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the only series that I can think of at the moment that even relatively match that description is Growing Up Creepie as the other person said, Creepschool (about kids who go to a paranormal boarding school), Monster Allergy (Male protag w/ Blue hair, deals with monsters), or Juniper Lee (also dealing with paranormal stuff)
Wow all great suggestions, thanks. I definitely think it was earlier than Growing Up Creepie although the animation was pretty similar in style iirc. The protagonist was definitely a tall, teenage girl. The episode I saw was kind of centred around the end of the world (or the destruction of the school anyway) and a group of "popular girls" just didn't notice.
I can't believe that I can't find this, it's almost like it was just erased off the earth haha.
Edited by ProfessionalTofukemerritt, Black Hole High, to use it's alternate title, is live action, and therefore cannot be what Professional Tofu is looking for.

Hi, I've been trying for years to find a cartoon which I saw once as a child (late 90s or early 2000s). It either was cancelled after the pilot or a once-off as I never saw it again. It was set in a school which experienced some kind of paranormal activity and the protagonist was a new, teenage student (might have had blue hair). As far I remember, the other students considered the paranormal things normal. She makes two friends (a girl and boy?).
The only scene I remember was when the two girls go to the bathroom after experiencing something strange. The dialogue was something like: "I'm sweating after that." "Hey, can I borrow your deodorant?" "Isn't that kind of gross?" "It's okay, I'm only using it on my lip!"
The art style was somehow really unique. If someone has any idea, let me know as my searching yields no results! Thanks in advance!