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*** Historically the Boltons, another noble Northern House, were the enemies of House Stark, even murdering some of the Stark Kings. The hostilities seemed to have centuries ago, [[spoiler:however the Boltons end up betraying the Starks and Lord Bolton murders King Robb Stark.]]
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*** Historically the Boltons, another noble powerful Northern House, were the enemies of House Stark, even murdering killing some of the Stark Kings. The hostilities seemed to ended have centuries ago, [[spoiler:however the Boltons end up betraying the Starks and Lord Bolton murders King Robb Stark.]]
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** [[BigGood Manwe]], King of the Vala, and [[BigBad Melkor]] Arda's GodOfEvil, later known as Morgoth Bauglir, are this. However Tulkas could also be considered this for Morgoth as he defeats them personally twice in combat, and them entering Arda caused Morgoth to flee, giving peace for a time. Morgoth could be considered this for many of the heroes of the First Age, such as Beren and Hurin.
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** [[BigGood Manwe]], King of the Vala, and [[BigBad Melkor]] Arda's GodOfEvil, later known as Morgoth Bauglir, are this. However Tulkas could also be considered this for Morgoth as he defeats them personally twice in combat, and them him entering Arda caused Morgoth to flee, giving peace for a time. Morgoth could be considered this for many of the heroes of the First Age, such as Beren and Hurin.
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** Glaurung, Father of Dragons, serves as this for Turin and his sister Nienor in "Literature/TheChildrenOfHurin". Bear in mind that Morgoth had cursed their father Hurin and his family so could be considered the enemy of their family, [[spoiler:his actions eventually wiping them out.]] However Glaurung is the one who causes the most trouble directly for them [[spoiler:driving them to [[DrivenToSuicide suicide]].]]
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** Glaurung, Father of Dragons, serves as this for Turin and his sister Nienor in "Literature/TheChildrenOfHurin". Bear in mind that Morgoth had cursed their father Hurin and his family so could be considered the enemy of their family, [[spoiler:his actions eventually wiping them out.]] However Glaurung is the one who causes the most trouble directly for them [[spoiler:driving them them, even though Turin kills him [[spoiler:his actions drive Turin and his sister to [[DrivenToSuicide suicide]].]]
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*** Historically the Boltons, another noble Northern House, were the enemies of House Stark, even murdering some of the Stark Kings. The hostilities seemed to have centuries ago, [[spoiler:however the Boltons end up betraying the Starks and Lord Bolton murders King Robb Stark.]]
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* ''Literature/TheSagaOfArrowOdd'': Ogmund Eythjofslayer and Odd are locked in a deadly feud that lasts for most of their lives and has been triggered by Odd's depredation of Bjarmaland, Odd's very first viking cruise and the same voyage that made him rich and famous in the first place. Despite being deadly enemies, they also have much in common--such as being nigh-immortals who dedicate their lives to the quest for glory by battle and conquest.
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*President Snow, Cato, and Clove to Katniss Everdeen and Peeta Mellark in ''Literature/TheHungerGames''.
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* ''Literature/TheBelgariad'': The Prophecy and Dark Prophecy are cosmic archenemies. On the human level we have Belgarah, Disciple of Aldur, and Ctuchik, Disciple of Torak, who have loathed one another for eons.
* ''Literature/TheElenium'': Sparhawk and his one-time friend Martel, who also act as one another's {{Evil Counterpart}}s.
* ''Literature/TheElenium'': Sparhawk and his one-time friend Martel, who also act as one another's {{Evil Counterpart}}s.
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*Anton Chiguhr to Llewelyn Moss and Ed Tom Bell in ''Literature/NoCountryForOldMen''.
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* Messala to Judah Ben-Hur in ''Literature/Ben-Hur''.
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* Messala to Judah Ben-Hur in ''Literature/Ben-Hur''.''Literature/BenHur''.
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**Will Graham also has Francis Dolarhyde, and Clarice Starling also has Buffalo Bill and Mason Verger.
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* Messala to Judah Ben-Hur in ''Literature/Ben-Hur''.
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* Pennywise to the Losers' Club in ''Literature/It''.
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* Pennywise to the Losers' Club in ''Literature/It''.''Literature/{{IT}}''.
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*Pennywise to the Losers' Club in ''Literature/It''.
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* Bob Ewell to Atticus Finch and Tom Robinson in ''Literature/{{ToKillAMockingbird}}''.
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* Bob Ewell to Atticus Finch and Tom Robinson in ''Literature/{{ToKillAMockingbird}}''.''Literature/ToKillAMockingbird''.
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*Bob Ewell to Atticus Finch and Tom Robinson in ''Literature/{{ToKillAMockingbird}}''.
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*Smaug to Thorin Oakenshield and his company.
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* Nurse Ratched is the archenemy of Randle McMurphy in ''Literature/OneFlewOverTheCuckoosNest''.
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* Nurse Ratched is the archenemy of Randle McMurphy [=McMurphy=] in ''Literature/OneFlewOverTheCuckoosNest''.
