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3%% This page has been alphabetized. Please add new examples in the correct order. Thanks!
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6
7->'''Arthur:''' What do we do now?\
8'''The Tick:''' Well, we find the vegetable villain who did this to me and get the antidote!\
9'''Arthur:''' There's an ''antidote''?\
10'''The Tick:''' Villains always have antidotes... They're funny that way.
11-->-- ''WesternAnimation/TheTick''
12
13One of the characters gets poisoned or sick, and there's a very rare [[MagicAntidote cure]] for them. May be done by the villain, who will oppose the remaining heroes in getting the antidote, or else is {{blackmail}}ing the heroes into doing something for them. In which case the villain will usually be CarryingTheAntidote.
14
15Not ''quite'' a DeathTrap on the part of the villain, but related in being needlessly complicated. If they were able to inject someone with a poison that's curable with a MacGuffin, why didn't they just use an instantly lethal means or use it on the heroes before? A bullet instead of a dart, or a poison that would instantly kill someone? One answer suggests that in this one situation, they aren't {{Genre Blind|ness}}: a bullet would miss while a dart wouldn't. Another has the villain deliberately not killing the target; he or she wouldn't mind if the target dies, of course, but it's more important to have the heroes busy looking for or getting the cure while the Master Plan unfolds. Or, if the aim is blackmail, instant lethality would likely destroy the culprit's leverage over the heroes.
16
17In the case the sickness or poison is not related to the villain at all, the cure to it may be rare or hard to get, especially if you're dealing with MysticalPlague or other kinds of supernatural sickness. And that's if they know if there's even a cure to it at all -- occasionally, the struggle is in ''making'' a cure that works.
18
19Can be a form of AfterActionHealingDrama. Supertrope to PoisonAndCureGambit. Compare HealthcareMotivation and SavedByThePhlebotinum. Contrast AfterActionPatchup and ThereIsNoCure. Not to be confused with [[VideoGame/FindTheCure the video game]].
20----
21!!Examples:
22
23[[foldercontrol]]
24
25[[folder:Anime & Manga]]
26* Guts' current quest in ''Manga/{{Berserk}}'' has him seeking Puck's homeworld of Elfhelm in hopes that the King can cure Casca's post-Eclipse insanity.
27* ''Manga/CaseClosed'':
28** Conan is trying to find the poison he was given, because if he finds a sample, TheProfessor living next door might be able to make a cure. A character who shows up later and is the ''creator'' of said poison is also working on a cure, but unfortunately she lost most of her research and thus doesn't have a lot to go on.
29*** Ai/Shiho later manages to create prototypes of the antidote that allow the shrunken person to regain their original body for a short amount of time. However, the more often the shrunken uses it, the less effective it becomes and the active duration shortens with each use, as the shrunken becomes more resistant to the antidote. The prototypes are meant to be used for emergency cases. So far, Shinichi has taken the prototypes in four separate cases, and Shiho herself has taken it once.
30** [[spoiler:It later turns out that there's another survivor of said poison: Sera's mother Mary. Sera's other goal (aside from finding her brother Shuu) is finding the antidote]].
31* One chapter of ''Manga/DeliciousInDungeon'' involves Laios, Senshi, and Chilchuck trying to find a cure for Marcille after she is [[TakenForGranite turned to stone]] by a cockatrice.
32* ''Manga/DemonSlayerKimetsuNoYaiba'': Tamayo tasks Tanjiro into collecting the blood samples of the Twelve Demon Moons to counteract Muzan's cells within Nezuko and other Demons, if possible.
33* ''Manga/DrStone'': One of the first story arcs is inventing sulfa drugs to cure Ruri's pneumonia. Later, Senku's goal is to save [[spoiler:Tsukasa]] after he is mortally wounded. Because the wounds are lethal, the only way to cure him is to petrify and restore him, so Senku sets off to find whatever petrified all of humanity.
34* The overall mission of the Elric brothers in ''Manga/FullmetalAlchemist'' is essentially this, although the problem isn't technically a disease; the Elrics tampered in God's domain, and as a result, Ed lost AnArmAndALeg and Al is a spirit anchored to a giant suit of AnimatedArmour, so they're looking for a way to restore themselves. Unusually, they find one possible way bright and early, but it's PoweredByAForsakenChild and neither of the brothers is down with that. [[spoiler:Eventually, they find that the cure is a BargainWithHeaven: Al trades the blood seal keeping him tied to his armour and away from his body in Limbo for restoring Ed's arm, and Ed [[{{Depower}} forfeits his alchemy forever]] to get Al's body ''out'' of Limbo. Ed never gets his leg back, though.]]
35* ''Anime/GingaNagareboshiGin'' has an episode where the Ohu dogs fall victim to a poison trap from the Iga ninja Clan. When the poison threatens to blind Ben for life, the Iga clan leader, Akame, [[MyGodWhatHaveIDone feels guilty about this]] and decides to find the herbs that can cure the poison.
36* In ''Anime/HetaliaAxisPowers'', Spain gets sick because of his economic problems and his ex-pupil Romano searches for a cure, even recurring to TheMafia for help. When he returns, though, Spain's economy is better so he's healthy.
37* Kyrie and Iris travel to Earth in ''Anime/MagicalGirlLyricalNanohaReflection'' to find the Examia in the hopes that it can be used to cure both Kyrie's father and help with Eltria's reforestation. [[spoiler:Well, Kyrie does anyways. Iris just wants to get revenge on Yuri.]]
38* In ''Anime/MonsterRancher'', Holly gets sick from Black Worm poison due to TakingTheBullet for Tiger. Hare knows the cure is Natsume Berries but doesn't know where to find them, so Tiger goes off to search by himself. Captain Black Worm ambushes Tiger where the berries grow while the other heroes hide from the Black Worm subordinates.
39* In ''Anime/MujinWakuseiSurvive'', Sharla and Chako have to find medicinal herbs to cure Luna's fever.
40** And later, upon arriving on the mainland, the cast has to find medicine for HumanoidAlien Adam.
41* Subverted to tragic effect in ''Manga/OnePiece''; Chopper risks his life to find a mushroom which he believed was a panacea that would cure his mentor's illness. However, he was mistaken and it was actually a highly poisonous mushroom... which his mentor proceeded to eat, grinning, knowing its nature.
42* Used in ''Manga/PetShopOfHorrors'', when Totetsu is shot and Leon must find Count D to learn what type of blood is needed for a transfusion. [[spoiler:All is put well in the end when D's father secretly comes to see the animal and tells the doctors what sort of blood to use.]]
43* ''Anime/PokemonTheSeries'':
44** During the [[Anime/PokemonTheOriginalSeries Orange Islands arc]], Ash and Tracey fell victim to a Vileplume's Stun Spore, and Misty had to go out to find a cure for the resulting paralysis. In the same episode, Jessie also fell victim to the same Vileplume's Stun Spore, leaving James and Meowth to find the same cure as Misty.
45** At the end of the ''[[Anime/PokemonTheSeriesXY XY]]'' arc's Mega Evolution specials, a Chespin belonging to Mairin, the deuteragonist, falls into a coma. Alain, the protagonist, had previously told Mairin to stay away from him and blames himself for her Chespin's condition. He is told that the Mega Evolution energy he was gathering for Lysandre would undo the coma, so Alain resolves to finish the task, which leads up to his appearance in the main anime. [[spoiler:It's all a lie. Lysandre uses the Mega Evolution energy to enslave Zygarde in order to bring Team Flare's goal of creating a new world by destroying the old one into fruition.]]
46* ''Manga/RanmaOneHalf''
47** The Moxibustion Arc in the manga/anime ''Manga/RanmaOneHalf''. The wicked Happōsai hits Ranma with the Weakness Moxibustion, which makes the strongest man as weak as a toddler. They discover that Happōsai has the ancient scroll with the cure and spend the entire arc training to fight him to get the chart.
48** Whenever Ranma finds out about something that might cure his curse. Of course, FailureIsTheOnlyOption, so every time a cure for the curse is found, it either doesn't work or is lost before it can be used.
49* ''Manga/SnowWhiteWithTheRedHair'': When Shirayuki, Ryuu and [[spoiler:Izana]] visit Lyrias children are falling ill with something that is dropping their body temperatures, paralyzing their muscles and leaving them with bruise-like swirls on their bodies. The source isn't known and by the time they do find a matching description adults are also falling ill and it is described as something which took out over half of the population in the city in which it last appeared so Shirayuki, Ryuu and the local researchers quickly scramble to find the cure which is faded and illegible in the ancient tome that describes the illness.
