| 1 | * ActorSharedBackground: Creator/DanielSunjata really ''is'' a 9/11 Truther in real life. This was the inspiration for Franco's political views in the show. |
| 2 | * CastTheExpert: Creator/JackMcGee (Chief Jerry) was a real-life FDNY firefighter in the Bronx, before moving to Hollywood to become an actor. |
| 3 | ** Many of the extras were retired or active FDNY firemen who worked on the show on their days off. |
| 4 | * DawsonCasting: This is averted with the young actors playing Tommy's children, but an unusual example seems to take place when when Jerry Adler joins the cast in season 4 at the age of 78; his character is an elderly man, but since he still works a regular shift in a firehouse he realistically must be much younger than the actor playing him. |
| 5 | * IAmNotSpock: Callie Thorne, Sheila Keefe's actress, mentioned in an interview that fans act wary when they meet her, expecting her to be as crazy as the character she plays. |
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