Memetic Mutation: "There's a mushroom on your shirt." "Oh, I'm a failure!"note This scene became popular on Vine for how absurd Francine's reaction seems out of context; in context, she broke her Yom Kippur fast by having a slice of pizza.
"Never, Never, Never":
Karmic Overkill: As much of a Bratty Half-Pint that D.W. can be, many fans viewed the Tibble twins completely ruining her toys with no remorse to be needlessly mean-spirited.