50* The crew of the ''Anime/SpaceBattleshipYamato'' had a year to reach a planet on the other side of the galaxy, get a device that would decontaminate an otherwise radiation-poisoned Earth, and get back to use it, before Earth became permanently uninhabitable.
51* ''Anime/ZoidsChaoticCentury'':
52** Happens after RobotBuddy Zeke is fatally injured in a battle against TheDragon Raven and IdiotHero Van must travel to a volcano to find [[MacGuffin a rare mineral called Zoid Magnite]] to revive Zeke.
53** [[RecycledScript Done again]] in "Genesis", where Ruuji must track down a rare flower to cure Rei Mii after she comes down with an illness.
54[[/folder]]
55
56[[folder:Comic Books]]
57* In ''Comicbook/AllSuperheroesMustDie'', Cutthroat is injected with 90s and goes through a frantic search for an antidote to avoid exploding.
58* ComicBook/DoctorStrange occasionally needs to find a magical cure for an ailment that is beyond modern medicine. ''The Oath'' and ''Spider-Man: Fever'' both involve his attempts to save the lives of Wong and Spider-Man, respectively.
59* Used in ''ComicBook/ElfQuest'' when Skywise has to find some Whistling Leaves (a diuretic) to help cure Cutter's fever. He only finds the leaves in the end due to a small breeze, which causes the leaves to give out the whistling sound they were named for thus, guiding him to the plant.
60* Used on ComicBook/SpiderMan by the Hobgoblin back in the late eighties or early nineties. The Hobgoblin [[WhyDontYouJustShootHim doesn't just shoot him]] because [[JustifiedTrope he wants Spidey to give him the Green Goblin's journals]]. Played with, in that the Hobgoblin doesn't have the antidote -- but Spidey gets it from the Kingpin in exchange for help dealing with Hobgoblin (who is a rogue element in Fisk's plans).
61* The ComicBook/TeenTitans ask for ComicBook/{{Robin}}'s help when ComicBook/{{Superboy}} is dying from his first run-in with a deranged Superboy Prime and Robin quickly surmises that Lex Luthor will have a cure for what's killing Kon. Tim leads them to break into and search one of Luthor's secret hidden labs, where they do indeed find the cure as well as some... less pleasant things.
62[[/folder]]
63
64[[folder:Fan Works]]
65* ''Fanfic/CorEtCerebrum'': Bruce comes back from a trip in space suffering from some kind of bizarre hallucinogenic poison which Dev has to work quickly to try and treat, but also has to suss out the nature of so that he can treat more than the pain.
66* ''Fanfic/FFSIBelieveInYou'': A large part of the sequel's story is the characters' attempt to find the recipe for a potion with which to heal Jabu Orkú, track down the ingredients, and deliver the finished cure to Zola Province and the ailing Jabu.
67* ''Fanfic/ItsADangerousBusinessGoingOutYourDoor'': Finding a cure for Twilight Sparkle is the central plot of the story, and requires the other characters to trek over two mountain ranges and two foreign countries to recover a very specific FlowerFromTheMountaintop.
68* In ''Fanfic/IWarrior'', it turns out that the reason [[BigBad the Master]] is after [[spoiler: [[ArtifactOfDoom Palpatine's holocron]]]] is because he believes it can cure him of the illness [[BodyHorror ravaging his body]]. [[spoiler: He's right, unfortunately.]]
69* In the ''Franchise/StarWars'' fic ''[[http://www.fanfiction.net/s/10660640/1/ Not Without You By My Side]]'', Leia is bitten by a tropical insect during an off-world visit. There's only one rare strain of bacta the infection responds to, so Luke and Lando Calrissian have to make a trip to Coruscant's shady lower levels to get the stuff from one of Han's smuggler buddies.
70* Played five times in the ''DarthWiki/WALLEForumRoleplay''. Thrice by Buddy, first by attempting to kill Auto (and as many other robots as would likely be infected, since they were expendable to his cause) and then by {{blackmail}}ing the Colony to Auto scrapped; once by Blacklight, who wanted to wipe mankind off Earth to rescue the robots; and once when the remains of the Black Plague virus actually became [[TheVirus sentient.]]
71* In ''Series/StarTrekTheOriginalSeries'' fanfic [[https://archiveofourown.org/works/27084541/chapters/66133225 Something Wicked This Way Comes]], this is what sets the plot in motion as the few healthy members of a starship crew use a poorly understood piece of alien technology in desperation to get the antidote needed to cure their comrades in time. [[spoiler: It doesn't work - the ship ends up trapped in an alternate universe, and reappears a decade later, triggering the main plot as the ''Enterprise'' is called to investigate.]]
72* In ''Fanfic/AnotherTimeAnotherPlaceAnotherStory'', Liu Qingge refuses to let Shen Yuan's chronic bad health cause his premature demise and starts to explore the cultivation world because it has treatments to achieve immortality. It's later revealed that Shen Yuan's father attempted the same quest only to fail, and is currently hoping for Liu Qingge to succeed in his stead.
73* ''Fanfic/DanceWithTheDemons'': Catwoman has been injected with an unidentified poison, prompting Batman and his allies to look for the culprit to find the antidote.
74[[/folder]]
75
76[[folder:Films -- Animation]]
77* The first ''WesternAnimation/{{Balto}}'' movie. In this case, everyone knows approximately where the diphtheria antitoxin ''is'' -but they have to get it to Nome [[ProductDeliveryOrdeal in severe weather conditions and precarious snowy terrain]] that only allow sled dogs and their white and native Alaskan handlers to travel. Planes are out.
78* Franchise/{{Barbie}} [[WesternAnimation/{{Barbie}} movies]]:
79** In ''WesternAnimation/BarbieMariposa'', Mariposa, Rayna, and Rayla journey to find an antidote for the poisoned Queen, Marabella.
80** In ''WesternAnimation/BarbieThePearlPrincess'', after Scylla is poisoned, they must find the antidote.
81* In ''WesternAnimation/TheLandBeforeTimeIVJourneyThroughTheMists'', Grandpa Longneck is stricken with an unspecified illness, requiring Littlefoot and his friends to track down a specific type of flower that contains a cure.
82* Pretty much the whole plot of ''WesternAnimation/OnceUponAForest''. A little badger named Michelle becomes comatose after inhaling toxic gas that killed all the local herbs, so her three older friends must travel beyond the forest to find the herbs she needs to be cured.
83[[/folder]]
84
85[[folder:Films -- Live-Action]]
86* ''Film/Blade1998'': After Karen discovers [[spoiler:she's been infected with vampirism]], she sets about using her medical knowledge to find a cure. She discovers a retrovirus that can turn vampires back into humans and she successfully uses it on [[spoiler:herself]], although she speculates it will only work for vampires who were once human and not for Purebloods due to the vampire virus being genetically fixed into them.
87* In ''Film/IndianaJonesAndTheLastCrusade'', Donovan shoots Indiana's father, mortally wounding him. If Indiana can't get past three deadly traps, find the Grail, and return with it in time, his father will die.
88* The plot of the BasedOnATrueStory ''Film/LorenzosOil''. The Odones search desperately for a cure, or at least treatment, for their son's ALD (adrenoleukodystrophy). Sponsoring an international symposium of scientists, they follow a thin lead to an oil with two specific long-chain fatty acids. This reduces the problem that's causing the disease, but then they learn a case as advanced as their son's also requires replacing or regenerating the nerve myelin sheaths. So they start working on that. Meanwhile, the oil is used on many patients to arrest the progress of their ALD, preventing the damage that harmed the Odones boy.
89* ''Film/TheNeverendingStory'': Atreyu's quest, in essence, since doing so for the Empress will also save Fantasia from The Nothing.
90* The premise of ''Film/SawII''. Eight people in a cellar have been poisoned and have two hours (ie most of the movie) to try to retrieve doses of antidote from the various death traps.
91* ''Film/TwiceToldTales'': In "Rappaccini's Daughter", Giovanni goes to his chemistry professor in the hopes of finding a cure after Rappaccini turns him into a PoisonousPerson.
92* ''Film/VanHelsing'': After discovering that [[spoiler:her brother Velkan]] has become a werewolf, Anna mentions that Dracula is rumored to have a cure for lycanthropy, although Van Helsing dismisses it as a pipe dream, and it becomes a moot point once the werewolf curse fully takes over [[spoiler:Velkan]] after the final stroke of midnight on his first full moon. Later, [[spoiler:Van Helsing is infected himself, and he and his allies discover that Dracula's werewolf cure is real, prompting Anna and Carl to race against time in order to retrieve the cure and administer it to Van Helsing before he shares Velkan's fate]].
