Ass Pull: The final episode can come off as this. After building up to a dramatic showdown with Dark Surfer, he's defeated and then shown to be Disc-One Final Boss. The heroes find Dr. Doom, having claimed the Infinity Sword/Stones, and the Squad fight him... only for the stones to shatter and conveniently restore everything to normal.
Awesome Music: Fans and non-fans can agree that the tracks are pretty catchy, especially the theme song.
Big-Lipped Alligator Moment: Pretty regularly. For instance, when Dr Strange was reading everyone's minds, Thor is wondering if his tights make his thighs look big.
Fridge Brilliance: At one point, most of the squad has to either serve jail time or pay an enormous fine. Everyone is shown in jail, except for Iron Man who, as one of the richest men in the Marvel universe, could pay his fine with ease.
Wolverine's list of people he's teamed up with includes the Easter Bunny. In the fall of 2012, a movie was released where Hugh Jackman voiced the Easter Bunny.
Captain America is Demoted to Extra, while Falcon was made into a series regular. In a post-Avengers world, fat chance of something like that happening again.
One episode has Doctor Strange go insane after a fractal of the Infinity Sword (actually a long-lost Infinity Gem) gets embedded into the Eye of Agamotto. In his solo movie, it is revealeded that the Eye of Agamotto harnesses an actual Infinity Stone, but Strange is able to control it.
The season 2 opening shows Thor and Hulk during the line "While they may not get along but they're always fighting strong now". Then comes the release of Thor: Ragnarok several years later and that film is the embodiment of these lyrics.
The season 2 theme has the lyrics "Even Thanos ends in tears, when Iron Man joins the fight". Indeed, it is Iron Man who brings about Thanos' doom in Avengers: Endgame. Also counts as Harsher in Hindsight since Iron Man also dies killing Thanos.
One of the Hulk transformation Couch Gags had the Hulk change so that he was drawn in the style of The Simpsons, a Fox property. It's more hilarious in light of Disney acquiring most of Fox's assets on March 20, 2019.
The concept of a Dark Silver Surfer would come to life years later in 2019 with the Black Surfer, only this time the Surfer remains a hero as opposed to the villain he is in the show.
Likewise, Thanos and the Infinity Gauntlet being an arc of the show soon enough prompted jokes about how Avengers: Infinity War and Avengers: Endgame (both of which would be released about a decade after the conclusion of this show) looks great.
Retroactive Recognition: Reptil is Pit. And speaking of Kid Icarus, in one episode, S. Scott Bullock provides the voice of the Red King, using the exact voice he'd later use for Hades.
Spiritual Successor: The whole franchise is most likely to have been—at least partially—inspired by Mini Marvels. With that said, how much of a "successor" the series may be is debatable since Mini Marvels is still ongoing. Plus, Chris Giarrusso's style and approach are different, in that he depicts the heroes and villains (most of them, anyway) as kids rather than just Super-Deformed grown-ups.
Squick: Whilst having his suit melted, the heroes jokingly ponder what's underneath:
Of course, all his metal was melting... You probably don't want to think too hard about that.
Vindicated by History: Though this show was inevitably overlooked, especially in comparison to other comedy spinoffs of action franchises, the show is actually held in higher regard than most, with a good portion agreeing that it is a surprisingly decent Affectionate Parody despite the Merchandise-Driven nature, and mostly has a lot of respect for the audience, whether older Marvel fans or (relative) newcomers.