Complete Monster: Painkiller Jane vs. The Darkness: Stripper, by Garth Ennis et al.: "The Stripper" is a sadistic Serial Killer who loves to kill her victims by removing their skin while they are still alive. Having already managed to kill this way around a dozen of people, including her parents, the Stripper finds herself a new victim in lowly conman Terrence J. Flannery. Initially saving him from a mob of angry ninjas, she drives him to her house. As Jackie Estacado and Jane managed to track down Terrence in her house, they find him alive with most of his skin removed. The Stripper attacks them, intending to skin them alive as well.
Series:
Narm: The gratuitous slow-motion sequence (especially the part where Jane yells, "CONNOR!") at the beginning of "The Healer."
A lot of Jane's injuries, like when she shoots herself through the palm in "Higher Court" or when we got lovely red-tinted internal shots of the damage caused by her breaking her own wrist to get out of a pair of handcuffs in "Portraits of Lauren Gray."
Jane (who is herself visibly disgusted) cutting the eyeball out of a corpse in order to use it on a retinal scanner in "What Lies Beneath."
The heart and brain removals and the maggot-infested wound from "Reflections."
Unintentionally Unsympathetic: Phyllis Carson/Wanda Morton from "Portraits of Lauren Gray." While Jane (and, by extension, the show) clearly wants the viewer to pity and have at least some sympathy for her, her weak Freudian Excuse, selfish motive, bitchy demeanor, blase attitude towards her crimes, halfhearted justifications for them, and insincere-feeling claims of reluctance and remorse make that difficult, and cause her agonizing demise to come off as more of a Karmic Death than an instance of Alas, Poor Villain.