93[[/folder]]
94
95[[folder:Literature]]
96* In ''Literature/ArtemisFowl: The Time Paradox'', the only cure for Angeline Fowl's disease is the brain fluid of the silky sifaka lemur, except silky sifakas went extinct eight years ago. Artemis himself made sure of that.
97* Biblical Apocrypha has the ''[[OlderThanFeudalism Book of Tobit]]'', where a young man named Tobias must go search for a cure for his blind dad Tobit. His travel companion happens to be the Archangel Raphael in disguise, and while Tobias searches for both Tobit's cure ''and'' falls for a girl named Sarah, Raphael fights a demon that [[CartwrightCurse keeps killing every man poor Sarah has married]] before getting together with Tobias.
98* ''Literature/BridgeOfBirds'': The plot of the novel -- at least until the parallel plot comes to light.
99* Often appears as part of the mindgames played by ''Literature/ButlerParker''. You got hit with a blowgun dart? The nice old man tells you to consider your chances should the dart be poisoned? He even has a cure, but wants to get some information from you first? If you give in and tell him what he wants to know, he'll probably give you a 'cure' - an antacid or a breath mint. And yes, the dart probably ''was'' poisoned after all - with a slow-acting sleeping poison, and once you wake up again, you'll be none the worse for wear...
100%% * ''Literature/DeepwaterBlack'' was based on this premise.
101* ''Literature/TheDiamondThrone'' centers on a search for the only thing that can cure the poison that the Queen has been poisoned with. In the villain's defense, he had to make it look natural, so instantly lethal means was out of the question, and he could not have anticipated either the magic that kept her alive long enough for the cure to be found or that there actually ''was'' a cure that could be found.
102* In ''Literature/EmpireOfIvory'', once [[spoiler: Temeraire]] proves immune to the IncurableCoughOfDeath that is killing [[spoiler: the rest of Britain's dragons,]] there is a scramble to Cape Colony in the hops of finding what cured him of the cold that it was initially dismissed as. [[spoiler: Too bad a cave full of the mushrooms in question happened to be under cultivation by a [[HiddenElfVillage Hidden Dragon Empire]].]]
103* In Ryan Graff's ''Literature/TheFiresOfAffliction'', the MysteryCult repeatedly poisons, then cures, the heroine Lori as a way of preventing her from escaping their grasp. When she finally breaks out and meets the hero, he scrambles for another way to cure her.
104* The villain of ''Literature/GalaxyOfFear: The Planet Plague'' didn't know of a cure and just wanted Tash to [[spoiler: [[TheVirus transform into a]] BlobMonster]]. But he got this virus from the ruins of an old civilization and said civilization also wrote down how it could be cured. The heroes were fortunate not only to find that but to have a droid find it so it could be recorded.
105* ''Literature/TheGoldenHamsterSaga'': In ''Freddy's Final Quest'', Signor Goldoni's son has an incurable genetic blood disorder that will soon kill him. Goldoni thinks that if he could get some of the family's DNA from before the disorder appeared in their bloodline, he would be able to develop a cure. He invents a time machine and sends Freddy, Sir William, Enrico, and Caruso back to twelfth century Assyria, where his ancestor Cavaliere Goldoni was a crusader, to try to collect a DNA sample.
106* Creator/JulietMarillier's ''Literature/HeartsBlood'': After [[spoiler: Anluan]] is poisoned, Caitrin must find the antidote and brew it without knowing what kind of poison it is or where the antidote is written, all in less than an hour.
107* Used twice in ''Literature/TheLordOfTheRings'' with the Athelas plant (also known as Kingsfoil) which it seems only Aragorn knows how to use as more than a simple headache remedy. The first time, he uses it to help relieve the pain of Frodo's wound from a Morgul-knife and the second time to cure those who have been afflicted by "The Black Breath", spread by the Nazgûl. Both times, the plant has to be sought out since there is none at hand when it's needed.
108* During ''Literature/TheMalloreon'' Zakath is given a poison that has no known antidote. Her search is relatively short, only a chapter, as they consult Cyradis who tells them the only cure is the panacea, quickly identified as Adara's rose.
109* The second book of ''Literature/TheMerlinSaga'', ''The Seven Songs,'' has Merlin's mother Elen stricken by a slowly-killing death curse, forcing Merlin and his friends to embark on a long, Labors of Hercules-style mission to find the Elixir of Dagda, the only cure.
110* Happens at least once in ''Literature/{{Redwall}}''. In ''Salamandastron'', a FlowerFromTheMountaintop is needed to create medicine which will cure a plague.
111* ''Literature/TheRiftwarCycle'' novel ''Silverthorn'' has this as the major plot, when the protagonist must quest for the plant of the title in order to cure a princess who was struck down with a poison made from the very same plant.
112* Doubly subverted in ''Literature/SeptimusHeap: Physik'': Queen Etheldredda is actually trying to lure Septimus into a trap so she can extort Jenna to bring him to a place where he is kidnapped into a time 500 years ago, but there he does find the cure for the Sickenesse that is ravaging the Castle in the present time.
113* ''Literature/ASeriesOfUnfortunateEvents'': In "The Grim Grotto", Sunny is infected by a deadly mushroom called the Medusoid Mycelium, forcing Klaus and Violet to find a cure. They find that horseradish is the cure, but since that is not available on the submarine they are in, they use Wasabi as a substitute.
114* ''Literature/TheTwoPrincessesOfBamarre''
115** The whole point of ''Literature/TheTwoPrincessesOfBamarre'', with the added twist that Addie's not sure if the cure's even real, [[spoiler: and when they do find it, it's too late for Meryl, who has to have an EmergencyTransformation]].
116** Also played with, in that [[spoiler:while the cure that Addie ultimately found would have worked just fine, she also inadvertently found the "real" cure, which everyone in the kingdom had been searching for -- by being a "coward who found courage", Addie caused rain to fall all over the land. The rain came from the home of the fairies and cured everyone of the disease.]]
117* A large portion of the ''Literature/WarriorCats'' novel ''Long Shadows'' deals with Jayfeather trying to find catnip to cure a recent epidemic in his clan after his stock was destroyed.
118[[/folder]]
119
120[[folder:Live-Action TV]]
121* In the ''Series/{{Alias}}'' episode "Counteragent," Sydney needs an antidote to a virus that is killing Vaughn. Sark says she can have it if she brings him Sloane.
122* Thoroughly subverted by the ''Series/BabylonFive'' episode "Confessions and Lamentations", in which Doctor Franklin spends the entire episode searching for a cure while Delenn tends the plague-stricken Markab people, and the rest of the cast deals with other consequences of the plague. In the end, Franklin races to the quarantine ward with the cure... only to discover a tearful Delenn, who informs him that he's too late: they've all died. He is in time, at least, to prevent the disease from spreading among the pak'ma'ra, who are also vulnerable.
123* Part of the SickEpisode slash ContaminationSituation episode "The Pathos in the Pathogen" on ''{{Series/Bones}}''. Arastoo is accidentally infected by a modified virus while processing the victim. The standard issue serum for the disease fails and Booth has to find the killer since the lab group reasons the killer would have an antidote in case he got sick. Turns into WithholdingTheCure briefly until Brennan forces the guy to give it up.
124* An example of the second approach occurs in the third season finale of ''Series/BuffyTheVampireSlayer'', "Graduation Day". Faith shoots Angel with a poisoned arrow; she could easily have hit his heart and dusted him, but she and the Mayor would rather Buffy stay distracted by his illness and eventual, slow, and painful death. Of course, this backfires on Faith when the antidote turns out to be Slayer blood...
125%% * Basically every episode of ''Series/TheBurningZone''.
126* One episode of ''Series/{{Castle|2009}}'' hit Castle with a poison that led to this, but justified: the villain didn't even know Castle existed, let alone that he'd been hit with the poison. The actual target of the poison ''was'' killed almost immediately by it, Castle just got a low dose of it accidentally (enough to kill him, just not as immediately) by being in the same car with the victim for a few minutes.
127* ''Series/{{Chuck}}'' has this in the Season 4 finale when [[spoiler: Sarah is poisoned by Vivian Volkoff on the eve of their wedding and Chuck has to find a cure.]]