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* Annie Wilkes to Paul Sheldon in ''Literature/Misery''.
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* Annie Wilkes to Paul Sheldon in ''Literature/Misery''.''Literature/{{Misery}}''.
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* Nurse Ratched to Randle McMurphy in ''Literature/OneFlewOverTheCuckoosNest''.
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* Nurse Ratched to is the archenemy of Randle McMurphy in ''Literature/OneFlewOverTheCuckoosNest''.
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* Nurse Ratched to Randle McMurphy in ''Literature/OneFlewOverTheCuckoo'sNest''.
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* Nurse Ratched to Randle McMurphy in ''Literature/OneFlewOverTheCuckoo'sNest''.''Literature/OneFlewOverTheCuckoosNest''.
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** Glaurung, Father of Dragons, serves as this for Turin and his sister Nienor in "Literature/TheChildrenOfHurin". Bear in mind that Morgoth had cursed their father Hurin and his family so could be considered the enemy of their family, [[spoiler:his actions eventually wiping them out.]] However Glaurung is the one who causes the most trouble directly for them [[spoiler:driving them to [[DrivenToSuicide suicide]].]]
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** Glaurung, Father of Dragons, serves as this for Turin and his sister Nienor in "Literature/TheChildrenOfHurin". Bear in mind that Morgoth had cursed their father Hurin and his family so could be considered the enemy of their family, [[spoiler:his actions eventually wiping them out.]] However Glaurung is the one who causes the most trouble directly for them [[spoiler:driving them to [[DrivenToSuicide suicide]].]]]]
*Sauron to the Fellowship of the Ring in ''Literature/LordOfTheRings''. Sauron also had Galadriel, Gil-galad, Elrond, Elendil, Isildur, and Círdan in particular.
**Saruman to Gandalf.
**Gollum to Bilbo Baggins, Frodo Baggins, and Samwise Gamgee.
*Doctor Hannibal Lector to Will Graham and Clarice Starling.
*Jack Torrance eventually becomes this to Wendy and Danny Torrance in ''Literature/TheShining''.
*Nurse Ratched to Randle McMurphy in ''Literature/OneFlewOverTheCuckoo'sNest''.
*Annie Wilkes to Paul Sheldon in ''Literature/Misery''.
*Sauron to the Fellowship of the Ring in ''Literature/LordOfTheRings''. Sauron also had Galadriel, Gil-galad, Elrond, Elendil, Isildur, and Círdan in particular.
**Saruman to Gandalf.
**Gollum to Bilbo Baggins, Frodo Baggins, and Samwise Gamgee.
*Doctor Hannibal Lector to Will Graham and Clarice Starling.
*Jack Torrance eventually becomes this to Wendy and Danny Torrance in ''Literature/TheShining''.
*Nurse Ratched to Randle McMurphy in ''Literature/OneFlewOverTheCuckoo'sNest''.
*Annie Wilkes to Paul Sheldon in ''Literature/Misery''.
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* This shows up a bit in Franchise/TolkiensLegendarium.
** [[BigGood Manwe]], King of the Vala, and [[BigBad Melkor]] Arda's GodOfEvil, later known as Morgoth Bauglir, are this. However Tulkas could also be considered this for Morgoth as he defeats them personally twice in combat, and them entering Arda caused Morgoth to flee, giving peace for a time. Morgoth could be considered this for many of the heroes of the First Age, such as Beren and Hurin.
** Huan, the greatest wolfhound in Middle-Earth, and Carcharoth, the greatest wolf to have ever lived, who was created by Morgoth because of a prophecy that only such a wolf could kill Huan. They end up performing a MutualKill.
** Glaurung, Father of Dragons, serves as this for Turin and his sister Nienor in "Literature/TheChildrenOfHurin". Bear in mind that Morgoth had cursed their father Hurin and his family so could be considered the enemy of their family, [[spoiler:his actions eventually wiping them out.]] However Glaurung is the one who causes the most trouble directly for them [[spoiler:driving them to [[DrivenToSuicide suicide]].]]
** [[BigGood Manwe]], King of the Vala, and [[BigBad Melkor]] Arda's GodOfEvil, later known as Morgoth Bauglir, are this. However Tulkas could also be considered this for Morgoth as he defeats them personally twice in combat, and them entering Arda caused Morgoth to flee, giving peace for a time. Morgoth could be considered this for many of the heroes of the First Age, such as Beren and Hurin.
** Huan, the greatest wolfhound in Middle-Earth, and Carcharoth, the greatest wolf to have ever lived, who was created by Morgoth because of a prophecy that only such a wolf could kill Huan. They end up performing a MutualKill.
** Glaurung, Father of Dragons, serves as this for Turin and his sister Nienor in "Literature/TheChildrenOfHurin". Bear in mind that Morgoth had cursed their father Hurin and his family so could be considered the enemy of their family, [[spoiler:his actions eventually wiping them out.]] However Glaurung is the one who causes the most trouble directly for them [[spoiler:driving them to [[DrivenToSuicide suicide]].]]
