In "Superior Smash Siblings", excessive focus was put on Bowser as if his inclusion was new and exciting.
When Super Smash Bros. for Wii U / 3DS was actually released, Bowser was one of the most commonly used characters at first, widely believed to be top-tier. Though he was later found to be counterable, his reputation still lingers.
The first line of "John Goodman Breaks", a Roseanne poop, is "Quiet, you'll attract niggers." Years later, a successful revival of the show was quickly cancelled after Roseanne Barr posted some damningly racist tweets against Valerie Jarrett.
"Emperor of the Plateau", a King of the Hill YTP, has the line "I can't say the word 'sus' without someone giggling." At the time, mirroring a word to turn it into a nonsense palindrome like "sus" was a common thing to do in YTP, but as many comments on the video point out, this line took on a completely different meaning after Among Us became a major source of memes, with the word "sus" (short for "suspicious") in particular integrating itself into the internet's lexicon. A further evolution of the meme had people overreact to anything that vaguely reminds them of Among Us, which means that, in some circles, you could indeed make someone giggle simply by saying the word "sus".
It shouldn't be possible to have a rash from getting fucked by your grandfather as a kid, apparently.