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9* ''Franchise/AssassinsCreed'':
10** The Borgias of ''VideoGame/AssassinsCreedBrotherhood'', albeit this is just an adaptation of their own, also-screwed-up RealLife selves. Even [[spoiler:Lucrezia's son]] Giovanni Borgia the Younger is not spared due to being warped by [[spoiler:the Shroud of Eden]], though he ends up leaving them to [[spoiler:join the Assassins]].
11** On the heroes side, we have the Kenways who in ''VideoGame/AssassinsCreedIII'' and prequel ''VideoGame/AssassinsCreedIVBlackFlag'' contain three generations of PlayerCharacter. Edward Kenway abandoned his wife for riches [[spoiler: and unknowingly fathered a daughter, Jenny Kenway who comes to have issues with him not being around]]. His son Haytham becomes the family BlackSheep, a Templar Grandmaster and becomes an ArchEnemy to his own son Connor, who [[spoiler: murders his ArchnemesisDad out of Self Defense when the former tried to strangle him]].
12** ''VideoGame/AssassinsCreedOdyssey'': The family drama around the main player's family is not great. Cassandra and Alexios were separated at birth and nearly killed due to the machinations of an ancient cult. Then one of them became said cult's "champion" due to an abusive childhood. Their Mother had to exile herself from Sparta for a while due to the shame brought on their family. Their birth father abandoned them [[spoiler: to guard ancient technology]], and their adopted father acquiesced to the deaths while then starting a new family whose son became aggressive and got into conflict with the Eagle Bearer later in life.
13* ''Franchise/{{BlazBlue}}'':
14** To summarize the story: [[spoiler:3 Orphan Siblings + TimeTravel + cloning + AxCrazy = Big Screwed-Up Family + TheEndOfTheWorldAsWeKnowIt [[GroundhogDayLoop Repeatedly]]]]. To specify, [[spoiler:the younger brother is driven to insanity by the BigBad, so he cuts off his big brother's arm, then later supervises a clone of his sister, whom he hates, who is a main piece in the Big Bad's plan to destroy the world, and is then driven to hunt his thought-to-be-dead big brother, who will also destroy the world, and it turns out the sister who disappeared is the villain behind the main antagonist. In the original timeline, the big brother was turned into a monster and sent back in time, while his younger brother turned himself into a hero to atone for everything he had done before. Even as a reformed hero, he is still intent on killing his big brother, though now he wants to do it for the sake of the world and not because of {{Yandere}} tendencies. Speaking of Yandere tendencies, there's also another clone of their sister who has some serious hots for Ragna, and when he rejects her she decides to kill him so that they can fuse and become the earlier mentioned world-destroying monster together... Yes, this game is ''very'' [[MindScrew confusing]]... Credit where credit is due, though: The family has become a little less dysfunctional by the end of the second game. Well, except that sister-turned-villain... Though all hope is not lost for this family, due to persisting rumors that this sister-turned-villain could be just a victim of manipulation of the BigBad and her villain status was just a front provided by the BigBad so he could move as he like and {{Troll}} the brothers]].
15** The Clover family. The father, [[EvilGenius Relius]], is a [[LackofEmpathy sociopath]] who turned his daughter into a machine and then used the experience to turn his wife into a superior version... ForSCIENCE All while, his [[ParentalAbandonment abandoned]] son, Carl, who was forced to finish the experiment that his father begun, because Relius couldn't be bothered to finish the job on Carl's sister, was understandably deeply traumatized by these events. He now greatly distrusts adults and will do ''anything'' to return his sister to normal and get revenge. When they eventually reunite? Relius brags about how he has [[LargeHam "ACHIEVED PER-FEC-TION"]] with his wife and promptly tries to [[OffingTheOffspring demonstrate her power on his children]].
16** [[MsFanservice Mak]][[CuteMonsterGirl oto]]'s family is heavily implied to be this in two of the [[PlayedForLaughs gag reels]] from ''Continuum Shift: Extend''. While a bit exaggerated in Makoto's own gag reel, it's still nowhere ''near'' as bad as what Ragna and Carl had to endure.
17--->'''Narrator:''' Mommy ends Mikoto's rant with [[ComedicSociopathy a wicked right cross to the mouth]] -- a textbook example of the famous Nanaya "tough love".\
18'''Makoto[[spoiler:-in-Ragna's-Body]]:''' Geez, [[EveryoneHasStandards and I thought my family was nuts]]!
19** And then there's the Yayoi dynasty, who have been trying to keep their magical power up through the generations by [[RoyalInbreeding keeping it in the family]] for far too long now. Put it this way: it's made explicitly clear that Tsubaki isn't the firstborn of her house, merely the first ''to survive''.
20* ''VideoGame/CliveBarkersUndying'' has the Covenant family, even ''before'' the last members were horribly cursed. It's hinted that the Covenant family has a dark history involving untimely deaths, creating all sorts of bloody rumors.
21* ''VideoGame/CragneManor'': Much like the Verlac clan from ''VideoGame/{{Anchorhead}}'', the Cragne lineage is very long and frequently very occult.