128* The ''B5'' SpinOff series ''Series/{{Crusade}}'' was entirely premised on this: the cast was searching for a cure to a plague visited upon Earth by former Shadow minions, which would conveniently lie dormant for five years before killing everyone. (The plan was to set up an audience expectation that the cure would be found in the fifth and final season, then have the cure discovered somewhere around Season 3 and spend the rest of the series fighting a new and greater danger uncovered during the search. All this was rendered moot when the series was canceled before even airing.)
129* ''Series/DoctorWho''
130** In "The Caves of Androzani", the Fifth Doctor is forced to regenerate after he and his companion Peri are poisoned -- although he manages to milk the giant Queen-Bat to get the antidote (don't ask), there's only enough for one.
131** Much of "The Green Death" is devoted to finding the eponymous infection. The ImprobableAntidote turns out to be the dried spores of the fungus Professor Jones was working on.
132* Happens twice to Aeryn in ''Series/{{Farscape}}'': first when she needs a tissue transplant in Season 1 so the team has to infiltrate a Peacekeeper base and again in Season 4 when she is infected with the "Living Death" by an enemy who possesses the only cure.
133* An ongoing theme in ''Series/ForeverKnight'' is coroner Natalie Lambert trying to find a cure for VampireDetective Nick Knight. As vampirism is symbolically compared to alcoholism, she often complains that Nick isn't putting in the effort that he should, despite his desire for redemption.
134* In one episode of ''Series/FoylesWar'', one woman dies of a mysterious illness and Sam comes down with the same symptoms, becoming gravely ill. Foyle's investigation leads him to an Army research post where they are trying to cultivate anthrax as a bioweapon; sloppy handling led to the two civilian infections. Foyle threatens to return with more police, more officials, and worst of all the ''press'' unless they give him a cure. They hand him a bottle of streptomycin antibiotic, but (as is TruthInTelevision) warn him that it isn't a ''guarantee'', just that it will probably help. (Fortunately for Sam, it does.)
135* ''Series/GameOfThrones'': After she learns of his greyscale infection, Daenerys orders Jorah to find the cure and return to her. He gets his wish after being treated by Samwell Tarly at the Citadel.
136* This is an important part of the plot in ''Series/TheJulekalender''. Gammel Nok is dying because the music box that plays the melody of his life is about to stop. The main characters Fritz, Hansi, and Günther have to look for the only key that can wind up this music box.
137%% * ''Series/{{MacGyver|1985}}'' did this at least ''twice''.
138* In ''Series/{{Merlin|2008}}'', Arthur goes on one of these after Merlin takes a poisoned chalice originally meant for him.
139* ''Series/TheNewAvengers'': In "Target!", Purdey and Steed are poisoned and Gambit has to race to find the antidote: which the villain has hidden in the center of the agency's ShootingGallery. The automaton targets have been modified to shoot poisoned bullets, and the victims die days afterwards so there's no link between the two (until our heroes investigate, of course).
140* In the ''Series/{{Nikita}}'' episode "Phoenix", Nikita is injected with an exotic poison in order to force her to assist the Russian private intelligence agency Gogol with the assassination of a U.S. Senator. Unbeknownst to Gogol, however, Nikita's partner Alex has infiltrated the organization Gogol copied the poison from in the first place, and thus has access to its antidote.
141* ''Series/StarskyAndHutch'': In the episode "A Coffin for Starsky", Starsky is injected with a poison that will kill him in 24 hours; in this case what they need to find is a sample of the poison so the cure can be created. A less personalized version occurs in "[[ExactlyWhatItSaysOnTheTin The Plague]]", in which Hutch is one of the first victims of an incipient epidemic, and Starsky has to track down a hitman with a natural immunity to the disease.
142* ''Series/XenaWarriorPrincess'': Season 3, Episode 13, "One Against an Army".
143* ''Franchise/StarTrek'':
144** In ''Series/StarTrekDeepSpaceNine'', Section 31 creates a disease designed to annihilate the Founders in order to bring down the Dominion and end the war. In order to transmit the disease to the Founders, they use Odo as a carrier. This leads to three episodes of this for Dr. Bashir, with "Extreme Measures" being the embodiment of this trope.
145** Subverted in "The Quickening." Bashir comes to the aid of a planet that was infected with a plague two centuries ago by the Jem'Hadar, expecting to swoop in with his genius and his gadgets and save the day with another miracle of 24th-century Starfleet medicine. It doesn't work out that way. It turns out the disease was designed to accelerate when exposed to electromagnetic fields such as produced by modern medical equipment, which leaves a wave of patients in mortal agony pleading for euthanasia. However, Bashir was able to accidentally create an in-vitro vaccine to enable babies to be born free of the plague. Although the planet's population and Commander Sisko tell Dr. Bashir that this was a great accomplishment, he is hardly satisfied.
146* In the episode "Poison Ivy" of the 1991 series ''Series/TropicalHeat'', private investigator Nick Slaughter is poisoned and spends the rest of the episode trying to get his hands on the cure.
147* On ''Series/TheXFiles'', Mulder desperately searching for a cure for Scully's cancer makes up the episodes of "Redux" and "Redux II." [[spoiler: He does.]]
148* ''Series/{{Supernatural}}'': Loves this trope.
149** In Season 4, Dean is infected with ghost sickness which makes the normally brave and heroic Dean afraid of everything. Bobby and Sam have to work to find a cure.
150** In Season 6, Dean is infected with vampire blood, which will turn him into a vampire if he feeds. He eventually manages to find a cure before that happens.
151** In Season 7, Sam is being driven mad by his memories of Hell, and Dean desperately searches for a cure. He seeks out a faith healer [[spoiler: who turns out to be an amnesiac Castiel who eventually absorbs Sam's memories into his own mind.]]
152** A long arc through Seasons 9 and 10 involved Dean having the Mark of Cain, which turns him demonic, and the heroes desperately searching for a cure.
153* ''Series/TheYoungOnes'': During their SickEpisode, Neil hopes that Mike is able to find Music/{{the cure|Band}}. Vyvyan points out that they've got {{Music/Madness|Band}} [[{{Pun}} this week]].
154* In one episode of the live-action ''Series/{{Zorro|1957}}'', Zorro is poisoned by the villain of the week. He later tricks the villain into thinking that Zorro had poisoned him back with the same toxin, making him go to the nearest source of an antidote, which Zorro follows him to.
155[[/folder]]
156
157[[folder:Music]]
158* Music/{{Metallica}}'s "Cure".
159* This is the plot of the FilkSong [[https://www.youtube.com/watch?v=aqGv2l5bJr4 ''Witch of the Westmoreland'']]: a knight is badly wounded in battle and must seek the aid of the titular witch.
160[[/folder]]
161
162[[folder:Roleplay]]
163* In ''Roleplay/TheGamersAlliance'', the elven archer Rhylian is desperately searching for a cure to the Blood Fever, a disease that is fatal to elves.
164* In the Adventure Game included with ''Literature/WarriorCats'' ''The Fourth Apprentice'', the Clans are coming down with a sickness, so they send out the Adventure Game cats to find some herbs for them.
165[[/folder]]
166
167[[folder:Toys]]
168* ''Toys/{{Bionicle}}'':
169** A major portion falls under this (specifically the arc called ''Bionicle Legends''): two parts were dedicated to finding the MacGuffin that could save Mata Nui's life, and the third revolved around restoring him to consciousness.
170** There was also a smaller-scale one in the book "Maze of Shadows", where the plant monster Karzahni forces the Toa Metru to get him a flask of energized protodermis in exchange for curing Nokama of poison -- and to prove he could do it, he gave her a temporary antidote. It turned out that Karzahni needed to Find The Cure for a condition of its own, but too bad protodermis has UnpredictableResults.
171[[/folder]]
172
173[[folder:Video Games]]
174* In ''VideoGame/ANNOMutationem'', Ann's younger brother, Ryan, goes missing when he picked up a lead on finding [=N540=], a unique medicine that he wants to find which would cure Ann's [[SomethingItis Entanglelitis]]. [[spoiler:Even though Ryan succeeds in finding it at The Consortium's base, he was immediately captured when it turns out it was a trap to lure Ann in]].
175* A major plotline in ''VideoGame/BatmanArkhamCity'' has Batman seeking to find a cure to the disease killing ComicBook/TheJoker because [[spoiler:he gave Batman a blood transfusion as well as "donating" his blood to various hospitals in Gotham to ensure Batman's cooperation]].
176* In ''VideoGame/BeyondTheBeyond'', the party's strongman hero Samson is cursed by one of the {{Big Bad}}s early on in the game. The curse is so powerful that it [[GameplayAndStoryIntegration can't be lifted by normal priests]], leading the heroes to seek out God Himself to undo it.
