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* Not to say I don’t like the alternate ending but it seems to be that there is a conflict between the alternate ending and the rest of the movie. Robert tells Anna that the virus originally killed 90% of the human population (5.4 billion) leaving less than 1% that were immune (12 million) and the rest (588 million) turned into the Darkseekers and then slaughtered most of the immune, but doesn’t this contradict with how in the alternate ending the Darkseekers were actually intelligent and had a capacity for empathy because the leader simply wanted his mate back and left peacefully once Neville returned her, thus leading to Neville’s realization that to them ''he'' is the monster, but how can that be if they killed most of the immune and will pursue and attack a human on sight even if said human is simply trying to escape such as when Neville rescues Sam when she pursued the deer into the Darkseeker-occupied building? Ironically this seems to make the theatrical FocusGroupEnding more consistent with the rest of the movie.
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* Not to say I don’t like the alternate ending but it seems to be that there is a conflict between the alternate ending and the rest of the movie. Robert tells Anna that the virus originally killed 90% of the human population (5.4 billion) leaving less than 1% that were immune (12 million) and the rest (588 million) turned into the Darkseekers and then slaughtered most of the immune, but doesn’t this contradict with how in the alternate ending the Darkseekers were actually intelligent and had a capacity for empathy because the leader simply wanted his mate back and left peacefully once Neville returned her, thus leading to Neville’s realization that to them ''he'' is the monster, but how can that be if they killed most of the immune and will pursue and attack a human on site even if said human is simply trying to escape such as when Neville rescues Sam when she pursued the deer into the Darkseeker-occupied building? Ironically this seems to make the theatrical FocusGroupEnding more consistent with the rest of the movie.

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* Not to say I don’t like the alternate ending but it seems to be that there is a conflict between the alternate ending and the rest of the movie. Robert tells Anna that the virus originally killed 90% of the human population (5.4 billion) leaving less than 1% that were immune (12 million) and the rest (588 million) turned into the Darkseekers and then slaughtered most of the immune, but doesn’t this contradict with how in the alternate ending the Darkseekers were actually intelligent and had a capacity for empathy because the leader simply wanted his mate back and left peacefully once Neville returned her, thus leading to Neville’s realization that to them ''he'' is the monster, but how can that be if they killed most of the immune and will pursue and attack a human on site sight even if said human is simply trying to escape such as when Neville rescues Sam when she pursued the deer into the Darkseeker-occupied building? Ironically this seems to make the theatrical FocusGroupEnding more consistent with the rest of the movie.
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* Not to say I don’t like the alternate ending but it seems to be that there is a conflict between the alternate ending and the rest of the movie. Robert tells Anna that the virus originally killed 90% of the human population (5.4 billion) leaving less than 1% that were immune (12 million) and the rest (588 million) turned into the Darkseekers and then slaughtered most of the immune, but doesn’t this contradict with how in the alternate ending the Darkseekers were actually intelligent and had a capacity for empathy because the leader simply wanted his mate back and left peacefully once Neville returned her, thus leading to Neville’s realization that to them ''he'' is the monster, but how can that be if they killed most of the immune and will pursue and attack a human on site even if said human is simply trying to escape such as when Neville follows Sam when she pursued the deer into the building? Ironically this seems to make the theatrical FocusGroupEnding more consistent with the rest of the movie.

to:

* Not to say I don’t like the alternate ending but it seems to be that there is a conflict between the alternate ending and the rest of the movie. Robert tells Anna that the virus originally killed 90% of the human population (5.4 billion) leaving less than 1% that were immune (12 million) and the rest (588 million) turned into the Darkseekers and then slaughtered most of the immune, but doesn’t this contradict with how in the alternate ending the Darkseekers were actually intelligent and had a capacity for empathy because the leader simply wanted his mate back and left peacefully once Neville returned her, thus leading to Neville’s realization that to them ''he'' is the monster, but how can that be if they killed most of the immune and will pursue and attack a human on site even if said human is simply trying to escape such as when Neville follows rescues Sam when she pursued the deer into the Darkseeker-occupied building? Ironically this seems to make the theatrical FocusGroupEnding more consistent with the rest of the movie.
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None


