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* ''WesternAnimation/TheVentureBrothers'': In "Past Tense", Mike Sorayama's grievance with his former college friend Baron Ünderbheit is that Ünderbheit sold him some fake weed that turned out to be oregano. Unfortunately, Mike was allergic to oregano and suffered a near-fatal reaction.

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* ''WesternAnimation/TheVentureBrothers'': In "Past Tense", Mike Sorayama's grievance with his former college friend Baron Ünderbheit is that Ünderbheit sold him some fake weed that turned out to be oregano. Unfortunately, Mike was allergic to oregano and [[DeadlyPrank suffered a near-fatal reaction.reaction]].
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* ''WesternAnimation/TheVentureBrothers'': Unfortunately the victim of the prank was allergic to oregano.

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* ''WesternAnimation/TheVentureBrothers'': Unfortunately the victim of the prank In "Past Tense", Mike Sorayama's grievance with his former college friend Baron Ünderbheit is that Ünderbheit sold him some fake weed that turned out to be oregano. Unfortunately, Mike was allergic to oregano.oregano and suffered a near-fatal reaction.
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* Happens in ''Film/{{Eurotrip}}'' when two characters walk into a Jamaican coffee shop in Amsterdam and order what they think are hash brownies, hallucinating wildly until they're snapped back to reality when told by the waiter they're just regular brownies.

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* Happens in ''Film/{{Eurotrip}}'' when two characters walk into a Jamaican coffee bakery shop in Amsterdam and order what they think are hash brownies, brownies. They start hallucinating wildly wildly, even believing that they may have been tainted with something and accusing the staff of serving them bad hash brownies, until they're snapped back to reality when told by the waiter they're just regular brownies.
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* ''Fanfic/ACertainDrollHivemind'': From "Guest Entry - Mikoto": one of Misaka's thoughts to do to Uiharu:
--> her precinct uses some really nasty frequency jumping algorithms and encryption tricks that makes it harder than Anti-Skill's stuff. Hmm. Note to self - buy Uiharu some rum and raisin ice cream and see if that has a placebo effect that gets her tipsy so she talks about how she implemented it. It's starting to get on my nerves that I can't reliably listen in.

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* ''Fanfic/ACertainDrollHivemind'': From "Guest Entry - Mikoto": one of Misaka's thoughts Mikoto, annoyed that she can't just hack into Kuroko's radio chatter to do to Uiharu:
--> her precinct uses
figure out when she needs help, wonders if she can trick Uiharu (Kuroko's security expert) into giving up some really nasty frequency jumping algorithms and encryption tricks that makes it harder than Anti-Skill's stuff. Hmm.secrets this way.
-->Hmm.
Note to self - buy Uiharu some rum and raisin ice cream and see if that has a placebo effect that gets her tipsy so she talks about how she implemented it. It's starting to get on my nerves that I can't reliably listen in.
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* ''ComicBook/SpiderMan2099'': PlayedForDrama. Tyler Stone laced Miguel's drink with a drug that mimicked the effects of the instantly addictive and extremely dangerous [[FantasticDrug Rapture]], except that this drug would flush out of his system in three days. Unfortunately, Miguel thought it was the actual drug, and because it works by bonding to the user's DNA, Miguel proceeded to try and alter his DNA to get rid of its effects, accidentally becoming Spider-Man in the process due to a third party sabotaging him. He is NOT happy to find out the drug was a fake.
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* In ''VideoGame/FinalFantasyXIV'', [[UltimateBlacksmith Gerolt Blackthorn]] is working for [[FictionFiveHundred Godbert Manderville]] to create a new set of powerful weapons, [[TeethClenchedTeamwork but he hates every second of it]]. Sensing Gerolt's ire with him, Godbert invites him to air out his grievences over some fine Hanish spirits. [[TheAlcoholic Gerolt's never one to pass on a drink]], and so the two get to talking and drinking. Many rounds later, Gerolt is so plastered that he's hallucinating. Once he's staggered away back to his forge, Godbert reveals that part way through the drinking, he had subtilty swapped their alcohol for carrot juice out of concern for Gerolt's health, meaning most of Gerolt's intoxication is placebo (or perhaps muscle memory).