22* Most families in ''VideoGame/CrusaderKings'' end up this way after a while. Favorite gameplay example when playing as the Sverkers: Son gets "You have fallen in love with a girl in your court." event... With his SISTER. A week later sister gets "Death By Suicide". A generation later the son-and-heir assassinated his father...
23** You think that's bad? Try playing the ''Sword of Islam'' expansion. Muslim rulers can have up to four simultaneous marriages, and technically every child from all of them is legitimate. This means your wives will be doing a lot of plotting and political maneuvering to try and get their kid as heir to your throne. There's also the decadence mechanic for Muslim dynasties, which causes huge problems for dynasties with unlanded males: the only thing worse than a plotting family member is a plotting family member with their own land and armies... and family members who disgrace the family name by sitting around the palace all day drinking and chasing servant girls. If you're not the plotting type yourself, you can quickly end up feeling like your dynasty's OnlySaneMan.
24* Honorable mention goes to Kasumi, Hayate, and Ayane from ''VideoGame/DeadOrAlive''. Kasumi was sentenced to death because she was trying to find the (at the time) missing Hayate. Regardless of the reason, leaving the clan is punishable by death. And her own half-sister Ayane (who is a ChildByRape from her Uncle Raidou who is a clan outcast, (he raped Kasumi's and Hayate's mother Ayame the wife of Raidou's brother Shiden,) and thus was considered TheUnfavourite among the clan throughout her childhood) is the one trying to kill her. And you thought [[Franchise/MortalKombat Sub-Zero had it rough...]]
25* The Bray Family from the backstory of ''VideoGame/{{Destiny}}'', a wealthy clan of scientists and businessmen who operated prior to [[ApocalypseHow the Collapse]]. Most of the family were decent enough folks, but unfortunately, the family patriarch Clovis Bray I was [[BitchInSheepsClothing secretly a controlling, delusional sociopath]] with very rigid and specific ideas about how his family should turn out. He clumsily engaged in gene engineering on himself and his son in an inept attempt to become [[https://en.m.wikipedia.org/wiki/Last_universal_common_ancestor the next universal common ancestor]] (resulting in nearly all of the family suffering from [[https://en.m.wikipedia.org/wiki/Fatal_insomnia fatal familial insomnia]]), treated his adoptive granddaughter Ana with scorn for not being of the proper genetic stock, and [[spoiler:arranged the death and UnwillingRoboticisation of his biological granddaughter Elsie [[DisproportionateRetribution because she tried to shut down his pet project]].]] The effects this sort of behavior had on the rest of the Brays is [[DysfunctionJunction about what you would expect]], and by the story's present day the only surviving members are Ana (who was resurrected as a [[TheChosenMany Guardian]] after dying in the Collapse) and [[spoiler:Elsie, who is now [[MysteriousStranger the Exo Stranger]], a time-traveling robot fighting a one-woman war on [[MechanicalAbomination the Vex]].]]
26* ''VideoGame/TheElderScrollsIIIMorrowind'' has the Dren family. Vedam is the Duke of Vvardenfell, and a [[TheGoodKing good one]] at that if a little biased toward his own Great House. He has a CainAndAbel situation going on with his crime boss brother, Orvas, referred to in the editor as "Orvas Dren Druglord," who leads the Camonna Tong, a native Dunmer mafia-style gang of slavers, drug peddlers, and thugs who are extremely xenophobic. A late game quest (which also features into several faction quests) has you uncover evidence that Orvas is planning to assassinate Vedam. The Camonna Tong has bribed and extorted their way into the highest levels of leadership within House Hlaalu and the Fighters Guild, giving them massive influence and resources. Finally, there is Ilmeni, the daughter of Vedam who lives as a pauper in a lower-class area of Vivec. She's active in the Twin Lamps, an illegal slave ''freeing'' operation, which is directly opposed to her uncle Orvas on ideological grounds, and cannot be officially supported by her father because slavery is technically legal and protected in Morrowind.
27* ''VideoGame/EldenRing'': All of the demigods and children of Marika turned on each other after the Shattering, each vying with the others for the position of Elden Lord and laying complete waste to large sections of the Lands Between in the process, most notably with how Caelid was completely leveled by Malenia's scarlet rot in her battle with Radahn. The current situation is an uneasy stalemate, with cruel and secretive demigods like Godrick and Rykard completely dominating their spheres of influence, while others like Princess Ranni are still machinating away. Meanwhile, Morgott attempts to keep order in Leyndell out of a misguided sense of loyalty to the Golden Order and his father Godfrey, and his brother Mohg has kidnapped Malenia's brother Miquella in order to do...[[NothingIsScarier something unsavory]]. It's up to you as a Tarnished and aspiring Elden Lord to put an end to this gigantic familial squabble [[ViolenceReallyIsTheAnswer by killing some or all of them]].
28* In the ''VideoGame/FatalFrame'' series, many a family in close connection to the rituals in each game tends to be this, such as the Himuro family in ''I'' and the Kuze family in ''III''.