* Not to say I don’t like the alternate ending but it seems to be that there is conflict between the message of the alternate ending and the rest of the movie. Robert tells Anna that the virus originally killed 90% of the human population (5.4 billion) leaving less than 1% that were immune (12 million) and the rest (588 million) turned into the Darkseekers and then slaughtered most of the immune, but doesn’t this contradict the message that the Darkseekers were actually intelligent and had a capacity for empathy because the leader simply wanted his mate back and left peacefully once Neville returned her, thus leading to Neville’s realization that to them ''he'' is the monster, but how can that be if they killed most of the immune and will just attack and pursue any human on site even if said human is not attacking them and is trying to escape such as when Neville follows Sam when she pursued the deer into the building? Ironically this seems to make the theatrical FocusGroupEnding more consistent with the rest of the movie.

to:

* Not to say I don’t like the alternate ending but it seems to be that there is a conflict between the message of the alternate ending and the rest of the movie. Robert tells Anna that the virus originally killed 90% of the human population (5.4 billion) leaving less than 1% that were immune (12 million) and the rest (588 million) turned into the Darkseekers and then slaughtered most of the immune, but doesn’t this contradict with how in the message that alternate ending the Darkseekers were actually intelligent and had a capacity for empathy because the leader simply wanted his mate back and left peacefully once Neville returned her, thus leading to Neville’s realization that to them ''he'' is the monster, but how can that be if they killed most of the immune and will just pursue and attack and pursue any a human on site even if said human is not attacking them and is simply trying to escape such as when Neville follows Sam when she pursued the deer into the building? Ironically this seems to make the theatrical FocusGroupEnding more consistent with the rest of the movie.
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* Not to say I don’t like the alternate ending but it seems to be that there is conflict between the message of the alternate ending and the rest of the movie. Robert tells Anna that the virus originally killed 90% of the human population (5.4 billion) leaving less than 1% that were immune (12 million) and the rest (588 million) turned into the Darkseekers and then slaughtered most of the immune, but doesn’t this contradict the message that the Darkseekers were actually intelligent and had a capacity for empathy because the leader simply wanted his mate back and left peacefully once Neville returned her, thus leading to Neville’s realization that to them ''he'' is the monster, but how can that be if they killed most of the immune and will just attack and pursue any human on site even if said human is not attacking them and is trying to escape such as when Neville follows Sam when she pursued the deer into the building? Ironically this seems to make the theatrical FocusGroupEnding more consistent with the rest of the movie.
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** In addition to the other great points made here, it's worth pointing out that they ''did'' test KV. The very first scene of the film is an interview with Krippen who says that they had a test cadre of 10,009 patients with 10,009 successes. Since even the most jaded clinical researcher would notice if a test patient was losing their hair, getting a constant sunburn, and trying to snack on the floor nurse, it's a reasonable conclusion that in the beginning KV actually worked perfectly as intended. The problem is that viruses replicate fast and aren't perfectly genetically stable. So over the course of treatment, one replication of the virus in one patient went wrong and created the virus that destroyed humanity; since it was able to replicate and spread better, it became the dominant strain, then spread. To use Krippen's own analogy, the police car was stolen by a bad man. Since clinical trial patients are allowed to go home and live their normal lives, by the time anyone realized something was wrong the virus had already spread beyond containment.
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*** Very valid points, but his "this is personal" attitude extended to before his family died. During the drive to the pier, when his wife demands to know why he isn't coming, he very emphatically states "This is ''my site.''" That's a very strong possessive statement and indicates that this is already a deeply personal battle for him.
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** The alternate (non-theatrical) ending also shows that after Neville disconnects the IV drip her symptoms return within a handful of seconds. It'd be reasonable to assume that she wasn't cured, merely responding positively to treatment, and definitely not someone who's safe to bring along.

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