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* In ''VideoGame/FinalFantasyXIV'', [[UltimateBlacksmith Gerolt Blackthorn]] is working for [[FictionFiveHundred [[Fiction500 Godbert Manderville]] to create a new set of powerful weapons, [[TeethClenchedTeamwork but he hates every second of it]]. Sensing Gerolt's ire with him, Godbert invites him to air out his grievences over some fine Hanish spirits. [[TheAlcoholic Gerolt's never one to pass on a drink]], and so the two get to talking and drinking. Many rounds later, Gerolt is so plastered that he's hallucinating. Once he's staggered away back to his forge, Godbert reveals that part way through the drinking, he had subtilty swapped their alcohol for carrot juice out of concern for Gerolt's health, meaning most of Gerolt's intoxication is placebo (or perhaps muscle memory).
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* In ''VideoGame/FinalFantasyXIV'', [[UltimateBlacksmith Gerolt Blackthorn]] is working for [[FictionFiveHundred Godbert Manderville]] to create a new set of powerful weapons, [[TeethClenchedTeamwork but he hates every second of it]]. Sensing Gerolt's ire with him, Godbert invites him to air out his grievences over some fine Hanish spirits. [[TheAlcoholic Gerolt's never one to pass on a drink]], and so the two get to talking and drinking. Many rounds later, Gerolt is so plastered that he's hallucinating. Once he's staggered away back to his forge, Godbert reveals that part way through the drinking, he had subtilty swapped their alcohol for carrot juice out of concern for Gerolt's health, meaning most of Gerolt's intoxication is placebo (or perhaps muscle memory).
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* ''WesternAnimation/BobsBurgers'': In "Bad Tina" Tina's new friend, 'bad girl' Tammy, invites herself over when the parents are out, along with Jimmy Jr. and Zeke. She sneaks a bottle of margarita mix from the liquor cabinet and proceeds to party. The kids are getting high, but mostly from a sugar buzz -- Louise says her mom uses the stuff as hummingbird food.

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* ''WesternAnimation/BobsBurgers'': In "Bad Tina" Tina's new friend, 'bad girl' Tammy, invites herself over when the parents are out, along with Jimmy Jr. and Zeke. She sneaks a bottle of margarita mix from the liquor cabinet and proceeds to party. The kids are getting high, but mostly Thinking it's alcoholic, Tammy refers to it as "the heavy stuff" and that "she can totally feel it" after taking a drink from a sugar buzz it. -- Louise says her mom uses the stuff as hummingbird food.
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* ''Series/OrangeIsTheNewBlack'': in season 3 we find out why Flaco ended up in jail. To make money in high school, she printed fake LSD tabs and sold them to her classmates, who would all fake being high around eachother. Things turned sour when she sold some to a depressed classmate, who took the lack of effects as a sign that everything is meaningless, and jumps off the roof the next day, and Flaco is then arrested for selling him the fake drugs.
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* In an ''Literature/TheUnexploredSummonBloodSign'' scene, Sinceria is drinking champagne when her preteen daughter, Olivia, says she wants some too. Their maids, who are very good at their job, pour Olivia a glass of sparkling grape juice. It has a fancy label, so she doesn't notice a thing.
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* Parodied in ''Manga/The100GirlfriendsWhoReallyReallyReallyReallyReallyLoveYou''. Protagonist Rentarou Aijou suggests that he and his harem do a mock drinking party with the non-alcoholic Serious Kids Beer, but after the will of the author explains that most of the cast is too young for that and [[YouWannaGetSued they'll get in trouble for depicting drunk teens in the 2010s]], Rentarou engineers things so that everyone ''acts'' as drunk as possible without actually being drunk (turning up the humidity, doing exercises to make everyone dizzy, giving everyone fruit drinks, etc). The result is a chapter where we see what the harem would do if they were totally sloshed, but with a panel-by-panel reminder that they are totally kosher by the law's standards.
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* Parodied in ''Manga/The100GirlfriendsWhoReallyReallyReallyReallyReallyLoveYou''. Protagonist Rentarou Aijou suggests that he and his harem do a mock drinking party, but after the will of the author explains that most of the cast is too young for that and [[YouWannaGetSued they'll get in trouble for depicting drunk teens in the 2010s]], Rentarou engineers things so that everyone ''acts'' as drunk as possible without actually being drunk (turning up the humidity, doing exercises to make everyone dizzy, giving everyone fruit drinks, etc). The result is a chapter where we see what the harem would do if they were totally sloshed, but with a panel-by-panel reminder that they are totally kosher by the law's standards.