177* In ''VideoGame/BlasterMasterZeroII'', [[spoiler:Eve]] is infected by mutant cells and Jason and Eve must travel to the planet Sophia to find a cure. [[spoiler:It's ultimately subverted, as Eve ends up curing herself prior to the TrueFinalBoss.]]
178* In ''Franchise/BlazBlue'', the ultimate goal of Litchi Faye-Ling is to find a cure that will not just restore her friend Lotte Carmine from [[EldritchAbomination Arakune]] to normal, but also a cure for herself about her encroaching corruption. Unfortunately, the one she knew could help her, Kokonoe, flat out refused, and [[ObviouslyEvil Hazama]] claims that NOL has the cure. Litchi [[spoiler:was quick enough to realize that it's {{Blackmail}} and Hazama is a very ominous, suspicious dude, but with her time to get completely corrupted drawing ever nearer, she ends up ForcedIntoEvil to preserve the cure.]] By ''VideoGame/BlazBlueCentralFiction'', she ''actually'' managed to procure one cure that's guaranteed to be safe to use. [[spoiler:Unfortunately, when she managed to confront Lotte about it, he just stated that he actually knew that cure already, and was deliberately not using that cure to stay the way he is, as he has chosen to stay that way. This pretty much rendered everything Litchi did AllForNothing.]]
179* In ''Videogame/{{Bloodborne}}'', the Hunter suffers from an unknown disease. So they journey to the city of Yharnam, the home of blood ministration, in order to seek [[{{Panacea}} Paleblood]]. Creator/FromSoftware seems to like this trope.
180* In ''VideoGame/BloodOmenLegacyOfKain'', Kain's initial motive for going after the Circle of Nine is a cure for his vampirism... though he [[TranshumanTreachery slowly begins to embrace it]]. [[spoiler:It turns out however there is no "cure" in the conventional sense. Unknown to Kain until the very end, he is in fact the new corrupted Guardian of Balance, born between the time of the previous Guardian Ariel's death and the Pillar's subsequent corruption, and so killing the other Pillars won't save Nosgoth as long as he's still alive. [[TreacherousQuestGiver Ariel's spirit]] deliberately withheld this information in the hopes that Kain would ultimately willing choose to sacrifice himself in the end. As it turns out, he was rather miffed at this manipulation and it served as the final straw for him ''refusing'' to sacrifice himself and fully embracing his vampire state.]]
181* ''VideoGame/ChronoCross'': Early on, Kid is poisoned by Hydra Venom, which requires Hydra ''Humor'' to cure. Problem being, the hydras are extinct in this dimension. You can choose not to fetch it--she'll be cured by a strange from the mainland anyway [[spoiler:Norris]] and not commit an act of ecological vandalism, but it mostly depends on which characters you want to join you.
182* ''VideoGame/DarkSouls'': The Chosen Undead is suggested to be searching for a cure for their Undeath [[spoiler:and discovered that there was no cure for the Undead Curse. Their only options are to become kindling for the First Flame or let it die and try their hand at ruling a world of Dark.]]
183* In ''Videogame/DarkSoulsII'', the Bearer of the Curse is lured to Drangleic by rumors of a possible cure to the Undead Curse. [[spoiler:There is no cure. The rumors were merely the Emerald Herald's bait to bring Undead to Drangleic in hopes of finding someone capable of ending Nashandra and Linking the Fire.]] At the end of the ''Lost Crowns'' DLC trilogy, [[spoiler:King Vendrick will bestow a blessing upon all of the crowns that prevents Hollowing as long as they are worn. It's not a cure, [[CursedWithAwesome but it does remove the only harmful part of the Curse]].]]
184* ''VideoGame/DiceAndTheTowerOfTheReanimatorGloriousPrincess'': Bambooblade's goal is to find the elixir that can cure Princess Gloria's disease, but the Reanimator has this item and isn't willing to share.
185* The main plot of ''Videogame/TheDogIsland'' is this. The player must travel to The Dog Island to search for a cure for a mysterious and rare sickness that has infected their younger sibling, the cure itself being the Legendary Flower.
186* ''VideoGame/DragonAgeInquisition'': The Hero of Ferelden is now on a quest to find a cure for the Blight: a [[MysticalPlague magical disease]] infecting all Grey Wardens that is lethal to all life. The Blight is believed to be [[ThereIsNoCure impossible to cure]], but the Hero has dedicated themselves to proving them wrong and saving all who are infected regardless of what it takes. While most consider this goal to be a pipe dream, those who know the Hero of Ferelden personally have faith that they'll defy the odds and succeed somehow.
187* ''VideoGame/EasternExorcist'' have this as the main plotline of Xiahou-xue's quest; her brother, Xiahou-qing, sacrifices himself to save her from being poisoned by a Snake Yaksha, and only survives by having his soul escaping his physical body, now uninhabitable because of the venom. Xiahou-qing can still survive in spirit form, but only for six months; players as Xiahou-xue must go on a quest to seek an antidote and restore her brother's body before it's too late.
188* ''Franchise/TheElderScrolls''
189** While it is widely believed throughout Tamriel that there is no cure for [[OurVampiresAreDifferent Vampirism]], there are recorded cases of individuals being cured. Knowledge of how to be cured is typically suppressed for two major reasons: One, because the cure is often extremely unsavory. Two, in order to discourage [[VampireVannabe wannabe Vampires]] from intentionally infecting themselves with the disease. In each game where the PlayerCharacter can contract the disease, the cure does indeed prove to be rather unsavory. To note:
190*** In ''[[VideoGame/TheElderScrollsIIDaggerfall Daggerfall]]'', curing the Iliac Bay strain of vampirism requires killing the "Bloodfather" of that particular vampire bloodline. Doing so cures the entire clan, however, it does so in the NoOntologicalInertia sense. Because of the disease's [[TheAgeless agelessness]] property, it causes rapid aging in the newly cured. Any vampires which have already exceeded the lifespan of their race suffer RapidAging and die.
191*** In ''[[VideoGame/TheElderScrollsIIIMorrowind Morrowind]]'', getting cured requires currying favor with [[GodOfEvil Molag Bal]], [[OurGodsAreDifferent Daedric Prince]] of [[NamesToRunAwayFromReallyFast Domination and Corruption]], who is also the "[[MonsterProgenitor Father]]" of all vampires. Given that Molag Bal is one of the few Daedric Princes considered unanimously evil and is one of the "Four Corners of the House of Troubles" to Morrowind's [[CorruptChurch Tribunal Temple]], it's easy to see why the Temple censors any rumors of a cure to vampirism and considers the only "cure" to be a swift MercyKill.
192*** In ''[[VideoGame/TheElderScrollsIVOblivion Oblivion]]'', you must commune with a witch in order to be cured. She requires ingredients for a potion that includes the blood of an [[LizardFolk Argonian]]. (You don't need to actually ''kill'' the Argonian, but most of them don't take kindly to being stabbed by a special dagger to draw blood.)
193*** In ''[[VideoGame/TheElderScrollsVSkyrim Skyrim]]'', getting cured requires working with a Conjurer who will cure you in exchange for a filled Black Soul Gem. "Black" souls are those of sapient beings, and the ''Dawnguard'' DLC reveals that sapient beings who have been soul trapped are doomed to spend eternity in the bleak Soul Cairn. Essentially, you are dooming someone to a FateWorseThanDeath to cure yourself of the disease. Alternatively, if you are a member of the [[AdventureGuild Companions]], you can choose to [[spoiler:become infected with Lycanthropy, which clears the Vampirism]]. That may or may not be considered better depending on the circumstances.
194*** ''[[VideoGame/TheElderScrollsOnline Online]]'' offers by far the easiest means of being cured. You simply need to pay a Mages Guild healer to cure you instantly.
195** This is likewise the case throughout the series for curing [[OurWerebeastsAreDifferent curing Lycanthropy]]. For similar reasons to the cure for Vampirism, knowledge of the cure for Lycanthropy is likewise suppressed.
196** In ''Morrowind'', part way through the main quest, [[spoiler:one of the BigBad's minions will infect the PlayerCharacter with the Corprus Disease, a divine disease created with the power of the [[GodIsDead heart of a dead god]]]]. Corprus comes with a nasty case of BodyHorror and decreasing mental faculties. Divayth Fyr, the [[ReallySevenHundredYearsOld 4000-year-old]] wizard is known to be working on a cure, so the PC must seek him out. [[spoiler:Ultimately, he [[SubvertedTrope Subverts]] the trope. He does cure the negative aspects of the disease, but not the disease itself. Thus, the PC is left with the positive aspects of being TheAgeless and having IdealIllnessImmunity]].
