- Memetic Mutation: Fans often claim the show is "bad for your heart" and can induce heart attacks.
- Moe:
- Tsumiki. Good lord, Tsumiki.
- Taken up to eleven in the "Acchi Kocchi Kindergarten" segments.
- And then, there's Hime, who is just... Yeah, you get the idea.
- And just when you thought couldn't exceed those levels, say hello to Cute Fairy and Tsumikitty◊!
- Ship Mates: Some fans ship Mayoi and Sakaki as a foil pairing to Tsumiki and Io.
- What Do You Mean, It's Not for Little Girls?: It is a very cutesy, relatively clean (with a few dirty jokes here and there) slice of life show about a schoolgirl's first crush. Despite this, its manga runs in a seinen magazine, and the anime aired at 1:25 a.m. on TBS.
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