- 50/50 Heroes
- Action League NOW!
- Action Man (2000)
- Action Pack
- The Adventures of Batman
- The Adventures of Hyperman
- The Adventures of Kid Danger
- American Dragon: Jake Long
- Aquaman
- The Aquaman & Friends Action Hour
- Aquaman: King of Atlantis
- The Atom Ant Show
- Atomic Betty
- Atomic Puppet
- Avengers Assemble
- The Avengers: Earth's Mightiest Heroes
- The Avengers: United They Stand
- The Awesomes
- Bananaman
- The Batman
- Batman: The Brave and the Bold
- Ben 10:
- Beware the Batman
- Big Hero 6: The Series
- Black Panther (2010)
- Bionic Six
- Birdman (1967)
- The Boys: Diabolical
- Captain Flamingo
- Captain Planet
- Captain Sturdy
- The Condor
- Cybersix
- Danny Phantom
- Darkwing Duck
- DC Animated Universe
- DC Super Hero Girls (web series)
- DC Super Hero Girls (TV series)
- Defenders of the Earth
- Delilah & Julius
- Dr. Dimensionpants
- Dynomutt, Dog Wonder
- The Epic Tales of Captain Underpants
- The Fantastic Four (1967)
- The Fantastic Four (1978)
- Fantastic Four: The Animated Series
- Fantastic Four: World's Greatest Heroes
- Fantomcat
- Freakazoid!
- Frankenstein Jr.
- Freedom Fighters: The Ray
- The Galaxy Trio
- Gargoyles
- Generator Rex
- Ghost Force
- The Governator
- Green Lantern: The Animated Series
- Groove Squad
- Hamster & Gretel
- Harley Quinn (2019)
- Harvey Birdman, Attorney at Law
- The Haunted World of El Superbeasto
- Hero Elementary
- Hero High
- Hero Inside
- Hijitus
- Hit-Monkey: A more downplayed example; the series focuses more on assassins and political intrigue but several Marvel superheroes and villains do appear and play major roles.
- The Hollow
- Hulk and the Agents of S.M.A.S.H.
- The Impossibles
- The Incredible Hulk (1982)
- The Incredible Hulk (1996)
- Invincible (2021)
- Iron Man: The Animated Series
- Iron Man: Armored Adventures
- Jenny Justice
- Justice League Action
- Kid Cosmic
- Kim Possible
- Kiya and the Kimoja Heroes
- Koala Man
- Krypto the Superdog
- League of Super Evil
- Legion of Super Heroes (2006)
- Legion of Super-Heroes (2023)
- Loonatics Unleashed
- The Magician
- Marvel Rising
- Marvel's Spider-Man
- The Marvel Super Heroes
- Max Steel (2013)
- The Mighty Heroes
- Mighty Mightor
- The Miniavengers
- Minoriteam
- Miraculous Ladybug
- M.O.D.O.K. (2021)
- Moon Girl and Devil Dinosaur (2023)
- My Adventures with Superman
- My Life as a Teenage Robot
- The New Adventures of Batman
- The New Adventures of Superman
- Phantom 2040
- Pith Possum
- PJ Masks
- Plastic Man
- Powerbirds
- The Powerpuff Girls (1998)
- Pryde of the X-Men
- Randy Cunningham: 9th Grade Ninja
- The Ripping Friends
- Road Rovers
- Robotboy
- Roger Ramjet
- SheZow
- Sidekick
- Silverhawks
- Silver Surfer: The Animated Series
- Skysurfer Strike Force
- Space Ghost
- Space Sentinels
- Space Stars
- The Spectacular Spider-Man
- Spider-Man (1967)
- Spider-Man (1981)
- Spider-Man and His Amazing Friends
- Spider-Man: The Animated Series
- Spider-Man: The New Animated Series
- Spider-Man Unlimited
- Spider-Woman
- Stan Lee's Superhero Kindergarten
- Steven Universe
- Stretch Armstrong and the Flex Fighters
- Stripperella
- Super Drags
- The Super Globetrotters
- Super Robot Monkey Team Hyperforce Go!
- The Super 6
- Superfriends
- The Superhero Squad Show
- Ruby-Spears Superman
- Street Sharks
- Super Friends
- SuperMansion
- Superman Theatrical Cartoons
- SuperTed
- Super Why!
- Sushi Pack
- SWAT Kats
- Tales of Arcadia
- Teamo Supremo
- Teen Titans (2003)
- The Tick
- El Tigre: The Adventures of Manny Rivera
- Todd McFarlane's Spawn
- Toxic Crusaders
- Transformers: Animatednote
- Turbo Teen
- Ultimate Spider-Man (2012)
- Underdog
- The Venture Bros.
- Villainous (Cartoon Network): Centered around an organization of supervillains and superheroes show up as antagonists.
- Vindicators 2
- Vixen
- What If…? (2021) (part of the otherwise live-action Marvel Cinematic Universe)
- Wild C.A.T.s (1994)
- Winx Club: From season 4 onward and in the World of Winx Spin-Off, the Winx become Earth's fairy superheroes.
- W.I.T.C.H.
- Wolverine and the X-Men (2009)
- WordGirl
- X-Men: The Animated Series
- X-Men: Evolution
- Young Justice (2010)
- Zeroman
- Zevo-3
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