197* ''VideoGame/FateGrandOrder'': While preparing to invade the Atlantic Lostbelt, the protagonist and Goredolf eat half a poisoned cake each, and the assassin who sent the cake made the poison from ingredients not found in Proper Human History. Said ingredients are traced to the Chinese Lostbelt, forcing Chaldea to forego Atlantis for now and search for a cure in the alternate China.
198* ''Franchise/FinalFantasy'' has several examples:
199** In ''VideoGame/FinalFantasyIV'', Rosa comes down with a sickness that can only be cured by the secretions of a rare desert arthropod. This happens to another character in ''[[VideoGame/FinalFantasyIVTheAfterYears The After Years]]''.
200** Inverted in ''VideoGame/FinalFantasyV'', as in a flashback you learn that a mother of a character had a disease that could only be cured by a dragon's tongue. However, since this would kill the dragon, the character decides not to do it. Played straight on the two occasions the heroes need to find dragon grass to cure sick wind drakes, however: it only grows, in small quantities, on certain remote mountaintops, and in one case has mutated into a monster.
201** Finding the cure for Crystal Sickness kicks off the plot in ''VideoGame/FinalFantasyCrystalChroniclesEchoesOfTime''.
202* In ''VideoGame/GemsOfWar'', the bulk of the Forest of Thorns quest-line involves Rowanne's attempts to find a cure to the corruption there. It also involves fighting off elves who think looking for a cure is a dead end. In the end, [[spoiler:the "cure" does stop Gloom Leaf... by killing him.]]
203* A villainous example occurs in ''VideoGame/Guacamelee2'': the BigBad, Salvador, is searching for the three relics that will lead him to the Sacred Guacamole in order to cure his IncurableCoughOfDeath (not that he'd ever admit to having one), which was brought about due to his body being unable to handle the power of his mask. And if the Mexiverse has to collapse on itself in the process, then so be it...
204* In ''VideoGame/HarvestMoonBackToNature'', Lillia's husband is [[TheGhost on a quest]] to find a cure for her SoapOperaDisease. He's looking for a flower that only grows once a decade in a desert.
205* In ''VideoGame/{{Heretic}} II'' the protagonist is infected with TheVirus at the beginning of the story and has to find the cure not only for other people but also for himself.
206* In ''VideoGame/HyperdimensionNeptunia'', Neptune gets poisoned by the Archbishop of Leanbox, leading Compa and IF to scramble to find seven herbs[[note]]a reference to an NES game called ''Kid Kool and the Quest for the Seven Wonder Herbs''[[/note]] needed to make the cure. Luckily for them, [[SurprisinglyEasyMiniQuest all of the herbs are contained in the same dungeon, and the enemies are much weaker than the ones the party has faced previously in the story.]]
207* The Drifter from ''VideoGame/HyperLightDrifter'' is seeking the Immortal Cell in order to cure his IncurableCoughOfDeath. He is not alone in his quest, either; a second drifter is searching for it as well and often shares info with the playable character. In the end [[spoiler:it turns out that the Incurable Cough actually ''is'' incurable; the Immortal Cell was never a cure, it was an ArtifactOfDoom, a false hope that The Drifter had to destroy.]]
208* Delsin and Regggie in ''VideoGame/InfamousSecondSon'' set out to find Brooke Augustine after she uses her powers to interrogate and torture their tribe, who will die if they cannot get her to reverse the effects. When she refuses Delsin decides that he must use his own PowerCopying abilities to take hers and heal them himself.
209* The Shimmer Cure plot in ''VideoGame/IWasATeenageExocolonist'' revolves around Sol exploring the Valley of Vertigo to help Tang and Instance find the cure for the disease to save those who got infected such as [[spoiler:Geranium.]]
210* The goal of ''VideoGame/{{Larn}}'' is to find a potion to cure your daughter's terminal illness.
211* ''Franchise/TheLegendOfZelda'':
212** ''VideoGame/ZeldaIITheAdventureOfLink'': An old woman in the town of Mido asks Link to find a medicine so she can cure her sick daughter. Link can find a bottle full of Water of Life in a cave north of Moruge Swamp (which in turn is in the opposide side of the mountain that surrounds Midoro Swamp), but its entrance is blocked by a boulder that can only be broken with the Hammer. Once Link enters the cave and grabs the bottle, he can deliver it to the old woman, who in return lets Link enter her house so he can learn a new spell from a sorcerer.
213** ''VideoGame/TheLegendOfZeldaBreathOfTheWild'': One side quest in the game has Link hunt down a Molduga and harvest its guts to cure a Gerudo's husband.
214** ''VideoGame/TheLegendOfZeldaTearsOfTheKingdom'': An old woman in Kakariko Village gets sick from touching [[MadeOfEvil Gloom]]. You have to cook a particular dish that heals [[MaximumHPReduction Gloom damage]] to cure her, which also teaches you how to cook such dishes for yourself.
215* The Dangi Corporation in the fan mod ''VideoGame/{{Marathon}}'' Rubicon develop a cure for a virus they made. It was used in a scheme to take over the galaxy by [[spoiler: infecting food from various companies which was sent to various planets]]. They offered the cure in exchange for governmental control. At least, this is what happens if you stay on Pfhor Prime.
216* ''VideoGame/MarioAndLuigi'':
217** In ''VideoGame/MarioAndLuigiSuperstarSaga'', Mario wins a game at an arcade and obtains a strange mushroom as the prize. He eats it and becomes inflicted with a disease called Bean Fever, which makes whoever has it slowly turn into a bean, and Luigi has to go to some ancient ruins to find Crabbie Grass, the only known cure.
218** In ''VideoGame/MarioAndLuigiBowsersInsideStory'' the several Toads of the Mushroom Kingdom get the Blorbs, which cause their bodies to swell until they are large and round. Midway through the game, a cure for the Blorbs is discovered, and Mario and Luigi have to gather the three Star Cures to make it.
219*** The remake of ''Bowser's Inside Story'' has a new side story called ''VideoGame/BowserJrsJourney'', where the Bowser's Goomba minions are revealed to also become victim of the Blorbs. Bowser Jr. gets a recipe for the cure (an alternative cure from the one the Mario Bros. gets) and goes out to get the ingredients. However, the villains of the mode sold the recipe to Bowser's minions so they could steal the completed cure, and mix it with another ingredient to make a powerful brainwashing drug.
220* This is the main objective in the Storyline of ''[[VideoGame/MitsumeteKnight Mitsumete Knight R: Daibouken Hen]]'': the King of the kingdom the main character serves, is gravely poisoned by a terrorist group, and the only way to cure him is a mysterious MacGuffin called "The Tear of the Star". It's so rare and legendary, nobody actually knows exactly what it looks like. And of course, the main character is sent on a quest to find it.
221* Justified in ''VideoGame/{{Penumbra}}: Black Plague'', as your foe [[TheAssimilator doesn't just want you dead]]...
222* ''VideoGame/PokemonScarletAndViolet'': The Path of Legends storyline, where you help Arven defeat the Titan Pokémon to find the Herba Mystica, is revealed to be a quest to find a miracle cure after defeating the second Titan Pokémon. [[spoiler:Arven shows you his ailing Mabosstiff, whose illness can't be cured by Pokémon Centers or Potions, and he aims to find all the Herba Mystica because they're the only medicine that can heal his Pokémon.]]
223* Several games in the ''Franchise/ResidentEvil'' franchise has you hunting down a cure for someone:
224** ''VideoGame/ResidentEvil1'', if you're playing as Jill, has you look for Serum to cure a wounded and poisoned Richard, but he dies whether you get the cure to him on time or not. Richard is already dead by the time Chris finds him. In the remake. If you get the cure to Richard quickly, he will be alive, but he pulls a HeroicSacrifice later on since he's DoomedByCanon.
225*** In the original game and the remake, if you get poisoned by the giant snake on your first encounter with it, your character slumps over from the poison, causing their partner character to show up and administer a cure.
226** ''VideoGame/ResidentEvil2'' for Claire's Scenario A has the character developing a vaccine that will stop the G-Virus embryo that was implanted in 10-year-old Sherry Birkin. [[spoiler: By ''VideoGame/ResidentEvil6'', the embryo within Sherry remains dormant due to the vaccine, but is not eliminated. Instead, Sherry's body adapts to the embryo and it grants her super healing.]]
