History DespairEventHorizon / AnimeAndManga

* GaReiZero shows Yomi [[TraumaCongaLine descending into one of these]], finally crossing it when she believes Kagura, the one dearest to her and the last person to believe in her, has abandoned her. Leads to a TearJerker moment as all she can do is type out "I'm sorry Kagura" before accepting the Banestone/Sesshouseki in her despair.

* Yomi from ''GaReiZero''. [[spoiler: Yomi's adoptive father his killed by her Seishouseki-mind-controlled adoptive [[TheRival cousin]], the cousin takes what was supposed to be her place as the family head and her inheritance, then lures her to a fight. When the cousin admits killing Yomi's father, she goes [[BerserkButton berserk]] and kills her. Then [[ManipulativeBastard Mitogawa]] attacks Yomi, rendering her quadriplegic and mute, and she is accused of murdering her cousin. Her fiancee Noriyuki is too busy trying to prove her innocence to visit her in the hospital, his father breaks off their PerfectlyArrangedMarriage because of her physical condition, and her best friend Kagura abandons her after she admits to killing her cousin. Then Mitogawa gives her the same Seishouseki, which heals her but its mind-control powers provide the extra push to send her JumpingOffTheSlipperySlope and killing her former friends.]] Her Despair Event Horizon is such a {{Tearjerker}} that even after crossing the MoralEventHorizon she is still a sympathetic WoobieDestroyerOfWorlds.

* This happens a ''lot'' in ''VisualNovel/HigurashiNoNakuKoroNi'', to a number of different characters. In fact, it's the reason for most of the murderous rampages on the show, if not all.

* In ''RanmaOneHalf'', Ryoga has developed a [[KiAttacks ki attack]] that grows more powerful as he gets more depressed. In a battle where he's using this technique to solidly pound Ranma into the ground, Akane tries to cut through Ryouga's depression with a cheerful "Don't be sad! I really like you, Ryoga!... You're such a great ''friend!''" Since Ryoga is desperately in love with her and is horrified that she only considers him a friend, this unwittingly pushes him over the Despair Event Horizon and [[StopHelpingMe makes his attacks]] ''[[StopHelpingMe even stronger.]]''

* Jose in ''GunslingerGirl'' crosses it when he loses an eye in a botched attempt to kill the terrorist who killed Enrica, and cyborg girl Henrietta is reset to factory settings, destroying her personality so she'll never be able to take Enrica's place. By the nuclear power plant strike, Jose was so far beyond the Despair Event Horizon that [[spoiler:after getting fragged, he has Henrietta finish the job and, as she does so, [[TakingYouWithMe shoots her in the eye, killing her]].]]
* Most of the main plot of ''{{Trigun}}'' that made it into the anime (the manga had all this backstory stuff and Knives going OneWingedAngel and staying that way for over a year while he slowly killed off the human race) was a BreakTheCutie-slash-Break the Stoic plot aimed at pushing Vash over this, probably in hopes of inducing FaceHeelTurn, but possibly just to punish him for being a disloyal brother. It works insofar as he is pushed past his (admittedly impressive) limits on a couple of occasions, which variously result in a [[TenMinuteRetirement two year retirement]] and [[HeroicBSOD brief catatonia]].

* Many of the past victims and {{Sympathetic Murderer}}s in DetectiveConan are people who, for one or another reason, have crossed the DEH and either died or became killers as an effect. The case involving [[spoiler: the StarCrossedLovers Hideomi and Miyuki]] is a very blatant example: the first [[spoiler: had lived in the fence after a DeadlyPrank caused him to be scarred and killed Miyuki's parents, but crossed it when Miyuki fell in love with him ''despite his crime'', which caused him to commit suicide]]; the second went past the DEH fence [[spoiler: when she found Hideomi's corpse, pushing ''her'' to murder the other person involved in the DeadlyPrank by using said person's own plans against him, and then to try commiting suicide so she and Hideomi could be TogetherInDeath. (She's [[InterruptedSuicide stopped]] by Conan, and is soon screaming and crying about how badly she wants to die, until Hideomi's father gently talks her out of it.)]]

* [[spoiler: Tsubaki Kasugano aka the 6th]] in ''MiraiNikki'' crosses this in her backstory, after [[spoiler: she loses the TragicKeepsake that kept her somewhat sane after being used as a SexSlave by a ReligionOfEvil.]] By the time we meet her, she's a full-blown WoobieDestroyerOfWorlds.