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* [[BigBad Shere Khan]] the tiger to Mowgli in [[TheJungleBook The Jungle Book]] and it's adaptations.
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* Theseus Spencer to Oberon Navarro in ''{{Literature/Alterien}}''.
* Captain Ciaran Devlyn to Caspian Knoll in ''Literature/AstralDawn''.
* Captain Ciaran Devlyn to Caspian Knoll in ''Literature/AstralDawn''.
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* Theseus Spencer to Oberon Navarro in ''{{Literature/Alterien}}''.
* Captain Ciaran Devlyn to Caspian Knoll in ''Literature/AstralDawn''.
* Captain Ciaran Devlyn to Caspian Knoll in ''Literature/AstralDawn''.
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* Captain Ciaran Devlyn to Caspian Knoll in ''{{Literature/Astral Dawn}}''.
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* Captain Ciaran Devlyn to Caspian Knoll in ''{{Literature/Astral Dawn}}''.''Literature/AstralDawn''.
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* Theseus Spencer to Oberon Navarro in {{Literature/Alterien}}.
* Captain Ciaran Devlyn to Caspian Knoll in Astral Dawn.
* Captain Ciaran Devlyn to Caspian Knoll in Astral Dawn.
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* Theseus Spencer to Oberon Navarro in {{Literature/Alterien}}.
''{{Literature/Alterien}}''.
* Captain Ciaran Devlyn to Caspian Knoll inAstral Dawn.''{{Literature/Astral Dawn}}''.
* Captain Ciaran Devlyn to Caspian Knoll in
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* The balor Errtu is the self-proclaimed archenemy of [[Literature/TheLegendOfDrizzt Drizzt]]. Errtu claims that no one else [[ThePowerOfHate hates]] Drizzt as much as he does. Errtu is glad that Drizzt is a Dark Elf, a being whose projected lifespan can be measured in centuries, since this means there's a good chance Drizzt will still be alive when Errtu is eventually allowed to leave the Abyss. Every time Errtu finds a way out of the Abyss he makes a beeline for Drizzt. During one of his stays in the Abyss, Errtu took great pleasure in torturing the soul of one of Drizzt's friends. While Drizzt has other foes like the assassin Artemis Entreri and the orc king Obould Many-Arrows [[spoiler:who both eventually make peace with Drizzt]], Errtu is far more evil than either of those two and is also the only one who could theoretically hound Drizzt for the rest of his life.
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* The balor Errtu is the self-proclaimed archenemy of [[Literature/TheLegendOfDrizzt Drizzt]]. Errtu claims that no one else [[ThePowerOfHate hates]] Drizzt as much as he does. Errtu is glad that Drizzt is a Dark Elf, a being whose projected lifespan can be measured in centuries, since this means there's a good chance Drizzt will still be alive when Errtu is eventually allowed to leave the Abyss. Every time Errtu finds a way out of the Abyss he makes a beeline for Drizzt. During one of his stays in the Abyss, Errtu took great pleasure in torturing the soul of one of Drizzt's friends. While Drizzt has other foes like the assassin Artemis Entreri and the orc king Obould Many-Arrows [[spoiler:who both eventually make peace with Drizzt]], Errtu is far more evil than either of those two and is also the only one who could theoretically hound Drizzt for the rest of his life.life.
* Theseus Spencer to Oberon Navarro in {{Literature/Alterien}}.
* Captain Ciaran Devlyn to Caspian Knoll in Astral Dawn.
* Theseus Spencer to Oberon Navarro in {{Literature/Alterien}}.
* Captain Ciaran Devlyn to Caspian Knoll in Astral Dawn.
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* Franny Roote in Reginald Hill's DalzielAndPascoe novels: although Hill dispatches Roote to jail in the series' second novel, ''An Advancement of Learning'', he resurrects him as Pascoe's obsession in ''Arms and the Women'', ''Dialogues of the Dead'', and ''Death's Jest-Book'', then finally elevates him to true Arch Enemy status in ''A Cure for All Diseases''.
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* Franny Roote in Reginald Hill's DalzielAndPascoe ''Literature/DalzielAndPascoe'' novels: although Hill dispatches Roote to jail in the series' second novel, ''An Advancement of Learning'', he resurrects him as Pascoe's obsession in ''Arms and the Women'', ''Dialogues of the Dead'', and ''Death's Jest-Book'', then finally elevates him to true Arch Enemy status in ''A Cure for All Diseases''.
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* The balor Errtu is the self-proclaimed archenemy of [[Literature/TheLegendOfDrizzt Drizzt]]. Errtu claims that no one else [[ThePowerOfHate hates]] Drizzt as much as he does. Errtu is glad that Drizzt is a Dark Elf, a being whose projected lifespan can be measured in centuries, since this means there's a good chance Drizzt will still be alive when Errtu is eventually allowed to leave the Abyss. Every time Errtu finds a way out of the Abyss he makes a beeline for Drizzt. During one of his stays in the Abyss, Errtu took great pleasure in torturing the soul of one of Drizzt's friends. While Drizzt has other foes like the assassin Artemis Entreri and the orc king Obould Many-Arrows, Errtu is far more evil than either of those two and is also the only one who could theoretically hound Drizzt for the rest of his life.