29* ''VideoGame/FireEmblem''
30** Most of the playable characters and major antagonists in ''VideoGame/FireEmblemGenealogyOfTheHolyWar'' are related, most of them by incest. [[spoiler: The entire playable first generation characters are either killed, tortured, or severely crippled by the villains with the exception of Sigurd, leading to the children attacking for revenge.]]
31** From ''[[VideoGame/FireEmblemFates Fire Emblem: Fates]]'', we have the royal family of Nohr, or what's left of it at any rate. It's fair to say that these guys have some ''serious'' issues, especially with regards to the children and their father. At one point in time, according to the accounts of his children, Garon was a pretty great parent. He was a compassionate father, a fair ruler to his subjects, and a loving husband to his mistresses... [[ReallyGetsAround yes mistresses]]. That should be the first clue that not everything is stable in that household. In fact, crown prince Xander is the only one related to his legal wife, with ''all'' of the other children having come from different mothers. He certainly loved them, but he just couldn't break off any ties to them after he fell in love, thus he kept them around as his mistresses. Unfortunately, his mistresses did ''not'' share that same love for each other, and the whole place devolved into a [[DecadentCourt battlefield]] between concubines. In this state of paranoia they would often resort to flat out murdering one another and in many cases each others' ''children'' (sometimes forcing said children to ''kill each other''), all in their efforts to garner Garon's favor. It got so bad that the royal family dwindled down to just Garon and his four remaining children (Xander, Camilla, Leo, and Elise) after the children resolved the issue of succession themselves. This experience left Garon a bitter and heartless shell of his former self, and traumatized his children so badly that they defer to his wishes, no matter how cruel they may be, all in an attempt to end the conflict currently going on with Hoshido, under the belief that with the war over he will return to his kinder self. [[spoiler: What they don't know is that Garon is actually dead and that his corpse is being possessed by a familiar to fulfill the plans of [[GreaterScopeVillain Anankos]] to destroy both Nohr and Hoshido.]]
32** Some families in ''VideoGame/FireEmblemThreeHouses'' are pretty F'd up. Bernadetta's father [[AbusiveParents abused her]] to make her a "perfect, submissive wife" that he could wed off to a wealthy noble, leading to [[ShrinkingViolet crippling anxiety]]. Sylvain's family places so much emphasis on the possession of a Crest that they disowned his Crest-less elder brother after he was born; said brother would eventually become a brigand [[spoiler:and die horribly]]. And that's all before getting into the house leaders: [[spoiler:Edelgard is the SoleSurvivor among her siblings after they were kidnapped and experimented upon by those who slither in the dark (for a mercy, though, her father is a caring man). Edelgard is also related by marriage to Dimitri, her biological mother being Dimitri's stepmother. As revealed in Azure Moon, however, Dimitri's stepmother was a turncoat who played a large role in a massacre that claimed the lives of his family. Meanwhile, Claude is the illegitimate grandson of the leader of the Leicester alliance: his mother, Duke Riegan's daughter, eloped with the king of the rival nation of Almyra. As a result, he has faced FantasticRacism among both Almyrans and the people of the Alliance as a biracial child.]]
33* In ''VideoGame/FirstEncounterAssaultRecon'', you're a [[HeroicMime mute supersoldier]] known as the Point Man. The man you've been sent to kill, Paxton Fettel ([[spoiler:who is your brother]]) is a cannibalistic, psychic psychopath who is going on a violent rampage with his army of telepathic soldiers and merely gets pissed when you kill him. Alma [[spoiler:Wade]] ([[spoiler:who is your mother]]) is a homicidal ghost out for revenge (and to protect [[spoiler:her children]]). Harlan Wade ([[spoiler:your grandfather]] [[spoiler:''AND'' technically your father]]) is the person who caused this mess by working with an evil corporation to experiment [[spoiler:on his own daughter who happens to be the aforementioned ghost that is your mother]]. Note that this is just the ''first'' game. In the second one, Alma decides to add [[spoiler:Michael Becket]] to your relations by [[spoiler:[[StalkerWithATestTube using him to father another child]]]], but this is ''after'' a gene-splicing operation that [[spoiler:directly links him to your bloodline]]. By the third game, Alma is expecting ''again''. On top of that, [[spoiler:while grandpa is still dead, the worst parts of him are ''back'' and want you dead too]]. And at the very end, [[spoiler:the Point Man and Fettel face off, and one of them gets killed/consumed, leaving the other to raise the newborn as their own]].
34* Later ''Franchise/FiveNightsAtFreddys'' games depict the Afton family as this. Let's put it this way: most of the established members have either tried or ''succeeded'' in killing each other at least once. The father, William, is the BigBad, who is a SerialKiller of [[WouldHurtAChild children]], has confined his victims to an unlife as HostileAnimatronics, and has created animatronics with the specific purpose of finding new victims. The daughter, Elizabeth, [[spoiler:was killed by one of these animatronics, and later -- as Circus Baby -- went on to use her brother's hollowed-out corpse as a disguise before [[DaddysLittleVillain supporting William in his crimes.]]]] Speaking of which, [[spoiler:said brother, Michael, is heavily implied to be the BigBrotherBully from [[VideoGame/FiveNightsAtFreddys4 the fourth game]], who accidentally killed his younger brother in a DeadlyPrank.]] By the way, [[spoiler:[[RevenantZombie Michael is still alive after having his body used as an animatronic's suit]]. It's also implied that his ongoing trauma is in part because he [[StrongFamilyResemblance looks a lot like his father]].]] For bonus points: [[spoiler:Vanny, the [[BrainwashedAndCrazy brainwashed]] [[JackTheRipoff copycat killer]] and minion of William's VirtualGhost starting from ''Help Wanted'', is referred to as 'Vanessa A.' in the ''Special Delivery'' lore emails, which means that there's a [[AmbiguouslyRelated non-zero chance of her also being an Afton]].]]