* From ''Manga/NanatsuNoTaizai'', this is what drove Helbram into becoming an AxCrazy human massacring FauxAffablyEvil villain. [[spoiler: After he and a few of his fairy friends were captured by greedy humans wanting to use their wings for medicine, and after witnessing firsthand his friends get their wings ripped off, he loses all the respect and fascination he once had for humanity. So much so that he can longer stop himself from killing humans regardless of his own desires.]]

* It happens to Yuma in ''Anime/YuGiOhZEXAL'' during his duel with III, but is subverted due to the fact that III uses a curse to steal Yuma's self-confidence, literally. [[spoiler: Yuma is able to recover after his father appears to him in a vision, reminding him how he got the self-confidence to begin with.]]

* ''DigimonTamers'': Jeri goes over this after [[spoiler:her partner Leomon is killed ''and eaten'' right in front of her]]. Her despair was so much that the [[BigBad D-Reaper]] decided it liked the taste of her sorrow and [[MoralEventHorizon possessed her so it could]] ''[[MoralEventHorizon continue]]'' [[MoralEventHorizon driving her over this]] by [[MindRape emotionally and mentally torturing her]]. It succeeds so well that she [[spoiler:[[InterruptedSuicide tries to commit]] ''[[InterruptedSuicide suicide]]'' to escape]].

* Shinji crosses this line in ''Anime/NeonGenesisEvangelion'' when he is [[spoiler:[[ShootTheDog forced to kill Kaworu]]]], although that '''isn't'' actually his lowest point. That comes after [[spoiler:he [[ADateWithRosiePalms masturbates]] at [[DudeShesLikeInAComa the comatose Asuka's bedside]]]], at which point he realizes that he has truly hit rock bottom.
** By midway through End of Evangelion, nothing is left but a shrieking mess.

** For Shinji's [[RebuildOfEvangelion Rebuild]] incarnation, it's either finding out that he [[spoiler: never saved Rei (...which also shattered his feeble attempts to cope with having [[NiceJobBreakingItHero inadvertedly annihilated the biosphere]])]] or [[spoiler: [[MoreHeroThanThou Kaworu's]] [[YourHeadASplode death]] [[HeroicSacrifice yet again]], which, this time, was a direct result of Shinji [[GoneHorriblyWrong making a poor decision]] in a desperate situation and rendered completely [[SenselessSacrifice senseless]] by Shinji's ''mere presence'' inside EVA 13.]] After that, he just curls into a ball and waits for death, not even reacting to Asuka kicking him right afterwards. [[CosmicPlaything And yes, this is the very next thing that happens to him.]]

** Gluttony after [[spoiler:Lust dies]].

** Naruto nearly crossed it when it seemed Hinata was killed by Pein, right before his very eyes. Luckily, his [[spoiler:dad]] brought him back.
** Nagato himself crossed it when [[HeroicSacrifice Yahiko killed himself in order to save Konan]]. This can be considered the moment when Pein was born.

* In ''MagicKnightRayearth'', [[spoiler: Princess Emeraude]] plowed through this when [[spoiler: her beloved Zagato was killed by the Knights, believing him to be the BigBad.]] She already was unstable after [[spoiler: having to send her brother Ferio away after giving him LaserGuidedAmnesia, then keeping her love for Zagato bottled up, seeing that since she couldn't devote herself 100% to Cephiro, her [[FisherKing Pillar work]] wasn't effective as it should be, ''and'' being kidnapped by a desperate Zagato who doesn't want the Knights to release her from Pillar-dom through death]]... and once [[spoiler: Zagato kicked it in battle]], the [[BreakTheCutie poor broken person]] reacted by [[spoiler: unleashing her powers on the Knights and trying to kill them, calling them out on his death. The girls have to give her an ICannotSelfTerminate, and the DownerEnding of the first season kicks in.]]

* ''JyuOhSei'' brings us Third/[[spoiler:Heiser]], who, after learning that [[spoiler: Earth, which he had dreamed of visiting for his entire life, was destroyed]]. He collapses in despair, spends a good few minutes staring blankly at nothing, and eventually [[spoiler: shoots himself in the head. Admittedly, his suicide was more to save Thor than a result of his Despair Event Horizon, but it still counts]].

** The final arc all but confirms Ryuuken Ishida's hatred of Quincies is because he's a StepfordSnarker who crossed into this trope years ago. [[spoiler: Twenty years ago, Ryuuken's ability to protect the future of the quincies is destroyed. His GreyRainOfDepression culminates in an HeroicBSOD that only just escapes this trope thanks to a YouAreNotAlone speech by his future wife, [[NinjaMaid Kanae Katagiri]]. A few years later, the [[TheEmperor Quincy King]] inflicts a CruelAndUnusualDeath on Kanae, kicking Ryuuken into this trope for good.]]

