- Character Rerailment: Before Epic Mickey and Mickey Mouse (2013), this short attempted to bring back Mickey's much more adventurous side, or at least reconcile the current Mickey's characterization with that of his old one.
- Ensemble Dark Horse: Dr. Frankenollie is a very memorable character, despite his lack of screentime.
- Hilarious in Hindsight: Julius, as a Frankenstein, slobbering Mickey, does bear a resemblance to Sonic The Werehog.
- Signature Scene: When Julius' brain is put into Mickey's body, we are treated to one of the creepiest depictions of Mickey Mouse, and easily the most iconic.
- They Wasted a Perfectly Good Character: Dr. Frankenollie—he manages to maintain that delicate balance of creepily sinister and comically entertaining almost flawlessly, something even particularly famous villains struggle with sometimes, and has the great voice performance of Kelsey Grammer, so of course he's gonna be the Big Bad of the short, right? WRONG! Instead, he gets brutally killed off after appearing in only one scene(he was supposed to have more screen-time but Executive Meddling from Disney stopped that from happening). He did reappear in the CyberNettiquette Comix, though.
- What Do You Mean, It's for Kids?: An animated short filled to the brim with disturbing imagery and brutal, onscreen death, all featuring a classic children's character! And its rated G!
YMMV / Runaway Brain