227** ''VideoGame/ResidentEvil3Nemesis'' and [[VideoGame/ResidentEvil3Remake its remake]] has Jill getting infected with the T-Virus by Nemesis, which kicks off the quest for the cure by Carlos and he delivers the vaccine on time. [[spoiler: The vaccine would cause Jill's body to develop antibodies specifically against the T-Virus and would be an effective cure. Wesker in ''VideoGame/ResidentEvil5'' captures Jill and ues her antibodies against her by implanting a mind-controlling device on her chest.]]
228** ''VideoGame/ResidentEvil4'' has Leon and Ashley get implanted with the Las Plagas, which will mutate and take control of their bodies if not eliminated on time. Breaking the trend of using a vaccine, the game "cures" the two characters by having them using ''electrical shocks'' on each other to kill off the parasite within them.
229* ''VideoGame/SailorMoonAnotherStory'': At the end of the first chapter, Mamoru is hit by an enemy attack which leaves him in a coma; a good portion of the game plot concerns the Sailor Guardians searching the world for the Four Heavenly Kings' Light stones, which have the power to bring forth the Rose Crystal, which can cure him.
230* The [[spoiler:Xchagger]] Plague subplot in the third installment of ''VideoGame/StarControl''. The victims: The Harika/Yorn. The culprits: unsurprisingly, [[spoiler: The Crux]].
231* A side quest in ''VideoGame/TalesOfSymphonia'' has Raine falling ill from a (completely non-villain caused) disease and the party has to spread out to find the antidote, which turns out to be a rare plant that only grows on the top of a single mountain in the whole world.
232* ''VideoGame/TheWindRoad'': One of the sub-quests in the village sees you trying to find an antidote for your poisoned monk friend, but unfortunately it leads to a ChainOfDeals scenario requiring you to find the silver scales of a rare fish, obtain a slab of beef, cross a forest filled with wolves, and save a butcher's protege from bandits.
233* ''VideoGame/WorldsEndClub'': Prior to arriving in Osaka, Chuko was bitten by a mouse and soon comes down with a fever, with the Go-Getters searching around the city for medicine to treat her.
234[[/folder]]
235
236[[folder:Web Comics]]
237* The villain Black Sundae poisoned the city's ice cream supply, and ''Webcomic/LadySpectraAndSparky'' had to find him and retrieve the antidote before the city's children succumbed.
238* ''Webcomic/{{Messenger}}'': Eldora's tribe is stricken with a potentially deadly disease. One of the Tribe's elders sends Eldora to find a cure.
239* In ''WebComic/YokokasQuest'', Raya and Yfa have to find a mushroom which grows on the back of a frog, to make medicine for Yokoka.
240[[/folder]]
241
242[[folder:Western Animation]]
243* ''WesternAnimation/ActionLeagueNOW'': The episode "What's Eating The Flesh" has The Flesh being infected with a body-eating virus, a virus, basically that eats away at the victim's body until there's nothing left. The League tries to stay away from him until Bill finds the cure, which comes in the form of dishwashing detergent, but to no avail. Thankfully, Bill cured the League in time.
244* ''WesternAnimation/AladdinTheSeries'':
245** In "Mission: Imp-Possible", Nefir the imp poisons Aladdin with a sleeping drug in order to goad Genie into helping him find a valuable treasure, the Golden Silk of Panacea (which also happens to be the only cure for the drug).
246** There's also Iago stealing fancy bath oils intended for the Sultan and thus consuming a poison intended to kill the Sultan that slowly turns him to stone, limb by limb. So of course the others try to get the cure, and Iago just [[FaceHeelTurn betrays]] them by giving the BigBad the lamp in exchange for the cure. Fortunately on the way there he has [[HeelFaceTurn a change of heart]], get captured, gets Aladdin and the rest captured, gets called a traitor, and then gets saved by Genie who points out that Iago changed his mind at the last moment and is not to blame. [[WildCard Make up your mind, Iago!]]
247** When Genie gets a cold that gives him PowerIncontinence, Aladdin and Iago go in search of the Orb of Mackinaw, a cure-all for genies.
248* ''WesternAnimation/AvatarTheLastAirbender'': "[[Recap/AvatarTheLastAirbenderTheBlueSpirit The Blue Spirit]]", where Aang must find the cure for a fever his friend got during the last episode... which turns out to be a frozen frog you suck on. ''[[ContinuityNod Two seasons later]]'', his friends are still bitter about this.
249* In the ''WesternAnimation/ChalkZone'' movie, Rudy, Penny, and Snap have to find a cure for "Ballonemia", a disease transmitted by tiny bats that makes Zoners inflate until they explode. [[spoiler:A cure doesn't exist, though the adventure gives Rudy the opportunity to contain the bats. Sometime afterward, he draws a giant soda can and has all the infected Zoners drink from it, allowing them to expel all their excess gas by burping.]]
250* Several times in ''WesternAnimation/{{Chaotic}}'', the main characters have to find a cure for an illness afflicting a creature or a location.
251* Done to the extreme on ''WesternAnimation/CodeLyoko'' at the end of Season 1 when XANA infects Aelita with a computer virus, [[{{Synchronization}} linking her to him and the continued functioning of the Supercomputer]] to prevent the heroes from [[CutTheJuice cutting the juice]]. Hence leaving Jérémie searching for a way to reverse this throughout Season 2, The Cure happening to be [[spoiler:Aelita's memories of her former human life, stolen by XANA.]]
252* ''WesternAnimation/ConanTheAdventurer'' does this as an episode. The disease was to make Conan susceptible to the metal in his sword (and his allies' weapons). Ironically, the metal itself would prove to be the cure, although not before the BigBad was tricking the allies into giving him his weapons to get what turned out to be a non-existent cure, and sending out his minions to destroy a valuable relic (the cloth covering a certain person's body, meant to cure anything) that the allies had just taken, to make sure the BigBad's route was their only option.
253* The deadly Ecto-Acne from ''WesternAnimation/DannyPhantom'' has main hero Danny looking for the cure after [[BigBad Vlad]] poisoned his friends with the same dose. The big problem: Vlad has the illness, too. The forced poisoning was intended as blackmail (which works). Danny eventually finds the final formula (it's diet soda)... right after he traveled through time, subsequently ruined the present time period, leaving him to SetRightWhatOnceWentWrong.
254* The plot of first season episode of ''WesternAnimation/{{Ewoks}}'' "To Save Deej" as well as "Rainbow Bridge", the very first in the series of comics revolve over a character's life being in danger and other characters finding ingredients for an antidote.
255* ''WesternAnimation/TheFairlyOddParents'': In "Chicken Poofs", Poof is infected with Chicken Poofs and starts infecting everyone in Dimmsdale with the disease. It only gets worse when chicken-eating birds start hunting the chickens and they end up in the hands of a chicken restaurant owner. Fortunately, Dr. Studwell has the cure...which is stored in a large needle for injection. Poof is unsurprisingly frightened and ends up breaking the needle. As such, Wanda and Dr. Studwell have to travel to a temple to get a cure, which is a flower. However, it turns out that Dr. Studwell was simply getting the flower so that he could get a discount on the cure (which was actually sold at a fairy pharmacy). Also, Studwell was not planning on injecting Poof with a needle but was instead planning on giving him a drink to cure the disease.
256* ''WesternAnimation/{{Gargoyles}}'':
257** "Long Way to Morning" has a B-plot {{flashback}} where the Gargoyles had to recover the formula for the antidote to a poison made by an evil wizard who poisoned the prince of their castle.
258** Meanwhile, in the main plot of "Long Way to Morning", Demona ''thought'' she poisoned Elisa (but [[PocketProtector Elisa's hidden badge deflects the dart]]) and held the clan hostage for the antidote. Goliath plays along; if he didn't chase Demona, then she would have realized her attack on Elisa had failed.
259* ''Franchise/{{Ghostbusters}}'': ''WesternAnimation/TheRealGhostbusters'' and ''WesternAnimation/ExtremeGhostbusters'' conducted variations on this.
260** In the RGB episode "Doctor, Doctor," the guys come down with [[BodyHorror a terrible, unspecified illness]] after an incident at a chemical plant. [[spoiler: ''Slimer'' turns out to be the cure: the negatively-charged ''whatever'' that's covering the Ghostbusters is attracted to the little spud, and literally flies off their bodies when he comes around.]]