** The final arc all but confirms Ryuuken Ishida's hatred of Quincies is because he's a StepfordSnarker who crossed into this trope years ago. [[spoiler: Twenty years ago, Ryuuken's ability to protect the future of the quincies is destroyed. His GreyRainOfDepression culminates in an HeroicBSOD that only just escapes this trope thanks to a YouAreNotAlone speech by his future wife, [[NinjaMaid Kanae Katagiri]]. A few years later, the Quincy King inflicts a CruelAndUnusualDeath on Kanae, kicking Ryuuken into this trope for good.]]

** The final arc all but confirms Ryuuken Ishida's hatred of Quincies is because he's a StepfordSnarker who crossed into this trope years ago. [[spoiler: Twenty years ago, Ryuuken's ability to protect the future of the quincies is destroyed. His GreyRainOfDepression culminates in an HeroicBSOD that only just escapes this trope thanks to a YouAreNotAlone speech by his future wife, [[NinjaMaid Katagiri]]. A few years later, Katagiri suffers a CruelAndUnusualDeath and, with the Quincy responsible still at large, Ryuuken's been an example of this trope ever since.]]

** [[spoiler:Madara]] crossed it (by his own admission) when he found out the AwfulTruth about the history of the ninja world and [[GoMadFromTheRevelation came to realize how hopeless the idea of achieving true peace really was]]. He subsequently comes up with an AssimilationPlot as he feels that it's the only hope for humanity.

** Kiba suffers [[TearJerker a heartbreaking one]] as well. [[spoiler: After fighting an epic battle with the BigBad for Cheza's safety, [[InterspeciesRomance his humanoid flower/girlfriend,]] and reason for living, ''disintegrates into millions of seeds in his own hands.'' He for the first time ever completely gives up and dies shortly after. [[LastOfHisKind He's also the last thing on earth to die.]]]]

** [[spoiler:Madara]] crossed it (by his own admission) when he found out the AwfulTruth about the history of the ninja world and [[GoMadFromTheRevelation came to realize how hopeless the idea of achieving true peace really was]]. He subsequently comes up with an AssimilationPlot as he feels that it's the only hope for humanity.]]

* In ''Manga/AttackOnTitan'', Mikasa suffers one when [[spoiler:she thinks Eren died]]. [[spoiler:Reiner]] appears to have gone over it after [[spoiler:revealing his true identity. He clings to the idea of completing his mission in order to function but is resigned to dying as a mass murderer]].

** Kiba suffers [[TearJerker a heartbreaking one]] as well. [[spoiler: After fighting an epic battle with the BigBad for Cheza's safety, [[InterspeciesRomance his humanoid flower/girlfriend,]] and reason for living, ''disintegrates into millions of seeds in his own hands.'' [[HeroicBSOD He never gets over it,]] and dies shortly after. [[LastOfHisKind He's also the last thing on earth to die.]]]]

* In the ''[[MahouSenseiNegima Negima!]]'' (first) anime, Negi himself crosses the horizon after [[spoiler: Asuna's death on her [=14th=] birthday, when the DealWithTheDevil she made as a kid takes effect.]] He splinters so badly that watching it almost becomes the DEH for a few of his students.

** Second is Mikoto[='=]s, which is much, much deeper. [[spoiler:She's trying to stop the Level 6 Shift experiments, and after pushing herself to her limits and still failing, she comes to the conclusion that the only way to stop the experiments is ''her'' suicide.]]

* In ''HaibaneRenmei'', this is arguably[[spoiler: what allows Rakka and Reki to no longer be bound by sin.]]

* Griffith of ''{{Berserk}}'', broken in body and mind after a year's worth of torture, loses all hope of becoming captain of the Band of the Hawks again when it's discovered that he will never recover from his injuries. Then, just after he resigns himself to living a peaceful life with Casca, he discovers that she's moved on and is now in a relationship with Guts. Griffith loses it completely. This drives him to activate his Crimson Behelit, summon the Godhand, and cross the MoralEventHorizon.

* It happens to Yuma in ''Anime/YuGiOhZexal'' during his duel with III, but is subverted due to the fact that III uses a curse to steal Yuma's self-confidence, literally. [[spoiler: Yuma is able to recover after his father appears to him in a vision, reminding him how he got the self-confidence to begin with.]]

** [[spoiler:Homura approaches this during her fight with Walpurgis Night, realizing she's about to lose again and has to wrestle with the choice of rewinding time again, and risk corrupting Madoka's future more, or give in. Her Soul Gem starts becoming increasingly corrupted during this time.]]

** Several characters were actually very close to this, as well. Nami, Robin, Zoro, [[spoiler: Hancock]], etc.