'' allows you to play an entire ''genre'' under Gender Flipped conditions: rather than force the protagonist to be male, the player has the option of changing the setting to being [[WoodenShipsAndIronMen Wooden Ships and Iron]] '''Women'''. ''Choice of Romance'' is somewhat similar, but not quite as pronounced -- the game culture is a bisexual one. The player's choice of character sex and sexual orientation determines the sex of his/her suitors, but the suitors' characters remain the same.

* Creator/ChoiceOfGames' ''Choice of Broadsides'' game allows you to play an entire ''genre'' under Gender Flipped conditions: rather than force the protagonist to be male, the player has the option of changing the setting to being [[WoodenShipsAndIronMen Wooden Ships and Iron]] '''Women'''. ''Choice of Romance'' is somewhat similar, but not quite as pronounced -- the game culture is a bisexual one. The player's choice of character sex and sexual orientation determines the sex of his/her suitors, but the suitors' characters remain the same.

* Green Ghost and Shrinking Ray are both women in ''WesternAnimation/Invincible2021'', when they were male in [[ComicBook/{{Invincible}} the source comics]].