One skit featured a fake commercial for a new squirt gun that shot out boogers and mucus instead of water. While it didn't use actual body fluids, there was a Super Soaker variant called the "Oozeinator" that shot out water, as well as a viscous fluid called "Bio-Ooze"; it was recalled because people complained that it looked like the kids were giving each other moneyshotsnote In the pornographic sense.. This unfortunate comparison appears to have been referenced at the end of the skit when the commercial advertised another product called the "Cum Bomb".
The Hitler rap makes references to committing 'lyrical genocide', how the SS now stands for 'super smooth', burning CD's instead of people, drinking with 'his bitch Anne Frank' and being on Schindler's List.
Fridge Horror: Parodied. A doe is presenting herself to a trio of hunters, and tries to seduce them by wearing a lacy bra. One of them notes, "It's funny, because it means at some point, she killed a woman!"
Harsher in Hindsight: Quite a few sketches have become this after Trevor Moore's untimely death.
In the second episode of the final season the "Old Folks Home" sketch includes a lyric saying to spend time with your loved ones because you don't know how long you're going to have with them. After Trevor's sudden death in August 2021, it almost feels like he's singing about himself.
The same can be said about the auto-erotic asphyxiation skit. Looks like God is not giving him a third chance.
Likewise for the "Home Alone" parody in which Trevor sets up numerous traps only to kill himself while on the phone with 911. Only his real cause of death was accident related as opposed to suicide related.
The "Russian Roulette" skit has Trevor be the one that organizes the fatal game that ultimately results in Sam's, Timmy's and his own deaths. Take a wild guess who was the first to die in real life.
The "Whiskey" sketch is really uncomfortable to watch since Trevor Moore died after a fall while he was drunk.
This sketch about Star Wars Episode VII after it was announced that a new trilogy was being made. The sketch even predicted that there would be another Death Star in the movie (well, actually the Starkiller Base but close enough).
The season 5 episode about the Nerf Nuke? It's a real Nerf weapon now.
Magnificent Bastard: "Sniper Business": Mr. Welburn is a hilariously ruthless, business minded corporate overlord. When his rivals at Bergman-Sachs hire a sniper to kill him, Welburn uses the situation as an opportunity to espouse his business ideals and rhetoric to his employee Jenkins while deftly outmaneuvering the sniper. Sacrificing a hapless intern to distract and kill the sniper, Welburn then uses more weaponry and stoicism in the face of danger to negotiate a truce with his rivals, considering the entire ordeal just another part of running a business and having no hard feelings about the situation.
Unintentional Period Piece: The "Moon Bear" sketch has a brief exchange where a reporter points out that there are nine known planets in the Solar System. Since the initial airing, that number has gone down to eight thanks to Pluto being redesignated.
. For a series that featured a rapping Hitler and Kid Beer, this was out of left field even by those standards. That said, its strangeness made it one of the most popular sketches among the fanbase.