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* The balor Errtu is the self-proclaimed archenemy of [[Literature/TheLegendOfDrizzt Drizzt]]. Errtu claims that no one else [[ThePowerOfHate hates]] Drizzt as much as he does. Errtu is glad that Drizzt is a Dark Elf, a being whose projected lifespan can be measured in centuries, since this means there's a good chance Drizzt will still be alive when Errtu is eventually allowed to leave the Abyss. Every time Errtu finds a way out of the Abyss he makes a beeline for Drizzt. During one of his stays in the Abyss, Errtu took great pleasure in torturing the soul of one of Drizzt's friends. While Drizzt has other foes like the assassin Artemis Entreri and the orc king Obould Many-Arrows, Many-Arrows [[spoiler:who both eventually make peace with Drizzt]], Errtu is far more evil than either of those two and is also the only one who could theoretically hound Drizzt for the rest of his life.
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* The Nome King is the Arch Enemy of Dorothy Gale and Ozma of Oz in the ''Literature/LandOfOz'' series.
* Professor Moriarty is Literature/SherlockHolmes' Arch Enemy and WorthyOpponent.
** Almost by default, since he only really appears in two stories written by Sir Arthur Conan Doyle.
* In ''Franchise/TheDarkTower'', Walter is Roland's Arch Enemy, but not the BigBad.
* Ernst Stavro Blofeld becomes Literature/JamesBond's Arch Enemy over the course of three books, until Bond himself comes to think of it as a blood feud and refuses to get [=MI6=] involved.
* ''Literature/HarryPotter'':
** Voldemort to Harry. Also jerkass Draco Malfoy and Severus Snape, at least until [[spoiler:Snape's death.]]
** Rita Skeeter to Hermione Granger.
** Bellatrix Lestrange to Neville Longbottom, Hermione Granger and the Weasley family.
** The Malfoy family to the Weasley family.
** Voldemort (and previously, Gellert Grindelwald) to Dumbledore.
* Morjin to Valashu in the ''EaCycle''.
* {{Dracula}} meets his match after 400 years in the person of [[TheHunter Abraham Van Helsing]].
* ''SoonIWillBeInvincible'': After defeating Doctor Impossible and discovering her ties to him, Fatale considers this might make him her Arch Enemy, but is it worth it?
-->I suppose I ought to vow to oppose him forever; make a nemesis issue of it. But it's a little beside the point. ... with [[spoiler: [=CoreFire=]]] back, he's already got a nemesis. I'd have to be a co-nemesis. ... I'm not 100 percent sure what I'm supposed to angry about, if we come down to it.
* Hakeswill in {{Sharpe}} seems to dedicate himself expressly to making Sharpe's life miserable - he has him flogged in pre-{{canon}}, he has Harper flogged after figuring out how close he and Sharpe are, he attempts to rape and [[spoiler: eventually murders]] Sharpe's wife... Sharpe tries and fails to kill him in repeated inventive ways before [[spoiler:he finally gets to give him the coup de grace at his execution]].
** Once Hakeswill had been written out of the novels, this role was arguably taken over by Major Ducos, a French spymaster who is constantly coming up with schemes to hamstring, if not outright stop, the British war effort, as well as to humiliate, discredit and kill Sharpe in the process.
* Lex Luthor (or the Guy who took the name-Like he cared about a copyright infringment suit) thought he was in ''Literature/TalesOfAnMazingGirl''. He was more of a minor threat.
** The Duke of Wellington and NapoleonBonaparte, whom some like to see as historical archenemies, even though they probably did not see themselves that way, show up in the series.
* John Devil, from the eponymous novel by Paul Feval is the Arch Enemy of Inspector Gregory Temple, as well as being one of the earliest super-villains, anticipating the aforementioned Moriarty with about 30 years.
* Carl Peterson was the Arch Enemy of BulldogDrummond, until he was killed in the fourth novel. Afterwards, Carl's mistress, Irma took over his role.
* Ballmeyer, [[spoiler:aka Detective Frederic Larsan]] is the Arch Enemy of Joseph Rouletabille as well as the latter's [[spoiler:biological father]].
* Franny Roote in Reginald Hill's DalzielAndPascoe novels: although Hill dispatches Roote to jail in the series' second novel, ''An Advancement of Learning'', he resurrects him as Pascoe's obsession in ''Arms and the Women'', ''Dialogues of the Dead'', and ''Death's Jest-Book'', then finally elevates him to true Arch Enemy status in ''A Cure for All Diseases''.
* Visser Three to the Literature/{{Animorphs}}.