35* In ''VideoGame/HauntingGround'' -- the Belli family. Ugo was [[OnlySaneMan the only normal child]] and he escaped when he met Fiona's mother.
36* ''VideoGame/{{LISA}}'' has the Armstrong Family, which is filled with all manner of seriously messed-up people.
37** Marty, the family's patriarch, is an untidy, dirty, and abusive drunkard who regularly molests his daughter [[spoiler: and potentially forced his son to watch, or possibly even do the same]].
38** Marty's children, Lisa and Brad, had no control over their own childhoods, as their father ruined most of their aspects, [[spoiler: to the point where Lisa was DrivenToSuicide]]. Lisa had also become psychologically-manipulative as a way to cope with her abuse, which lead to her driving [[spoiler: her boyfriend, Bernard/Buzzo]], to complete madness. Brad made his greatest attempt to live a happy life, only for his Joy addiction and excessively-violent demeanour (alongside various other factors) to completely ruin him, [[spoiler: even in death]].
39** [[spoiler: Dustin/Rando, Brad's adoptive-son, was an extremely meek and cowardly child, which he made an attempt at addressing by having Brad train him in martial-arts. However, this training would prove worthless in protecting Dustin from his horrific facial-disfigurement at the hands of Bernard/Buzzo. He still shows his mild and gentle demeanour throughout ''The Painful'' and ''The Joyful''; he has little control over his own army, and he begrudgingly works with Buddy to murder the other Olathian warlords, which directly goes against his attempts to keep Olathe as peaceful as possible. Thankfully, he ends up becoming more tough and hardened by the end.]]
40** Buddy, Brad's adoptive-daughter, was initially the least screwed-up member of the Armstrong Family. However, once she becomes the most important person in the entirety of Olathe, she becomes increasingly distrustful of everyone around her, especially Brad, considering the many unsavoury acts that he performs in his Joy-induced attempts to save and protect Buddy. Brad quickly becomes the brunt of Buddy's mixture of sadness and anger, with her realizing that her own adoptive-father is the primary reason that her life is so difficult. This continues into ''The Joyful'', where she becomes a psychopathic and overbearing wanderer who holds no remorse in murdering anyone who gets in her way of becoming the most powerful person in Olathe.
41* The Drevis family in ''VideoGame/MadFather'' have a great list of issues. Aya's father, the titular mad father, killed animals and people [[spoiler:including his own mother]] when he was a child, experiments on people and animals as an adult, [[spoiler:killed his wife and plans to turn his daughter into a doll, which he's done for his previous victims.]] Aya's mother reads very disturbing books to her young daughter, [[spoiler:developed feelings for her husband after he refused to kill her and was excited by the prospect of her daughter growing up to be like her father.]] Then there's Aya herself. She loves her father regardless of what he's doing in the basement, enjoys playing with a mini chainsaw, [[spoiler:has killed small animals as her father had, and is implied to be continuing her father's experiments in the True End]].
42* In the RPG Maker game ''VideoGame/MermaidSwamp'' there is the Tsuchida family. In the game, there is a legend of a man who kidnapped a mermaid and kept her alive with swamp water only for her to die, and now the mermaid wants vengeance. [[spoiler: In reality, there is no mermaid and the entire legend was fabricated by the women of the Tsuchida family in an effort to keep travelers away from their village. Turns out that the men of the Tsuchida family have a strong romantic attraction for women who are underwater and they would kidnap girls from the village in order to force them to live in tanks. The fact that the girls would become sick and eventually die did not bother them in the slightest. That's what preservatives are for.]]
