The Hole in the Ozone Layer: Proof of massive human change?

Which is a Greenhouse gas.

Albeit the most benign one.

But a greenhouse gas isn't very relevant to this discussion, because, while there are a few greenhouse gases that also break down O3, water vapor isn't one of them.

@OP, technically it's not "proof" per say, but a strong indication that human activity contributes to the effect.

To outline the process for reference(if my old ecology class notes are correct), once your little bastard CFC molecule makes his escape from his aerosol can prison, he gets pretty lonely, and wouldn't you know it, this hot little UV ray strolls along, flaunting her UV ass at him as UV rays often do. They get it on, but the UV ray proves to be a little more than our CFC can handle, and she breaks off one of his chlorine atoms and leaves him feeling inadequate.

Now the little chlorine atom is all on his own, and already he's checking out the prospects. These Nitrogen chicks are everywhere, and even though he's a chlorine atom, he has standards, man. And these Argon girls are waaay too chunky for his liking. Now, these oxygen girls have it going on, but they're all taken. This pisses our chlorine molecule off royally. Earth and all her creation give him shit, and the oxygen molecules are always like "Go back to Sodium where you belong, loser!"

This really makes him mad. Oxygen is going to royally pay. Here comes this snobby little fellow Ozone and his little Oxygen OT3. Chlorine swoops in outta nowhere, valence blazing so fiercely that van der Waals and his weak little interactions jump in his grave. An Oxygen is finally his to boss around for once, and Ozone is reduced to some whiny little O2 punk.

The Ozones don't let this go unforgiven. This is O3 turf, and no chlorine punk is going to be getting away this easily. They send Free Oxygen, this Axe-Crazy bastard, to beat the frikken leptons outta Chlorine, and in return Free Oxygen gets to join the O2 caste.

But in the end, lysing begats lysing, and Chlorine goes on to act on his hatred of Ozone. He dies happily though, knowing that in the end only one Chlorine took hundreds of thousands of Ozones with him.

That's a great way of putting it.

Yeah, the Ozone layer issue is something separated from global warming. Much less complicated, and it's pretty much settled chemistry.

Note. Just because I think that weather/climate are very complicated models, doesn't mean that I think that global warming is a "hoax". It's the best science we have right now on the subject, and we should act accordingly.

Especially since the climate will screw you whether you believe it is natural or not. We're already seeing lots of climate change induced issues around the world, and it's only going to get worse in the foreseeable future.