** He was also Elfangor's Arch Enemy, to an even more [[ItsPersonal personal degree]]. On a lesser scale, [[TortureTechnician Taylor]] is this to [[TheWoobie Tobias]], and [[SixthRangerTraitor David]] sees himself as [[TheBigGuy Rachel's]]. And then there's cosmic archenemies, [[BiggerBad Crayak]] and [[BigGood The Ellimist]]. One could also make the case for [[EvilMatriarch Visser One]] being [[TheLancer Marco]]'s Arch Enemy.
* Chauvelin for the eponymous hero of ''Literature/TheScarletPimpernel'', with generous traces of InspectorJavert and FoeYay.
* In the BackStory of Creator/RobertEHoward's ConanTheBarbarian story "The Phoenix on the Sword", Set was this to Epemitreus. Which is part of why he helps Conan against Thoth-amon, one of Set's votaries.
* The Deaf Man in the ''Literature/EightySeventhPrecinct'' series by Creator/EdMcBain.
* CompanionsQuartet has Kullervo for the main character Connie
* In the ''Literature/WarriorCats'' series, the most notable examples are Fireheart and Tigerclaw, and, [[GenerationXerox coincidentally,]] their mentors, Bluefur and Thistleclaw.
* In the ''Literature/{{Shannara}}'' franchise, Bremen the last of the original Druids, and Brona the [[SorcerousOverlord Warlock Lord]] (who betrayed and destroyed the Druid Order) were this in the {{backstory}}. This was eventually expanded on in ''Literature/FirstKingOfShannara'', where we see that Bremen in particular took this very personally. In ''TheVoyageOfTheJerleShannara'' the Ilse Witch thinks that she and [[TheMentor Walker]] are archenemies but in reality she's been duped, and he wants to save her. A straight example in ''Voyage'' is [[WarriorPrince Elven Prince]] [[ClassicalAntihero Ahren Elessedil]] and [[LizardFolk Mwellret]] [[TheDragon Cree Bega]]. There's just something fundamentally twisted in the tortured relationship between this [[BreakTheCutie broken Elf]] and the sociopathic SmugSnake who [[KickTheDog turned him into]] TheWoobie.
* In ''Literature/TheWheelOfTime'' the Forsaken [[TheDragon Ishamael]] [[spoiler: Later Moridin]] clearly views himself as this to [[TheChosenOne Rand Al'Thor]]. Considering that he's TheVerse's version of TheAntichrist, from a metaphysical standpoint he's not wrong, either. However, another member of [[QuirkyMinibossSquad the Forsaken]] would contest the position- Demandred, who is said to have hated Rand's previous incarnation ''more than anyone has ever hated anything'' and has transferred that hate fully to Rand, making it plain that he sees himself as [[TheOnlyOneAllowedToDefeatYou the only one allowed to defeat him]] [[spoiler: though Moridin makes it plain he won't respect that if his plans call for it]]. Prior to his death, [[TheNapoleon Sammael]] would have put himself up for the title too, though other Forsaken feel he falls well short of Demandred for sheer hatred- yeah, being the main character in a series where ItSucksToBeTheChosenOne means you get ''lots'' of people who want this position. Other characters have them too, usually (but not always) their EvilCounterpart:
** [[LovableRogue Mat]] has [[ImplacableMan the Gholam]].
*** Mat is also considered the counterpart to the Forsaken Balthalmel (since both are gamblers and womanizers), though the two don't really interact. There is also Padain Fain, due to their mutual connection with Shadar Logoth, and Fain once held Mats family captive. [[spoiler: And it is ultimately Mat who takes Fain down.]] Though Fain considers Rand his archenemy (despite hating Mat and Perrin also, adn the Ishamael and the Dark One), and furthermore [[spoiler: Fain kills Perrin's family.]]
** [[OurWerewolvesAreDifferent Perrin]] has [[TheHunter Slayer]].
** [[ExtraordinarilyEmpoweredGirl Egwene]] has [[TyrantTakesTheHelm Elaida]].
** [[TheMedic Nynaeve]] has [[TheSpymaster Moghedien]].
* ''{{Redwall}}'' has had a few examples, but the most obvious are Swartt Sixclaw and Sunflash the Mace from ''Outcast of Redwall''. When Sunflash maims Swartt's trademark sixclawed paw while escaping enslavement, a feud is struck that will haunt them both for their lives. From the time they are teenagers until Swartt's death in late middle age, they are always hunting one another.
* Soviet spymaster Karla to George Smiley in various [[JohnLeCarre John le Carré]] novels.
* In ''Literature/ASongOfIceAndFire'', Cersei Lannister thinks that Tyrion is her worst enemy thanks to a prophecy stating that her she would be strangled to death by the hands of her younger brother. She is utterly convinced in ''A Feast for Crows'' and ''A Dance with Dragons'' that everything going wrong in her life is Tyrion's work.