43* ''VideoGame/MetalGear''
44** The Snake family. First off, we have Big Boss, who is the most gifted soldier of the 20th century and would be recognized by America as their greatest asset, but after many hardships, betrayals, and tragedies were thrown his way by the government he swore his life to, especially by being ordered to murder his former Master turned multinational terrorist, The Boss, he became disillusioned and drifted the world as a mercenary. Eventually, his disillusionment reached such a point that he sought revolution, overthrowing America and the corrupt forces behind it, the Patriots, who controlled everything in secret, thus bringing a new birth of freedom to the country. Meanwhile the Patriots cloned Big Boss so as to have copies of the greatest living soldier in the world to use at their disposal, and the sons of Big Boss would go on to agree with their father's stance (Liquid and Solidus both try making their own Outer Heavens) and have feuds with their genetic father (Snake and Liquid fought him) along with each other (reaching its peak with a scene where the Liquid-possessed Ocelot challenges both Snake and Solidus in the middle of those two already fighting each other). The protagonist of the series Solid Snake would eventually defeat his father in single combat, being the lapdog of America that Big Boss had once been. Liquid Snake, failing in his feud with Big Boss, took up his cause in order to prove he was better than his father by succeeding in the dream of defeating the Patriots where his father had failed, and Solidus the third son takes up his father's cause to recognize his own independence, but both brothers are stopped in part by their brother Solid Snake just as he had stopped their father. The Snake family only knows how to fight one another, which comes off as sad as all of them have noble causes but they all get manipulated so that they have to fight each other, and even when this is brought to their attention their differences are never settled. Also Ocelot, who's The Boss's son, but comes to admire Big Boss as a father figure, too, in his own way. He pretends to work with both Liquid and Solidus only to backstab both of them all while fighting Solid Snake, this being after the years he already fought then joined their father. Finally, Solidus takes on the soldier who would become Raiden as a ChildSoldier adoptive son, only for Solidus to acknowledge that he is Raiden’s answer to Solid and Liquid’s Big Boss, leading to the two of them fighting and Raiden killing Solidus, going on to be mentored by Snake instead.
45** The Emmerich family, as elaborated upon in ''Metal Gear Solid 2'', ''Peace Walker'', and ''Phantom Pain''. Otacon's [[DepravedBisexual birth mother]] saw him as a potential child soldier to replace The Boss, [[MadScientist his father]] saw him as a ''giant mecha test pilot'', and [[AbusiveParents his stepmother]] saw him as her ''sexual plaything''. This all culminated in Otacon’s father Huey attempting to drown Otacon’s step-sister Emma in their swimming pool, leading to his own death and Emma’s fear of water. Emma then goes on to become [[ConspiracyTheorist paranoid]] and also psychotic towards Otacon for not being there when she needed him the most (which unbeknownst to her, was while he was being raped by her mother) and ultimately tried to bring human civilization crashing to the ground for the sins of all of the above, which had varying results when her global network-crashing virus was modded by cooler heads but successfully deployed.
46* ''Franchise/MortalKombat'':
47** [[BadassFamily As badass as they may be]], we see some serious family issues between [[spoiler:Younger Sub-Zero and Noob Saibot]] and [[spoiler:Kitana and Sindel]] in ''VideoGame/MortalKombat9''. Both involve extensive amounts of [[KickTheDog puppy-kicking]] from Person B, and the latter example actually culminates with the ''death'' of Person A.
48** ''VideoGame/MortalKombatX'' has even more family drama. First, we have the Cages: Johnny Cage and Sonya Blade married and had Cassie, then divorced, with Johnny and Sonya sniping at each other while Cassie tries to win her mother's approval. Next, Kenshi and his son Takeda: Kenshi left Takeda in the care of Scorpion and the Shirai Ryu to pursue the ones responsible for the death of his mother, and Takeda resented him for being a DisappearedDad. Finally, Jackson Briggs and his daughter Jacqui: he does not approve of her being in Special Forces. All this before we get into the fact that they can fight (and brutally murder) one another in-game.
49* While not especially powerful, the generational family that forms the core of the ''VideoGame/{{Myst}}'' games fits this trope far better than any mere dysfunctional family:
50** Ti'ana (great-grandmother) managed to cause a civil war in an ancient civilization (granted, not her fault).
51** Aitrus (great-grandfather) got vengeance on the man who killed his family by trapping him in another world ''and destroying it''.
52** Gehn (grandfather) set himself up to be [[AGodAmI worshiped as the god]] of multiple private universes, keeping his subjects in check by feeding dissidents to his pet beasties.
53** Atrus (father) is [[ScienceRelatedMemeticDisorder a little too concerned with his research]] and not concerned enough with raising his family, and ultimately [[ItsUpToYou relies on other people to solve most of his problems]].
54** Katran (mother) was (and presumably still is) worshiped by rebels against Gehn, and represses a few things about her sons that she'd [[LoveMakesYouDumb really be better off concerning herself with]].
55** Achenar (elder brother) is [[spoiler: an AxCrazy psychopath with a macabre taste in decoration and a penchant for ElectricTorture]].
56** Sirrus (younger brother) is [[spoiler: a narcotics abuser and MadScientist with serious [[CainAndAbel sibling rivalry issues]]. He and Achenar plundered the dozens of populated worlds, massacring their inhabitants and wrecking their ecosystems, then imprisoned their father and trapped their mother in a universe with Gehn, who wants her dead]].
57** Yeesha (younger sister) is a bit of a creepy but naive {{Cloudcuckoolander}} who [[spoiler: helps her brothers escape their prisons by mistake, is briefly imprisoned in [[JourneyToTheCenterOfTheMind Dream]] and [[GrandTheftMe possessed]] by her older brother]] and comes out of the whole mess with a [[MessianicArchetype Messiah complex]] and [[ProphecyTwist an inability to communicate clearly]].
58*** Oh, yeah. And just about all of them are capable of carefully RewritingReality. [[spoiler:''Especially'' Yeesha, who is apparently right about being the Messiah.]] This bodes not well.
