- Adaptation Displacement: When this page was started, there were more entries on this wiki for the game than the actual show. Likely due to the Keep Circulating the Tapes in the Trivia tab.
- Alternate Character Interpretation: Many fans think Ned has a condition when you can only have nightmares instead of dreams.
- Not to mention a sleep condition such as Narcolepsy, and possibly even an Anxiety Disorder due to how nervous and high strung he is most of the time.
- Awesome Moment: When the substitute parents chew out the principal, saying their son would never do such a bad thing he has been accused of.
- Awesome Music: The hauntingly melodious main theme.
- Big-Lipped Alligator Moment: The wrong numbers made while in the principal's office."Love ya, baby! Childrens' talent agency!"
- For a split second during the Bathroom to Medical nightmare cutscene we see a group of unfamiliar characters known as "Csence".
- Catharsis Factor: Gaining the ability to fight back against the doctor in the mouth section of the medical nightmare and seeing him fall on a bunch of needles is very satisfying after all the trouble he has given you.
- Crack Pairing: In one of the episodes, the queen ant in Ned's antfarm falls in love with his Dad. Dad turns her down solely because he's already married.
- Crosses the Line Twice: Spinning on a giant wheel, a freak, unnecessary, abominable, monster organ transplant surgery, accompanied by horrified screams.
- Possibly subverted when it looks like they are actually just stuffing the organs down his shirt instead of putting them inside of him... Which is still really gross, anyhow...
- Goddamned Bats: The game has a number of these, mostly in the Graveyard Nightmare.
- Hilarious in Hindsight: Ned's dog form from "Ned's Life as a Dog" looks an awful lot like Brian Griffin.
- Nausea Fuel: The whole Mouth stage is beyond nasty.
- Squick: A lot. The Plaque Monsters in the Mouth pulsate and explode messily when hit.
- "My head is ready to burst all over!"
- Grenny, Cyco, and Truddy; the toilet-clog monsters. Yes, you read that right.
- They Wasted a Perfectly Good Character: The Shadows are interesting, mysterious characters, but they only have a few lines of dialogue each (most of which you can go through the entire game without hearing), they only speak in the hub world and during the intro and ending sequences, and they're defeated indirectly without directly fighting or confronting any of them.
- The Woobie: Ned, and the little girl from in the mausoleum.
- What Do You Mean, It's for Kids?: Ask most anyone who knows about this game and you'll probably bound to hear something like "Oh, man! That game gave me so many nightmares as a kid."
- What Do You Mean It Wasnt Made On Drugs: A majority of the game.
- I'm Your Uvula Song: The Uvula Song. An over-sized, talking uvula wearing a suit and singing swing music to some martini-sipping, rotted teeth in a lounge inside of a giant mouth? Seems legit.
- Some gamers joke about how the teacher from the Teacher Song had crack before making the song.
- Writer-Induced Fanon: Sally the little girl is actually Ned's mom as a child.
YMMV / Nightmare Ned