261** In the EGB episode "Darkness at Noon," the evil Achira spreads a disfiguring plague across New York City. Capturing her ends the sickness
262* In the ''WesternAnimation/HerculesTheAnimatedSeries'' episode "[[Recap/HerculesTheAnimatedSeriesS1E39HerculesAndTheBigLie Hercules and the Big Lie]]", Herc tells Icarus he has "Catastrophia" to get away from a geeky comic-scroll convention. The cure is in the backyard of a giant. Icarus goes after it anyway.
263* Apparently the whole reason the parents of the titular character in ''WesternAnimation/HeyArnold'' went missing. Not only do they have to traverse the South American jungle to collect the ingredients of the dreadful Sleeping Sickness, they also have to ''find'' the very elusive patients called the Green Eyed People. Note that they do this plot twice... the latter apparently not ending too well.
264* ''WesternAnimation/JackieChanAdventures'', episode 9, "The Rock". It makes some sense that the villain has the antidote in this case, as his plan is to force Jackie into helping him by only giving him the cure if he does what the villain wants.
265* In the ''Westernanimation/KimPossible'' episode "[[Recap/KimPossibleS2E22Blush Blush]]", Drakken doses Kim with a pollen that will make her disappear little by little as she gets embarrassed. Ron goes to find the pollen, which should cure Kim if she gets a second dose.
266* An episode of ''WesternAnimation/KungFuPandaLegendsOfAwesomeness'' has Tigress getting sick, leading to her friends trying to get a rare flower guarded by an evil scorpion pharmacist.
267* In ''WesternAnimation/LegionOfSuperHeroes2006'', Brainiac 5 goes hilariously off-the-wall bonkers and needs an ultra-rare ore from Timber Wolf's seriously-ultra-wild-and-dangerous home planet.
268* ''WesternAnimation/TheLionGuard''
269** In a Season 2 episode ("The Scorpion's Sting) Simba gets stung on the tail by a scorpion, on direct orders from Scar. Kion and the Lion Guard ([[MyFriendsAndZoidberg and Makini]]) have to find a certain volcanic ash that can cure the dying king, though the volcano where the ash is at is home to Scar' malevolent spirit, as well as Janja's hyenas, Kiburi's crocodiles and Reirei's jackals.
270** Season 3 starts with Kion getting poisoned by snake venom that will [[PoisonIsEvil corrupt him]] into becoming an evil lion like Scar (who also went through the same process) and the rest of the season is about the group traveling to the Tree of Life to get a cure for Kion, as well as healing Ono's sight.
271* One of the full-length ''Animation/TheLittleMole'' movies, the protagonist's friend the Mouse gets ill. Krtek asks [[TheOwlKnowingOne the old Owl]] for adviceand is tolt to find a plant called ''Matricaria Chamomilla.'' Since the name's so grandiose-sounding, Krtek pretty much circles [[WorldTour the entire world]], asking virtually anyone who seems knowledgeable about whether a particular plant is his sought after ''[[RunningGag "Chamomilla?"]]'' He is ultimately unsuccessful and returns home, disappointed and sobbing. The Old Owl realises what went wrong, comforts him, and points at a plain-looking flower on the meadow, translating its Latin name into Czech term. If you know Latin, you'll have already realised that ''Matricaria chamomilla'' is [[spoiler: the common wild chamomile]]. Naturally, Krtek is overjoyed (if a bit embarassed) by this discovery, and goes to use the flower in brewing some tea for Mouse, who recovers.
272* ''Franchise/MyLittlePony'':
273** ''WesternAnimation/MyLittlePonyAndFriends'': "The Golden Horseshoes". Said horseshoes are the {{MacGuffin}}s needed to save a Pony from being erased from existence, so... Just the ponies' luck the horseshoes were scattered to the four winds.
274** ''WesternAnimation/MyLittlePonyFriendshipIsMagic'': When Zecora is infected with swamp fever, a disease with no known cure that slowly causes victims to permanently turn into trees, Fluttershy goes on a quest to find the journals of a legendary healer who may have known how to cure it. The cure turns out to be the honey of flash bees, who are able to harvest from the trees that spread the disease without being affected by it. Flash bees are extremely aggressive however so the only way to collect their honey is to wear a special flash bee mask.
275* ''WesternAnimation/SouthPark'':
276** The ''WesternAnimation/SouthPark'' episode "Red Man's Greed", the Native Americans gave SARS to the town using infected blankets to try to get rid of the townspeople to build a highway to their casino. Stan, who wasn't sick, went to search for a cure, which turned out to be Campbell's chicken noodle soup, [=DayQuil=], and Sprite.
277** In "Tonsil Trouble", Cartman accidentally gets HIV from a blood transfusion following his tonsil removal and deliberately infects Kyle after being mocked by him. The two of them set out to meet Magic Johnson[[note]]Cartman believes Magic can help them since Magic has lived for years despite having HIV[[/note]] to find a cure, which turns out to be [[spoiler:"about $180,000 shot directly into the bloodstream".]]
278* ''WesternAnimation/StarWarsTheCloneWars'', [[Recap/StarWarsTheCloneWarsS1E18MysteryOfAThousandMoons "Mystery of a Thousand Moons"]]: Anakin and Obi-Wan have to obtain a certain root only found on a moon of Iego that is the only known cure to the Blue Shadow Virus, and they only have a couple of days to do it.
279* ''WesternAnimation/StarTrekTheAnimatedSeries'' has this PlayedWith in the episode ''Pirates of Orion.'' The cure in question is rare, but can be arranged for easily enough (at least, if you are a Badass Starship Captain calling in a couple of favors to cut the red tape.) The problem is, it got stolen on the way by the titular pirates who mistook it for some other valuable substance.
280* ''WesternAnimation/TheSuperMarioBrosSuperShow'' had a twist: Snake-bitten Mario needed to eat a special antivenom pizza to be cured. They had the ingredients, but no way to cook it; Luigi had to find a ''fire flower''.
281* ''WesternAnimation/SuperNoobs'': Memnock and Zenblock in "License To Noob" fall ill to swink eye, a contagious space-oriented eye infection that causes blindness, swelling, itching, and discharge in its victims. They task the Noobs to get eye drops for them. This is a subverted case because The Noobs knew where to go to get the drops that are only produced and sold in the beta sector and Memnock and Zenblock couldn't get it themselves because of their blindness. The Noobs get distracted several times also through their irresponsibility with Memnock and Zenblock's spaceship and then having to help a princess save her planet from a race of bee-like people who all happened to have the same eye infection Mem and Zen had. The antidote itself for the condition is actually purple dust capable of curing those with swink eye within seconds.
282* Both ''Franchise/TeenageMutantNinjaTurtles'' cartoons featured variations of this trope.
283** In ''WesternAnimation/TeenageMutantNinjaTurtles1987'' episode "Enter the Fly", April was poisoned by inhaling the pollen from the Doku ("poison") plant, which had been sent to her by an "anonymous admirer" (actually The Shredder). The turtles must then search for the Gazai plant, which is the only source of the antidote.
284** In ''WesternAnimation/TeenageMutantNinjaTurtles2003'' episodes "Good Genes" part 1 and 2, it occurs when Donatello is infected with the mutagenic virus making its way across New York, which allows Agent Bishop to extort a favor out of them in exchange for a cure -- one that he doesn't actually have. Fortunately, the turtles' ally Leatherhead managed to invent one on his own by the time they got back from stealing the relevant MacGuffin.
285* ''WesternAnimation/TheTick'': In the Tick's case, it was explainable by the fact that the villain ''spilled'' his AppliedPhlebotinum at the Tick as a last-ditch attempt to dislodge him... Why the villain in question ''had'' an antidote to counteract it, less so.
286* ''Franchise/{{Transformers}}'':
287** Subverted in the ''Franchise/{{Transformers}}: WesternAnimation/BeastWars'' episode "The Low Road". An... ''unfortunate'' side effect of the virus and its interaction with some wild bean vines is what wins the day for our heroes. Needless to say, it's sort of a self-parody episode of a usually much-more-serious show.
288** ''Beast Wars'' also had a unique take on this in the episode "Gorilla Warfare". The Predacons infected Optimus Prime with a virus designed to make him a coward, planning to ambush the Maximals when they launch an attack to steal the cure. [[spoiler:However, incompetent virus creation turned Optimus into a berserker instead, making him tear through the Predacon base singlehandedly.]]
289* In ''WesternAnimation/{{Wakfu}}'' Episode 7, Amalia is bitten by a devil rose, and her companions have to find the only existing cure for the poison, a very rare sap from a magical tree, in a forest full of {{Man Eating Plant}}s.
290[[/folder]]

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