59* ''VideoGame/NoMoreHeroes'' features the Touchdown family, which in the last 10% of the game is revealed to be incredibly expansive. There's Travis Touchdown, otaku assassin; [[spoiler:his mother, murdered; his father, who cheated on Travis's mother with another woman, who committed suicide, resulting in the murder of himself and his wife at the hands of his mistress's daughter Jeane (who Travis was dating, unaware that she was his half-sister); this is all revealed after Jeane kills Dark Star, the number 1 ranked assassin who also claims to be Travis's father. In an unrelated plot, Travis discovers that his rival, Henry, is actually his twin brother, and is married to Sylvia, the woman Travis was pursuing. And they have a daughter, also named Jeane. You might as well count Travis's cat, Jeane, as part of the family to round out the hat-trick]].
60* A good bit of the cast of ''VideoGame/OdinSphere'' turns out to make up one big RoyallyScrewedUp family:
61** Demon King Odin's legitimate daughters Griselda and Gwendolyn are desperate for his love and approval to the point that they long to die in battle in the hopes that it will prove their worth to him; Griselda ''does'' die in the opening of the first leg of the game, and Odin uses Gwendolyn's longing for his affection to manipulate her throughout nearly her entire book.
62** Odin also has two illegitimate children, Velvet and Ingway, from an affair with Princess Ariel of Valentine. Seeing his beloved daughter give birth to his enemy's children caused King Valentine to ''snap'': he forced Velvet and Ingway to renounce their mother and claim they never loved her, executed Ariel, and abused and terrorized both twins, Velvet especially. Thanks to Velvet's UncannyFamilyResemblance to her mother, she's the only one of Odin's children he shows any affection towards, while she blames him for her mother's death and wants nothing to do with him; meanwhile, Ingway [[spoiler:destroyed the entire country of Valentine in order to save Odin from dying in battle against Valentine's superior army]] only for Odin to dismiss him with a callous, "Well done, traitor."
63** Gwendolyn eventually marries Shadow Knight Oswald, the adopted son of Melvin, who is the cousin of the Fairy Queen of Ringford. Melvin adopted Oswald when he found him abandoned as an infant, and even after Melvin sold Oswald's soul to the Queen of the Netherworld in order to make him the Shadow Knight, Oswald is fanatically loyal and obedient towards him right up until Melvin [[spoiler:dies in a failed attempt to seize the throne from Queen Mercedes and admits in the process that he never saw Oswald as anything but a tool with which to take over Ringford]]. Unbeknownst to Oswald, his real father was actually [[spoiler:the exiled Prince Edgar of Titania, who renounced his claim to the throne in order to marry a peasant woman, and who was assassinated for it by his father King Gallon. This makes him the cousin of Prince Cornelius of Titania, whose father King Edmund was forced to take up a magic sword and kill his own father after King Gallon turned himself into a monstrous man-eating beast and ravaged his own country]].
64* The ''VideoGame/PowerInstinct'' series concerns the endless infighting of the Goketsuji clan, which has branches all over the world, ''none'' of which get along.
65* The Baker family of ''VideoGame/ResidentEvil7Biohazard'' consists of three psychotic murderous and apparently invincible hillbillies and their [[TokenGoodTeammate apparently not psychotic or murderous daughter]], as well as the CreepyChild Evelyn and the apparently catatonic grandmother. [[spoiler:Subverted in that they actually were once a loving family who were [[BrainwashedAndCrazy infected and brainwashed]] by the [[HumanoidAbomination bio-weapon Evelyn]] and turned from a perfectly normal family into a group of murderous mold-monsters, save for Lucas who [[EvilAllAlong was always evil and was never brainwashed]]. Also Evelyn and the grandmother are actually the same person, but that's a tale for another trope.]]
66* ''VideoGame/ShadowrunReturns'': Poor Marie-Louise. Her father is a CorruptCorporateExecutive who had her boyfriend crippled because he disapproved of him, her mother is dead, two of her aunts are the leaders of the local chapter of the world's largest PathOfInspiration, her half-aunt hired a SerialKiller to harvest organs from people in order to put her dead mother back together, and her estranged uncle is a serial addict, career criminal and sometime mercenary.
67* In ''VideoGame/TheSims2'', the Curious/Smith/Singles family sprawls diagonally over Strangetown, dominating the town's drama. Apparently, it all started when Glarn Curious was abducted by an alien [[FaceFullOfAlienWingWong pollination technician]]. Sick of caring for his alien daughters, Glarn abandons them to wife #1 Glabe, took off and remarried to Kitty, proceeded to have four children with her the old-fashioned way, one of whom proceeded to ''marry the alien who inseminated him'' and have two kids of her own. Then the younger son Pascal, err, followed in his father's footsteps, and is "expecting" at the beginning of the game. If you play your cards right, brother Vidcund can reach the same happy state shortly thereafter, by the same alien daddy -- leaving you with two adorable green babies who are both cousins and siblings. Not to mention the Singles sisters and the Smith kids, who are both paternal half-siblings ''and'' aunts/niece-nephew.[[http://sims.wikia.com/wiki/File:Curious-Smith_Family_Tree.png Check out this fancy family tree]] including the antecedents from ''VideoGame/TheSims3''.
