Even if Aresia's plague failed to wipe out the total male population, it did not go without casualties. Elderly men, young children, and others with weaker constitutions all died before the cure could be administered. It's later stated that young girls and women also died as well, incidentally as a result of the men falling ill and dying around them.
It's also mentioned that Aresia's dream of a female utopia would never have happened, as not every woman hates men, let alone enough to want all men dead. More than a small percentage of the world's female population wants her dead.
If Aresia had not been taken back to the island, she would have been executed for terrorism.
After it has become public that Aresia has escaped despite the promises the Amazons made, and Diana spells out the extent of their failings with Aresia and unwitting complicity, Hippolyta realizes that Themyscira can no longer stay out of the affairs of the world if it wants to keep a sliver of goodwill and independence. Thus she names Diana to be ambassador to try and fix this disaster.
This also extends to the Straw Hats and the heists. Unlike Gaia which has the strong doing what they want with little to no consequence, their robberies of corporations and takedowns of criminal empires have left such businesses forced to shut down, left people unemployed, and power vacuums appearing everywhere. It's one of the major reasons why they are on the JL's radar.
Fridge Horror: Aresia believes that her plague would cause men and only men to die. An Amazon points out that plenty of women and young girls also died. Not because the plague mutated to effect women, but because they were in vehicles being driven by men or were being taken care of by men at the time.
In one of the omakes, Buggy the Clown was compared to the Joker, which from his perspective, it was a codename of Donquixote Doflamingo, and he accepts it as a compliment. In One Piece (2023), Buggy is portrayed as Practically Joker.
