Doctor Strange

The Doctor Strange Sequel is directed by Sam Raimi, with the Sequel confirming to have Alternate Self Variants to appear in the film, and since Raimiverse Spider-Man has appeared in No Way Home, it would be surprising for him to appear in The Multiverse of Madness.

Since the Sequel has confirmed to have Alternate Self Variants to appear in the film, as Webbverse Spider-Man did appear in No Way Home, it would be surprising for him to appear in The Multiverse of Madness.

Since the Multiverse of Madness is also going to have Heroes such as America Chavez introduced, it is implied that it will also introduce the MCU X-Men.

Since the Multiverse of Madness is also going to have Heroes such as America Chavez introduced, it is implied that it will also introduce the MCU Fantastic Four.

Since the Multiverse of Madness is also going to have Heroes such as America Chavez introduced, it is implied that it will also introduce the Deadpool, except in his first appearance in the Marvel Cinematic Universe.

Despite having powers that are dangerous, she did helped save the world such as helping the Avengers stop Ultron, helping Steve while joining his side and stopping Helmut Zemo, Helped stop 2014 Thanos from turning the world into his own image, rescued her children from being held hostage by Agatha, saved the S.W.O.R.D. from falling to there deaths, and even forgave Monica while considering her as a friend.

Shuma was reported to appear in The Multiverse of Madness, it is implied to he will serve as the main antagonist of the sequel film. Presumably by trying to conquer the Multiverse.

Mordo did say to Strange in the trailer, that the one who is the greatest of the Muktiverse is his Evil Counterpart. this might foreshadow his role as the main antagonist in the sequel film.

Well, sine all three of them are enemies of Doctor Strange, they do appear to have one thing in common, trying to destroy magic from being used.