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* Parodied in ''Manga/The100GirlfriendsWhoReallyReallyReallyReallyReallyLoveYou''. Protagonist Rentarou Aijou suggests that he and his harem do a mock drinking party, party with the non-alcoholic Serious Kids Beer, but after the will of the author explains that most of the cast is too young for that and [[YouWannaGetSued they'll get in trouble for depicting drunk teens in the 2010s]], Rentarou engineers things so that everyone ''acts'' as drunk as possible without actually being drunk (turning up the humidity, doing exercises to make everyone dizzy, giving everyone fruit drinks, etc). The result is a chapter where we see what the harem would do if they were totally sloshed, but with a panel-by-panel reminder that they are totally kosher by the law's standards.
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* Parodied in ''Manga/The100GirlfriendsWhoReallyReallyReallyReallyReallyLoveYou''. Protagonist Rentarou Aijou suggests that he and his harem do a mock drinking party, but after the will of the author explains that most of the cast is too young for that and [[YouWannaGetSued they'll get in trouble for depicting drunk teens in the 2010s]], Rentarou engineers things so that everyone ''acts'' as drunk as possible without actually being drunk (turning up the humidity, doing exercises to make everyone dizzy, giving everyone fruit drinks, etc). The result is a chapter where we see what the harem would do if they're totally sloshed, but with a panel-by-panel reminder that they are totally kosher by the law's standards.

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* Parodied in ''Manga/The100GirlfriendsWhoReallyReallyReallyReallyReallyLoveYou''. Protagonist Rentarou Aijou suggests that he and his harem do a mock drinking party, but after the will of the author explains that most of the cast is too young for that and [[YouWannaGetSued they'll get in trouble for depicting drunk teens in the 2010s]], Rentarou engineers things so that everyone ''acts'' as drunk as possible without actually being drunk (turning up the humidity, doing exercises to make everyone dizzy, giving everyone fruit drinks, etc). The result is a chapter where we see what the harem would do if they're they were totally sloshed, but with a panel-by-panel reminder that they are totally kosher by the law's standards.
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* Parodied in ''Manga/The100GirlsWhoReallyReallyReallyReallyReallyLoveYou''. Protagonist Rentarou Aijou suggests that he and his harem do a mock drinking party, but after the will of the author explains that most of the cast is too young for that and [[YouWannaGetSued they'll get in trouble for depicting drunk teens in the 2010s]], Rentarou engineers things so that everyone ''acts'' as drunk as possible without actually being drunk (turning up the humidity, doing exercises to make everyone dizzy, giving everyone fruit drinks, etc). The result is a chapter where we see what the harem would do if they're totally sloshed, but with a panel-by-panel reminder that they are totally kosher by the law's standards.

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* Parodied in ''Manga/The100GirlsWhoReallyReallyReallyReallyReallyLoveYou''.''Manga/The100GirlfriendsWhoReallyReallyReallyReallyReallyLoveYou''. Protagonist Rentarou Aijou suggests that he and his harem do a mock drinking party, but after the will of the author explains that most of the cast is too young for that and [[YouWannaGetSued they'll get in trouble for depicting drunk teens in the 2010s]], Rentarou engineers things so that everyone ''acts'' as drunk as possible without actually being drunk (turning up the humidity, doing exercises to make everyone dizzy, giving everyone fruit drinks, etc). The result is a chapter where we see what the harem would do if they're totally sloshed, but with a panel-by-panel reminder that they are totally kosher by the law's standards.
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* Parodied in ''Manga/The100GirlsWhoReallyReallyReallyReallyReallyLoveYou''. Protagonist Rentarou Aijou suggests that he and his harem do a mock drinking party, but after the will of the author explains that most of the cast is too young for that and [[YouWannaGetSued they'll get in trouble for depicting drunk teens in the 2010s]], Rentarou engineers things so that everyone ''acts'' as drunk as possible without actually being drunk (turning up the humidity, doing exercises to make everyone dizzy, giving everyone fruit drinks, etc). The result is a chapter where we see what the harem would do if they're totally sloshed, but with a panel-by-panel reminder that they are totally kosher by the law's standards.
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* Raj on the ''Series/TheBigBangTheory'' needs alcohol before he can talk to women. In one episode he has a beer and starts hitting on Creator/SummerGlau, until Howard points out the beer was non-alcoholic, and Raj [[CentipedesDilemma can't continue]].

