- Hilarious in Hindsight: The very same episode that tells us homophobia is wrong has a plot which ends with Doogie being informed by his girlfriend that "[his] charm lies in not being one of the guys."
- Also Doogie attempting to drink scotch and smoke a cigar, but getting ill. Years and years later on How I Met Your Mother, he's playing Barney Stinson, who smokes cigars and is a functional alcoholic.
- Memetic Mutation: To this day, any person who is established and successful in a career at a much younger age than is typical is referred to as a "Doogie Howser-type".
- Retroactive Recognition: That reporter from Love Means Constantly Having to Say You're Sorry? That's Otacon.
YMMV / Doogie Howser, M.D.