When you find yourself trying to remember a show (or any works) that's on the tip of your tongue but just out of reach, come here - the collective brain of the TVTropes community can probably help. Post all the details you can remember (examples help). If you're looking for a trope, head over to Trope Finder. Have general questions about tropes? Visit Ask The Tropers!
http://madcoversite.com/mad427.html
lists what's in #427. You can search the site and see if anything rings a bell.
No, I do not think it is #427. It features another baby with a bloated diaper on the MAD Departments page, and the baby was similarly colorized, also had a smile, and had a similar haircut, the baby was smaller and was sitting down. Also as I said, it is from a more current MAD Magazine, 2007 to current, but I think from 2009-10. Does anyone know this? I wish there was some site, where you can view all MAD Magazines (from front cover to the pages to the back cover).
While it's not the only possibility, it's likely that the baby is from the recurring strip "Monroe." This would have been during the colorized run of the strips, so did the baby have a similar style to this [1]
◊?
Also, the superhero, do you remember if he was a generic one or a specific hero? That could narrow it down.
Could this have been a MAD Kids or Mad Classics issue too?
I do not think it is from "Monroe." The baby's head was not entirely bald, but it had a bald haircut, there was a short amount of light brown hair on its head. Unfortunately, it was the first picture I noticed on the page that really stuck out to me, I cannot remember the rest of the pictures that much, but if there was a superhero, which I have a gut feeling there was, it was probably a generic hero. I do not think it was a MAD Classics issue or a MAD kids, but could have been. I think it was a flashback MAD issue. As I said, the baby looks a lot like the baby from the departments page of MAD Magazine #427, but was much smaller in illustration and it was sitting down. Maybe my mind is playing tricks on me, but I do not think it was a 2003 issue. I cannot remember for sure when I read it, but I know for sure, if it was not #427, it was not from 2006 or earlier. I have a MAD Magazine CD-Rom, in which you can view all the MAD magazines from late to 2006 to way back when, but unfortunately it does not include 2007 to present.

I was visiting my local library around 2007-2009, and I read a MAD Magazine. Unfortunately, I cannot remember the cover (front or back) or most of the magazine, but I remember the departments page. I saw images, such as a colored illustration of a baby sitting down wearing a bloated diaper, a superhero, a small garbage can (I think), someone vomiting, and a piece of talking pizza (maybe), and I think there were toys designed for kids in the magazine. I do not think this is #427, could be, but my local library told me they mostly store current magazines, and there is no way they can track back to their prior magazines. Anyway, I know this is not much to go on, but can anyone please help? This is driving me nuts, and I already emailed the official MAD Magazine site, and my local library, but no success. Thanks in advance.