68** It should be noted, however, that, outside of the odd relationships, the family is perfectly functional and loving, even moreso than some of the more "normal" families in Strangetown.
69* ''Videogame/{{Smite}}'' has various gods from the Greco-Roman, Egyptian and to a lesser extent Norse Pantheons so this is a given. Using their historical counterparts as a basis:
70** Egyptian: Neith is the mother of Sobek, Serqet, Khepri, and Ra, who is the father of Anhur and Bastet. He is also (through his son Shu) the grandfather of Nut and Geb, who are the parents of Eset and Osiris. Osiris, in turn, is the father of Anubis through his sister-in-law Nephthys, who disguised herself as Eset due to her husband/Osiris' brother Set being sterile. Eset herself has a legitimate son, Horus, who could be argued to have created Thoth. Most of the screwed up revolves around Ra. That's every playable character in the pantheon, just so you know.
71** Greek: Poseidon, Hades, and Zeus are brothers who don't like each other very much. The latter is the father of Apollo, Artemis, Ares, Athena, and Aphrodite. Thanatos and Nemesis are siblings, and cousins once removed to Zeus (their mother Nyx is the sister of Zeus' grandmother Gaia). This isn't including the zig-zagged relations they have with the Roman gods.
72** Roman: Bellona, Bacchus, Hercules, Mercury, and Vulcan are all siblings. Nox is their great-great aunt. Cupid is their nephew. With opinion leaning more towards the Roman gods being the same as the Greeks, we can now add all of them to the mix, with the sibling sets of both Pantheons being siblings to each other (10 kids and counting; Zeus has been busy), Vulcan being married to his sister Aphrodite, Cupid being the son of Aphrodite and Ares, and Nox being Thanatos' and Nemesis' mother and Zeus', Poseiden's and Hades' great aunt. The upcoming god Charon is also the son of Nox and brother of Thanatos and Nemesis.
73** Norse: Borr married one of Ymir's descendants, from whom Odin was born. Thor is his son. Loki is the father of Hel and Fenrir. Ullr is Thor's stepson (son of Thor's wife Sif and an unknown father).
74** Among the rest, Hou Yi and Chang'e are husband and wife, and He Bo is brother of Chang'e; Xbalanque and Hun Batz are half-brothers (same father, Hun's the older), and Awilix and Ixbalanque are technically the same person (Ixbalanque is the incarnation of Awilix); Ravana and Kumbhakarna are brothers, and Vamana and Rama are ''technically the same person'', Vishnu.
75* In ''VideoGame/SolatoroboRedTheHunter'', the relationship Red has with his adoptive sister Chocolat is as healthy as it can be for a brother-sister freelance duo. [[spoiler:The relationship Red has with his ''genetic'' family is another story. His father Baion is the BigBad who wants to commit mass genocide against the entire planet he lives on, his mother Merville, while well-intended, accidentally aligned herself with a corrupt military organization that tried to kill him multiple times, and he has six brothers and sisters, Carmine, Rose, Vermillion, Rouge, Nero, and Blanck. Vermillion, Rouge, Nero, and Blanck all tried to kill him and sees him as a genetic failure, and despite once having a close relationship with Carmine and Rose, they were responsible for wiping Red's memory prior to the events of the game in a rushed attempt to protect him from his own PowerIncontinence as a child]].
76* The Robonik family from ''Franchise/SonicTheHedgehog'' has the dubious honor of having almost every member attempt to take over or destroy the world AND attempt to kill a relative. Gerald went nuts and pulled a ThanatosGambit involving a ColonyDrop, his "son," Shadow, almost destroyed the world out of revenge, and later killed his "father," Black Doom, who intended to reduce humanity to cattle. Gerald also made the Biolizard and has a grandson in the form of Ivo Robotnik, AKA Dr. Eggman, who has attempted to take over the world too many times to count, manipulated Shadow (who is technically his uncle, mind you), and built Metal Sonic, who betrayed him at one point. The WhiteSheep of the family, Maria, was the equivalent of an AIDS patient who was killed by government agents at twelve.
77* ''VideoGame/StrayGods'' plays with the trope involving the Greek pantheon. While the Idols aren't actually related to one another, they played at being a family so long that, for all intents and purposes, they are one, with all the baggage that being a Greek God comes with.