** More generally, House Stark considers House Lannister to be ''their'' archenemies and the conflict between the two is central to the story. The Lannisters see the Starks more as annoyances, but [[spoiler: between killing Eddard Stark, holding Sansa and (supposedly) Arya Stark hostage, crippling Bran and masterminding the Red Wedding]]...Yeah, ItsPersonal. The Starks thought they were archenemies before, but by this stage several members of the Stark clan exist solely to destroy the Lannister House.
*** More specific examples, Cateyln despises Cersei and blames her for what happened to her husband and children; Arya seems to hate every single one of them but ''especially'' hates Joffrey; Joffrey thinks he is TheRival to Robb Stark (from a purely dynastic point of view, he is right, but Robb completely outclasses him as a warrior and commander, partly because Joffrey is still just a kid); and Robb himself probably saw Jaime as the Lannister he had to beat. On the flip side, the heads of these households, Tywin and Eddard, didn't seem to think about the other that much at all, while Tyrion Lannister has a...complicated relationship with all of them (both the Stark family and his own). The youngest children, on both sides, are treated more like victims of the whole thing.
** Gregor Clegane, the Mountain that Rides, is an AxCrazy [[TheSociopath sociopath]] with a penchant for RapePillageAndBurn, and as such several characters, including his own brother, have sworn to kill him for whatever specific crime he happened to commit against them or their family on any given day.
** Rhaegar Targaryen was highly regarded by most people and generally seen as TheWisePrince by everyone...except Robert Baratheon, who hated him with a such a passion that he not only killed Rhaegar personally in mortal combat, he sworn to kill every single Targaryen he could get his hands on, including their children. Though the practice of slaughtering the kin of rivals to the throne is [[CrapsackWorld not exactly uncommon in this setting]] (and the surviving Targayen children actually ''are'' plotting to overthrow him and his House), it is strongly implied that Robert did this purely out of spite for the Targaryens' in general and Rhaegar in particular.
* Elijah to Queen Jezebel in Literature/TheBible.
* In ''Literature/{{Timeline 191}}'' the United States of America and the Confederate States of America are one another's archenemies, fighting four wars against one another, and spending most of their time when they are not at war preparing for the next one.
* ''Cold Days,'' in ''Literature/TheDresdenFiles'', reveals two factions have this kind of relationship: [[spoiler:the Fae Winter Court against Nemesis, a HatePlague/alien invasion.]] An epic-scale war that has continued for centuries.
* DimeNovel hero Literature/NickCarter's greatest foe was the fiendish Professor Jack Quartz, a hypnotist and vivisectionist.
* The balor Errtu is the self-proclaimed archenemy of [[Literature/TheLegendOfDrizzt Drizzt]]. Errtu claims that no one else [[ThePowerOfHate hates]] Drizzt as much as he does. Errtu is glad that Drizzt is a Dark Elf, a being whose projected lifespan can be measured in centuries, since this means there's a good chance Drizzt will still be alive when Errtu is eventually allowed to leave the Abyss. Every time Errtu finds a way out of the Abyss he makes a beeline for Drizzt. During one of his stays in the Abyss, Errtu took great pleasure in torturing the soul of one of Drizzt's friends. While Drizzt has other foes like the assassin Artemis Entreri and the orc king Obould Many-Arrows, Errtu is far more evil than either of those two and is also the only one who could theoretically hound Drizzt for the rest of his life.
* Professor Moriarty is Literature/SherlockHolmes' Arch Enemy and WorthyOpponent.
** Almost by default, since he only really appears in two stories written by Sir Arthur Conan Doyle.
* In ''Franchise/TheDarkTower'', Walter is Roland's Arch Enemy, but not the BigBad.
* Ernst Stavro Blofeld becomes Literature/JamesBond's Arch Enemy over the course of three books, until Bond himself comes to think of it as a blood feud and refuses to get [=MI6=] involved.
* ''Literature/HarryPotter'':
** Voldemort to Harry. Also jerkass Draco Malfoy and Severus Snape, at least until [[spoiler:Snape's death.]]
** Rita Skeeter to Hermione Granger.
** Bellatrix Lestrange to Neville Longbottom, Hermione Granger and the Weasley family.
** The Malfoy family to the Weasley family.
** Voldemort (and previously, Gellert Grindelwald) to Dumbledore.
* Morjin to Valashu in the ''EaCycle''.
* {{Dracula}} meets his match after 400 years in the person of [[TheHunter Abraham Van Helsing]].
* ''SoonIWillBeInvincible'': After defeating Doctor Impossible and discovering her ties to him, Fatale considers this might make him her Arch Enemy, but is it worth it?
-->I suppose I ought to vow to oppose him forever; make a nemesis issue of it. But it's a little beside the point. ... with [[spoiler: [=CoreFire=]]] back, he's already got a nemesis. I'd have to be a co-nemesis. ... I'm not 100 percent sure what I'm supposed to angry about, if we come down to it.
* Hakeswill in {{Sharpe}} seems to dedicate himself expressly to making Sharpe's life miserable - he has him flogged in pre-{{canon}}, he has Harper flogged after figuring out how close he and Sharpe are, he attempts to rape and [[spoiler: eventually murders]] Sharpe's wife... Sharpe tries and fails to kill him in repeated inventive ways before [[spoiler:he finally gets to give him the coup de grace at his execution]].
