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1!Per wiki policy, Administrivia/SpoilersOff applies here and all spoilers are unmarked. Administrivia/YouHaveBeenWarned.
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3* Dana's fate. Throughout the game, it's shown that despite his faults, Alex does [[MoralityPet genuinely care for his sister]]. On the other hand, her life has been turned upside-down; Blackwatch tried to drag her off for interrogation, she's helping Alex get to the AwfulTruth and finding out some pretty nasty secrets. Then, she finds out her brother has been eating people alive, rightly, she's terrified of him. When he returns later, she forgives him, but still seems terrified. Then she is kidnapped by a Leader Hunter and rendered comatose by whatever Greene did to her. And it's revealed that Alex never cared about her; she was just a pawn in his plans. The player character is a viral doppelganger of her brother; even though he does care about her, he's still a man-eating abomination. And she might be infected...
4** The clearest moment this all comes across is when Alex comes in, staggering from the parasite, Dana starts pulling up information to help him - and Alex says something he couldn't possibly know. When she demands clarification, he makes an increasingly creepy rambling speech about how he ''needs'' to kill, needs these minds inside him, how ''right'' it feels...all while Dana is backing away from him, looking more and more terrified. ''Finally'' he realizes how scared she is (when he has her backed up against her desk), eases off, looks genuinely contrite and reaches out to stroke her cheek. She won't let him. He leaves. As bad as Alex is, he loves his sister...but he's not human enough to help her.
5** Everything about the In-Game Alex's relationship with Dana is absolutely ''heartbreaking'' when you take into account that he's ''not'' Alex Mercer, he's a sentient virus wearing his form and he ''still'' loves her more than the actual Alex Mercer did. Virus Alex is, while terrifying, protective of Dana and caring about her state. The ''real'' Alex used her when it was convenient and was completely uncaring that she'd be caught in the crossfire when he unleashed the Blacklight Virus.
6* Alex's first few minutes of gameplay are this after the [[ATasteOfPower flash forward.]] He wakes up in a morgue with a giant biohazard logo on the door about to be carved open, only to see the morticians gunned down by FacelessGoons who then gun ''him'' down. After surviving much to his horror as he realizes that something's happened to him, he bolts only to get chased by an ''attack helicopter'' firing wildly at him as he sprints down the streets, culminating in him catching a flying car by instinct and ''bellowing'' a demand for an explanation for what the soldiers want with him before hurling the car into the copter, killing the pilot and the dropping troops. ''Then'', he gets chased by more soldiers and copters and this all leads to his first traumatic experience of ''consuming'' a person. Then the above hostage situation with Dana happens, he goes back to his apartment only for it to get ''blown up'' and spends the rest of the game on the run. Not a great day overall.
7** Considering the game's ''massive'' body count, it's somewhat chilling to see ItGetsEasier in full effect. After his first series of kills during the escape from the morgue, Alex sounds ''horrified'' at what he's done.
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