- Big-Lipped Alligator Moment: The Musical Episode "Good Neighbor Ed" features a very brief and completely irrelevant song by Miss Malone (while she's working her waitress job) about how she's apparently one of the few actresses who can also swim.
- Bizarro Episode: While all of them have their moments of being weird, the weirdest episode of the show is "Driver Ed," in which Grimley teaches Miss Malone how to drive and the duo drive into a tunnel as a train is coming down the tracks. They come out of the tunnel, seemingly okay...until they discover that they didn't survive the crash and now they're ghosts. For the rest of the episode, they haunt Mr. Freebus, telling him to get their affairs in order (such as take care of Wendell, clean Moby's fish tank, cancel all of Miss Malone's acting and improv classes, etc) to the point that he gets sent to a mental hospital...then Mr. Freebus wakes up.
- Dream Team: Hanna-Barbara animating half the cast of SCTV. Also, Martin Short and Jonathan Winters in the same show.
- Ear Worm: The theme song is REALLY catchy!
- So Okay, It's Average: It's not as lively as the SCTV or SNL take on Grimley (SCTV had Grimley as a TV and movie star while SNL had him as a [relatively] normal person living in an apartment and encountering strange events and people), but it definitely has its moments.
- Suspiciously Similar Song: Seeing as the show was already trying to capitalize on the popularity of Pee-wee Herman, it's no surprised that the theme song sounds a lot like the music from the breakfast machine scene in Pee-wee's Big Adventure.
- Uncanny Valley: Seeing as he was drawn to look like an actual person, Ed sticks out like a sore thumb amongst the more exaggerated character designs.
- Vindicated by Reruns: Most people who have seen the show remember it more when Cartoon Network and Boomerang aired it in the 1990s rather than NBC in the late 1980s.
YMMV / The Completely Mental Misadventures of Ed Grimley