- Awesome Music: The music for the Wily levels is easily one of the most climactic and epic tunes in the series history. The Wily boss theme similarly has an awesome feel to it.
- Even Better Sequel: To the previous three games, though most fans agree that the following game just edges for the title of best in the Game Boy subseries.
- Older Than They Think:
- The ability to buy upgrades originated in this game, and not Mega Man 7 as many assume, albeit this game (and Mega Man V) has a different way of paying for upgrades, using P-Chips instead of bolts.
- This is also the first game in the Mega Man franchise to have a second level select theme (albeit it's just the first level select theme in a higher key), beating Mega Man X to the punch by a few months.
- Conversely, the super pellet, which in this game is occasionally supplied by Proto Man, actually first appeared all the way back in Mega Man (though there was only one in the entire game, and it looked completely different to how it does here).
- Sequel Difficulty Drop: Compared to the previous game, the enemy placement is a lot fairer and the levels are generally less troublesome. Additionally, the Item Replicator allows Item Farming to mitigate most of the games challenge.
- That One Boss: Bright Man is back to bring the pain. Unlike his NES counterpart that only used his Flash Stopper when at a certain amount of health, Game Boy Bright Man can use the Flash Stopper anytime he wants. Beating Bright Man this time around all depends on whether or not he decides to be obnoxious. On the plus side, his weakness- the Rain Flush- hits multiple times per use and ultimately kills him faster.
YMMV / Mega Man IV