History Tearjerker / ResidentEvil6

* We learn that Sherry Birkin's life has not significantly improved since we last saw her in RE2. With both of her MadScientist parents dead, she spends the rest of her childhood and early adulthood being held by the US government as a test subject. It turns out that the G-Virus was still inside her, despite her being ostensibly cured in RE2. The only upside of all this is that the G-Virus grants Sherry a HealingFactor.

* At the beginning of the trailer for [=RE6=], Leon is forced to kill the President of the United States, who has become infected with the C-Virus and turned into a zombie. Keep in mind that he's a personal friend of Leon, one that had been there for almost ten years of Leon's life. He was the one who recruited Leon in the first place. It could be argued that Adam is his best friend, one that Leon was forced to kill.

** In contrast, Leon ''should'' already be pretty used to killing zombies. In [=RE2=], he averted NotAZombie as soon as the game began, he even was forced to shoot his would-be co-workers in [=RE2=]. Yet when he sees his good friend of like ten years turn into a zombie, Leon is is so stricken with grief that can't do anything but point his gun at what's left of his friend and call out in vain to get him to stop.
-->'''Leon:''' [[SayMyName Adam!]]

* Piers' HeroicSacrifice, staying behind to give Chris a better chance to escape, knowing he'll likely lose his humanity to the C-Virus soon. Between his look of silent regret and Chris' painfully desperate pleading for him not to go through with it, it's [[SincerityMode genuinely hard to believe this comes from the same series that gave us the]] "[[{{Narm}} Jill Sandwich]]."

* Leon being told by Chris [[spoiler:that Ada is dead. He's struck silent for a moment, and all he can respond with is a very soft, quiet "Copy."]]
** If [[spoiler:Ada ''had'' really died]], Leon would have lost two people he treasured in his life: his good friend Adam and [[spoiler:his love interest, Ada]].
* [[spoiler:Piers' HeroicSacrifice, staying behind to give Chris a better chance to escape, knowing he'll likely lose his humanity to the C-Virus soon.]] Between his look of silent regret and Chris' painfully desperate pleading for him not to go through with it, it's [[SincerityMode genuinely hard to believe this comes from the same series that gave us the]] "[[{{Narm}} Jill Sandwich]]."

** Also, Helena [[spoiler:trying to stop Leon and Ada from shooting Mutant!Deborah. Helena is fiercely protective of her sister, and her face when Deborah succumbs to the C-Virus can be heart-wrenching.]]
*** Plus, [[spoiler:Deborah still attempted to help her sister by shoving her away]].

* [[spoiler:Finn's]] death in Chris's campaign. Especially since [[spoiler:he's reaching to grab Chris's hand before becoming a cocoon.]] You can tell that Chris is ''pissed''.
** [[spoiler:As well as the rest of his team in Edonia. You really didn't know them, but it's hard not to feel sad about watching the entire team die while Chris is powerless to do anything]]. The result theme does not help at all after the chapter's been beaten.

** To further elaborate, we see [[spoiler:Chris is back in the Eastern European bar, quietly eating the same steak dish as Piers. We see a BSAA soldier walking into the bar and his face is kept hidden until he reaches Chris. Chris seems just as disappointed as the viewer when he realizes it's not Piers.]] Way to twist the knife, Capcom.
** In chapter 2 of Leon and Helena's campaign, an old man in Tall Oaks Cathedral says that his son, [[spoiler: Marco]] is part of the BSAA and will arrive with the whole army. It will never happen.
*** When he died and you retrieve his C4, it doesn't just say "C4 Explosive", it specifically states that it was [[spoiler: Marco's]] C4 Explosive.