** Once Hakeswill had been written out of the novels, this role was arguably taken over by Major Ducos, a French spymaster who is constantly coming up with schemes to hamstring, if not outright stop, the British war effort, as well as to humiliate, discredit and kill Sharpe in the process.
* Lex Luthor (or the Guy who took the name-Like he cared about a copyright infringment suit) thought he was in ''Literature/TalesOfAnMazingGirl''. He was more of a minor threat.
** The Duke of Wellington and NapoleonBonaparte, whom some like to see as historical archenemies, even though they probably did not see themselves that way, show up in the series.
* John Devil, from the eponymous novel by Paul Feval is the Arch Enemy of Inspector Gregory Temple, as well as being one of the earliest super-villains, anticipating the aforementioned Moriarty with about 30 years.
* Carl Peterson was the Arch Enemy of BulldogDrummond, until he was killed in the fourth novel. Afterwards, Carl's mistress, Irma took over his role.
* Ballmeyer, [[spoiler:aka Detective Frederic Larsan]] is the Arch Enemy of Joseph Rouletabille as well as the latter's [[spoiler:biological father]].
* Franny Roote in Reginald Hill's DalzielAndPascoe novels: although Hill dispatches Roote to jail in the series' second novel, ''An Advancement of Learning'', he resurrects him as Pascoe's obsession in ''Arms and the Women'', ''Dialogues of the Dead'', and ''Death's Jest-Book'', then finally elevates him to true Arch Enemy status in ''A Cure for All Diseases''.
* Visser Three to the Literature/{{Animorphs}}.
** He was also Elfangor's Arch Enemy, to an even more [[ItsPersonal personal degree]]. On a lesser scale, [[TortureTechnician Taylor]] is this to [[TheWoobie Tobias]], and [[SixthRangerTraitor David]] sees himself as [[TheBigGuy Rachel's]]. And then there's cosmic archenemies, [[BiggerBad Crayak]] and [[BigGood The Ellimist]]. One could also make the case for [[EvilMatriarch Visser One]] being [[TheLancer Marco]]'s Arch Enemy.
* Chauvelin for the eponymous hero of ''Literature/TheScarletPimpernel'', with generous traces of InspectorJavert and FoeYay.
* In the BackStory of Creator/RobertEHoward's ConanTheBarbarian story "The Phoenix on the Sword", Set was this to Epemitreus. Which is part of why he helps Conan against Thoth-amon, one of Set's votaries.
* The Deaf Man in the ''Literature/EightySeventhPrecinct'' series by Creator/EdMcBain.
* CompanionsQuartet has Kullervo for the main character Connie
* In the ''Literature/WarriorCats'' series, the most notable examples are Fireheart and Tigerclaw, and, [[GenerationXerox coincidentally,]] their mentors, Bluefur and Thistleclaw.
* In the ''Literature/{{Shannara}}'' franchise, Bremen the last of the original Druids, and Brona the [[SorcerousOverlord Warlock Lord]] (who betrayed and destroyed the Druid Order) were this in the {{backstory}}. This was eventually expanded on in ''Literature/FirstKingOfShannara'', where we see that Bremen in particular took this very personally. In ''TheVoyageOfTheJerleShannara'' the Ilse Witch thinks that she and [[TheMentor Walker]] are archenemies but in reality she's been duped, and he wants to save her. A straight example in ''Voyage'' is [[WarriorPrince Elven Prince]] [[ClassicalAntihero Ahren Elessedil]] and [[LizardFolk Mwellret]] [[TheDragon Cree Bega]]. There's just something fundamentally twisted in the tortured relationship between this [[BreakTheCutie broken Elf]] and the sociopathic SmugSnake who [[KickTheDog turned him into]] TheWoobie.
* In ''Literature/TheWheelOfTime'' the Forsaken [[TheDragon Ishamael]] [[spoiler: Later Moridin]] clearly views himself as this to [[TheChosenOne Rand Al'Thor]]. Considering that he's TheVerse's version of TheAntichrist, from a metaphysical standpoint he's not wrong, either. However, another member of [[QuirkyMinibossSquad the Forsaken]] would contest the position- Demandred, who is said to have hated Rand's previous incarnation ''more than anyone has ever hated anything'' and has transferred that hate fully to Rand, making it plain that he sees himself as [[TheOnlyOneAllowedToDefeatYou the only one allowed to defeat him]] [[spoiler: though Moridin makes it plain he won't respect that if his plans call for it]]. Prior to his death, [[TheNapoleon Sammael]] would have put himself up for the title too, though other Forsaken feel he falls well short of Demandred for sheer hatred- yeah, being the main character in a series where ItSucksToBeTheChosenOne means you get ''lots'' of people who want this position. Other characters have them too, usually (but not always) their EvilCounterpart:
** [[LovableRogue Mat]] has [[ImplacableMan the Gholam]].
*** Mat is also considered the counterpart to the Forsaken Balthalmel (since both are gamblers and womanizers), though the two don't really interact. There is also Padain Fain, due to their mutual connection with Shadar Logoth, and Fain once held Mats family captive. [[spoiler: And it is ultimately Mat who takes Fain down.]] Though Fain considers Rand his archenemy (despite hating Mat and Perrin also, adn the Ishamael and the Dark One), and furthermore [[spoiler: Fain kills Perrin's family.]]