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* Raj on in the earlier episodes of ''Series/TheBigBangTheory'' needs alcohol before he can talk to women. In one episode he has a beer and starts hitting on Creator/SummerGlau, until Howard points out the beer was non-alcoholic, and Raj [[CentipedesDilemma can't continue]].
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* ''Webcomic/TwoLumps'': Snooch made the mistake of watching a special on rock stars and copying their cocaine use ... [[http://twolumps.net/d/20070801.html sort of.]]

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* ''Webcomic/TwoLumps'': Snooch made the mistake of watching a special on rock stars and copying their cocaine use ... [[http://twolumps.net/d/20070801.html [[https://twolumps.net/comic/20070801-2/ sort of.]]
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* In ''Anime/GreatPretender,'' the protagonists Makoto and Laurent are trying to [[StealingFromCrooks con a mobster]] into buying a new drug called "Sakura Magic," which Makoto accidentally ingests. His vision blurs, he becomes paranoid, and he tries to violently escape the mobster's house and has to be physically held down. But Sakura Magic turns out to be literally just candy--''that's the con''--and it was all placebo making Makoto wig out.

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* In ''Anime/GreatPretender,'' the protagonists Makoto and Laurent are trying to [[StealingFromCrooks [[KarmicThief con a mobster]] into buying a new drug called "Sakura Magic," Magic", which Makoto accidentally ingests. His vision blurs, he becomes paranoid, and he tries to violently escape the mobster's house and has to be physically held down. But Sakura Magic turns out to be literally just candy--''that's candy -- ''that's the con''--and con'' -- and it was all placebo making Makoto wig out.
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* Downplayed in ''Manga/KaguyaSamaLoveIsWar'' when Iino ends up consuming an entire box of whiskey chocholates. She is genuinely drunk, but it's only after drinking a bottle of water that Onodera claimed was alcohol that she loses consciousness.
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* Creator/Steve Martin at one time declared that he'd gotten into some pills that had him higher than a kite. They were called . . . "Placebo."

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* Creator/Steve Martin Creator/SteveMartin at one time declared that he'd gotten into some pills that had him higher than a kite. They were called . . . "Placebo."
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* In ''Anime/GreatPretender,'' the protagonists Makoto and Laurent are trying to [[StealingFromCrooks con a mobster]] into buying a new drug called "Sakura Magic," which Makoto accidentally ingests. His vision blurs, he becomes paranoid, and he tries to violently escape the mobster's house and has to be physically held down. But Sakura Magic turns out to be literally just candy--''that's the con''--and it was all placebo making Makoto wig out.
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* Creator/Steve Martin at one time declared that he'd gotten into some pills that had him higher than a kite. They were called . . . "Placebo."
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* In ''Series/ICarly2021'' episode "i'M Wild and Crazy", Carly asks Harper to take her out for a wild night, drugs, alcohol and so forth. Harper gives Carly a drug called "ACD" and Carly spends the night drinking and doing crazy stuff such as kissing a stranger and getting a tattoo. After they get placed in mall jail, Carly takes a breathalyzer test and her blood alcohol level is 0.0. Harper reveals that she ordered non-alcoholic drinks for Carly and the ACD pill was just a multivitamin. As a bonus, they guy she kissed was Harper's dentist and the tattoo was temporary

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* In ''Series/ICarly2021'' episode "i'M Wild and Crazy", Carly asks Harper to take her out for a wild night, drugs, alcohol and so forth. Harper gives Carly a drug called "ACD" and Carly spends the night drinking and doing crazy stuff such as kissing a stranger and getting a tattoo. After they get placed in mall jail, Carly takes a breathalyzer test and her blood alcohol level is 0.0. Harper reveals that she ordered non-alcoholic drinks for Carly and the ACD pill was just a multivitamin. As a bonus, they the guy she kissed was Harper's dentist and the tattoo was temporary

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