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* In Literature/ThereIsNoAntimemeticsDivision, The Antimemetics Division, as well as numerous other similar agencies, have been locked in one of these for decades, possibly centuries, regarding SCP-3125. [[spoiler: Every time they become aware of its existence and fail to contain that knowledge, it attacks and destroys everyone even tangentially connected to this awareness]]. Once this became understood, deliberate, and carefully managed amnesia of it was their only defense.
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* In Literature/ThereIsNoAntimemeticsDivision, The ''Literature/ThereIsNoAntimemeticsDivision'', the Antimemetics Division, as well as numerous other similar agencies, have been locked in one of these for decades, possibly centuries, regarding SCP-3125. [[spoiler: Every time they become aware of its existence and fail to contain that knowledge, it attacks and destroys everyone even tangentially connected to this awareness]]. Once this became understood, deliberate, and carefully managed amnesia of it was their only defense.
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* This is the driving force behind the plot of ''Film/BeforeIGoToSleep''.
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* ''VideoGame/{{Rengoku}}'': It's heavily implied that being defeated by Gryphus on the last floor also completely resets the ADAM, as floor masters react to Gram as if they've fought countless times already. It's intentional in both games, as [[spoiler:in the first game Deucalion awaits an ADAM with enough will to break the cycle, while in the second game Beartice waits from Gram to recover his memories.]]
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* ''VideoGame/{{Rengoku}}'': It's heavily implied that being defeated by Gryphus on the last floor also completely resets the ADAM, as floor masters react to Gram as if they've fought countless times already. It's intentional in both games, as [[spoiler:in the first game Deucalion awaits an ADAM with enough will to break the cycle, while in the second game Beartice Beatrice waits from Gram to recover his memories.]]
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** The Silents (being creatures that you immediately forget the second you're not looking at them) induce this in their victims, with the very fact of their existence being the constantly forgotten revelation in their first episode. The problem of forgetting them cannot easily be solved; even pictures of them get forgotten instantly and spoken information about them fades fairly quickly (though not instantly), but people can leave themselves messages and warnings about them, and thus make themselves aware of their existence even when they can't actually remember them.
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** The Silents Silence (being creatures that you immediately forget the second you're not looking at them) induce this in their victims, with the very fact of their existence being the constantly forgotten revelation in their first episode. The problem of forgetting them cannot easily be solved; even pictures of them get forgotten instantly and spoken information about them fades fairly quickly (though not instantly), but people can leave themselves messages and warnings about them, and thus make themselves aware of their existence even when they can't actually remember them.
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* On ''WesternAnimation/TheVentureBrothers'', in the fourth season, Hank and Dean keep discovering that SPHINX's secret base is in an annex of the Venture compound, and Brock keeps having to erase their memories. After a while, Brock gives up because it isn't worth the effort and it seems to be giving the boys some whacky brain damage where they can't properly describe the color pink.
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* On ''WesternAnimation/TheVentureBrothers'', in the fourth season, Hank and Dean keep discovering that SPHINX's secret base is in an annex of the Venture compound, and Brock keeps having to erase their memories. After a while, Brock gives up because it isn't worth the effort and it seems to be giving the boys some whacky wacky brain damage where they can't properly describe the color pink.
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* ''ComicBook/JusticeSocietyOfAmerica'': Professor Malachi Zee is repeatedly getting murdered or attacked by his lab assistant Per Degaton to steal his time machine. Once the JSA fixes whatever temporal change Degaton tried to do, everyone forgets and Degaton is back to cleaning test tubes. As a result of the constant conflict between them, Zee continues to work on his time machine, believing that it has failed to work thus far (not remembering it was simply hijacked and its effects have been erased from history).
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* ''Fanfic/StepRightInAndStartAgain'': Every time that the time loop that Starlight is trapped in resets, her memories of the previous iteration vanish as well -- she begins each new instance believing that she just gave up her plans for revenge and is about to be judged by Twilight for her crimes, leading her to suffer increasing panic and confusion as the world changes more and more around her.
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* ''Fanfic/StepRightInAndStartAgain'': Every time that the time loop that As a side-effect of messing with temporal magic, Starlight is trapped in resets, a personal loop where she wakes up each morning with her memories of the previous iteration vanish as well -- she begins wiped, beginning each new instance believing that she just gave up her plans for revenge and is about to be judged by Twilight for her crimes, leading her to suffer increasing panic and confusion as the world changes more and more around her.her. The other side effect is that she's now becoming TheAgeless, meaning that [[spoiler:she's still stuck in the loop even after the NaturalEndOfTime]].
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* The short horror story ''Literature/CaptainsLog'' reveals that [[spoiler:this is why AliensStealCattle - the aliens have anterograde amnesia and are biologically immortal, so they've spend thousands of years doing the same things over and over again]].
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** The episode "Father's Daze" has Stan dissatisfied with the Father's Day celebration the rest of the family set up, so Stan erases their memories so they can try Father's Day again. And again. And again and again and again ...
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* Done in the ''ComicBook/AstroCity'' story "Her Dark Plastic Roots". Beautie, a RobotSuperhero based on a fashion doll, is unsatisfied because she doesn't know her own origins, so she begins to investigate the matter. Beautie eventually discovers she was created by Elaine Girbachs, the daughter of [[GadgeteerGenius Dr. Gearbox]], but he denounces Beautie because he believed engineering and math aren't fields for girls. Ashamed, Elaine tearfully ordered Beautie to leave and [[ExactWords forget forever]]. When Beautie confronts Elaine in the present day, she orders Beautie to leave again... and it turns out that this happens every few years as Beautie's directive weakens until she re-visits Elaine again and again and again.
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* Done in the ''ComicBook/AstroCity'' story "Her Dark Plastic Roots". Beautie, a RobotSuperhero based on a fashion doll, is unsatisfied because she doesn't know her own origins, so she begins to investigate the matter. Beautie eventually discovers she [[spoiler:she was created by Elaine Girbachs, the daughter of [[GadgeteerGenius Dr. Gearbox]], but he denounces Beautie because he believed engineering and math aren't fields for girls. Ashamed, Elaine tearfully ordered Beautie to leave and [[ExactWords forget forever]]. When Beautie confronts Elaine in the present day, she orders Beautie to leave again... and it turns out that this happens every few years as Beautie's directive weakens until she re-visits Elaine again and again and again.again]].