** [[OurWerewolvesAreDifferent Perrin]] has [[TheHunter Slayer]].
** [[ExtraordinarilyEmpoweredGirl Egwene]] has [[TyrantTakesTheHelm Elaida]].
** [[TheMedic Nynaeve]] has [[TheSpymaster Moghedien]].
* ''{{Redwall}}'' has had a few examples, but the most obvious are Swartt Sixclaw and Sunflash the Mace from ''Outcast of Redwall''. When Sunflash maims Swartt's trademark sixclawed paw while escaping enslavement, a feud is struck that will haunt them both for their lives. From the time they are teenagers until Swartt's death in late middle age, they are always hunting one another.
* Soviet spymaster Karla to George Smiley in various [[JohnLeCarre John le Carré]] novels.
* In ''Literature/ASongOfIceAndFire'', Cersei Lannister thinks that Tyrion is her worst enemy thanks to a prophecy stating that her she would be strangled to death by the hands of her younger brother. She is utterly convinced in ''A Feast for Crows'' and ''A Dance with Dragons'' that everything going wrong in her life is Tyrion's work.
** More generally, House Stark considers House Lannister to be ''their'' archenemies and the conflict between the two is central to the story. The Lannisters see the Starks more as annoyances, but [[spoiler: between killing Eddard Stark, holding Sansa and (supposedly) Arya Stark hostage, crippling Bran and masterminding the Red Wedding]]...Yeah, ItsPersonal. The Starks thought they were archenemies before, but by this stage several members of the Stark clan exist solely to destroy the Lannister House.
*** More specific examples, Cateyln despises Cersei and blames her for what happened to her husband and children; Arya seems to hate every single one of them but ''especially'' hates Joffrey; Joffrey thinks he is TheRival to Robb Stark (from a purely dynastic point of view, he is right, but Robb completely outclasses him as a warrior and commander, partly because Joffrey is still just a kid); and Robb himself probably saw Jaime as the Lannister he had to beat. On the flip side, the heads of these households, Tywin and Eddard, didn't seem to think about the other that much at all, while Tyrion Lannister has a...complicated relationship with all of them (both the Stark family and his own). The youngest children, on both sides, are treated more like victims of the whole thing.
** Gregor Clegane, the Mountain that Rides, is an AxCrazy [[TheSociopath sociopath]] with a penchant for RapePillageAndBurn, and as such several characters, including his own brother, have sworn to kill him for whatever specific crime he happened to commit against them or their family on any given day.
** Rhaegar Targaryen was highly regarded by most people and generally seen as TheWisePrince by everyone...except Robert Baratheon, who hated him with a such a passion that he not only killed Rhaegar personally in mortal combat, he sworn to kill every single Targaryen he could get his hands on, including their children. Though the practice of slaughtering the kin of rivals to the throne is [[CrapsackWorld not exactly uncommon in this setting]] (and the surviving Targayen children actually ''are'' plotting to overthrow him and his House), it is strongly implied that Robert did this purely out of spite for the Targaryens' in general and Rhaegar in particular.
* Elijah to Queen Jezebel in Literature/TheBible.
* In ''Literature/{{Timeline 191}}'' the United States of America and the Confederate States of America are one another's archenemies, fighting four wars against one another, and spending most of their time when they are not at war preparing for the next one.
* ''Cold Days,'' in ''Literature/TheDresdenFiles'', reveals two factions have this kind of relationship: [[spoiler:the Fae Winter Court against Nemesis, a HatePlague/alien invasion.]] An epic-scale war that has continued for centuries.
* DimeNovel hero Literature/NickCarter's greatest foe was the fiendish Professor Jack Quartz, a hypnotist and vivisectionist.
* The balor Errtu is the self-proclaimed archenemy of [[Literature/TheLegendOfDrizzt Drizzt]]. Errtu claims that no one else [[ThePowerOfHate hates]] Drizzt as much as he does. Errtu is glad that Drizzt is a Dark Elf, a being whose projected lifespan can be measured in centuries, since this means there's a good chance Drizzt will still be alive when Errtu is eventually allowed to leave the Abyss. Every time Errtu finds a way out of the Abyss he makes a beeline for Drizzt. During one of his stays in the Abyss, Errtu took great pleasure in torturing the soul of one of Drizzt's friends. While Drizzt has other foes like the assassin Artemis Entreri and the orc king Obould Many-Arrows, Errtu is far more evil than either of those two and is also the only one who could theoretically hound Drizzt for the rest of his life.