78* The Mishima family from ''Franchise/{{Tekken}}''. It's {{badass|Family}}... and it's also ridiculously shattered. By ''Tag Tournament 2'', there are certifiably ''five'' family members competing. There's Jinpachi, his son Heihachi, his son Kazuya, ''his'' son Jin Kazama, and Heihachi's illegitimate son Lars Alexandersson (there is also Heihachi's adoptive son Lee Chaolan, although his involvement with the "family business" varies). You can basically draw a web of who wants to kill who and why. The only one who is 'good' in the general sense of the term is Jinpachi (he has a good heart but is unable to fight the engulfing evil force that has possessed his mind and body; although Lars is heroic his disgust with his parentage does cause him to shoot at Heihachi unprovoked when the two cross paths). This basically all starts with Heihachi, who tried to overthrow his dad, and threw his son Kazuya into a ravine to kill him, and ''then'' a volcano when that didn't take. Jin's family on his mother's side is relatively sane [[spoiler:though his mother Jun has a creepy SuperpoweredEvilSide (in the ''Tag'' games, at least) and terrible taste in men (she did fall in love with Jin's father Kazuya and still thinks he can be redeemed, ''despite'' him attempting to murder her niece)]]. Jin's cousin Asuka doesn't really get too involved with family affairs since she's kinda busy with her RichBitch rival constantly pestering her for fights, but she does try to kick Jin's ass in ''6'' for [[WellIntentionedExtremist causing all sorts of chaos in his plan to get rid of his Devil Gene]]. In ''VideoGame/Tekken7'', Heihachi's estranged wife Kazumi joins the fray and goes as far as [[GuestFighter hiring Akuma]] from ''Franchise/StreetFighter'' to take out Heihachi and Kazuya. She's [[spoiler:also the originator of the Devil Gene that plagues her grandson so much]]. As if all that wasn't enough, ''VideoGame/Tekken8'' adds in [[spoiler:Reina, who is actually Heihachi's illegitimate daughter, secretly planning to reclaim the Mishima Zaibatsu and honor the legacy of her father (who was KilledOffForReal at the end of ''7''). She also has a Devil Gene of her own... [[AmbiguousSituation somehow]]]].
79* The [[NameOfCain Kane]] family in ''VideoGame/TwistedMetal'', who often end up fighting each other in the titular DeadlyGame. Over the series' multiple timelines, the Kanes are always messed up one way or the other. Needles is the MonsterClown son, a SerialKiller and the BlackSheep of the family. Charlie Kane is the father, an old taxi driver who in the original, is fine with having killed his clown son in the tournament. In ''Black'', Charlie is killed and [[CreepyChild his unnamed younger son]] turns him into a reanimated corpse and ends up fighting his older brother Needles in the tournament. Marcus Kane, seemingly Needles' brother and another son of Charlie's, is revealed in ''Head-On'' to be the same person as Needles, in a case of SplitPersonality.
80* The Entrati family on Deimos in ''{{VideoGame/Warframe}}'' is a small nuclear family who ''all hate each other'' for various reasons. [[TeethClenchedTeamwork They will work together when shit hits the fan,]] but otherwise their conversations involve a lot of sniping at each other and bitter arguments. The only one who seems to be exasperated by all this is the grandmother, [[spoiler:who deliberately damages the Heart of Deimos in order to force her kids and grandkids to work together for once.]]
81* ''VideoGame/{{Xenosaga}}'' has a good example of this in the form of the Yurievs. You have father Dimitri, who is ReallySevenHundredYearsOld, a {{Body Surf}}er, and a WellIntentionedExtremist (on the surface), among other things. Next, we have the mother(s) who, for all we know, could have been used as ThePawn. Then there's big brother Jr (Rubedo), who's [[OlderThanTheyLook older than he looks]], being raised by his younger brother as his son (at least, to the public eye), and [[spoiler:the "Link Master" in an experiment to control and defeat the existence known as U-DO (later revealed to be God itself)]]. After that, there's [[spoiler:Rubedo's conjoined twin,]] Albedo Piazzola, who gets less and less mentally stable as he grows up. As a child, he was the CreepyChild and generally shows traits of UndyingLoyalty towards Jr. However, after finding out he was immortal and his siblings weren't, he went off the deep end, winding up to be a LargeHam, PsychoForHire, [[StrawNihilist Nietzsche Wannabe]], and WickedCultured as an adult. Following up is Gaignun (Nigredo), who seems to be mostly normal, even hinted at being [[WiseBeyondTheirYears wise beyond his years]]. However, it's revealed that [[spoiler:he was responsible for killing Rubedo, should his special power, Red Dragon, ever get out of control. Also, he killed Dimitri in an attempt to free himself from this, as well as his other purpose, which was to serve as a body should Dimitri ever have to BodySurf]]. Also, [[spoiler:he dies near the end of the third game, eliminating Dimitri in the process as well]]. Which leaves Citrine, the only woman actually shown in the family. Put simply, she's a ChekhovsGunman whose only purpose was to also [[spoiler:kill Rubedo in case his power went out of control]]. Also, she's the only one of the family who still sees Dimitri on a regular basis. Last are the other 665 other siblings, who were created to be standard [=URTVs=] (basically the counter to the existence, U-DO), with Rubedo, Albedo, Nigredo, and Citrine as the variants (who get more attention, stronger abilities, and a bad case of ThemeNaming). Also, all of the standard units are [[spoiler:all dead]]. And, quite honestly, this doesn't even begin to explain everything...
82* Look no further than the Fact family from the ''VideoGame/{{Ys}}'' series. The Stoddart family in ''VideoGame/YsTheOathInFelghana'' isn't much better. The Clan of Darkness also counts, with some members wanting to become all-powerful and take over everything or start an apocalypse, other members trying to atone for their ancestors' crimes and therefore getting into conflicts with the first group, and at least one member doing a HeelFaceTurn.
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