Keith (the Cleavage Crab) is either funny or annoying and promotes sexual harassment.
Bee. She's either quirky and funny or annoying.
Broken Base: The decision to release the season finale along with the rest of the show exclusively on VRVnote An app by the same company that hosts Crunchyroll has split fans, with some fans understanding that Youtube ad revenue really can't pay for high quality animations while others argue that the whole point of the kickstarter was so the show could be made without needing a paid subscription.
The discourse about this subsided when the rest of the series was uploaded onto youtube. However now fans are arguing over the lack of communication between the show creators and fans after the show missed its original season two release date. It turns out the studio had finished the show in December and were looking for a new streaming service to host it, but the fans were upset at not being told this information directly. Instead they had to call the studio themselves and ask for the reason behind its delay.
Ho Yay: Puppycat's behavior indicates he may have a crush on Pretty Patrick and Wesley Wizard.
Deckard and the Cooking Prince also gave off this vibe to many viewers, particularly the latters interest in the former.
Fridge Horror: Wallace's fate raises some scary questions. It seemed Puppycat had met him before, so it's probably safe to assume that the information Puppycat had on him was accurate and that he was in fact an "ordinary" fish previously. He appears to have been possessed, but did he die during the process, or was he alive but unable to do anything until the monster popped out of him? Or was he replaced and is dead/trapped somewhere? What will happen when his mother comes home and finds him gone?
Alternatively, he may have been a monster all along, and was simply biding his time until Puppycat revealed what he knew about the space outlaw. Mitigates the above Fridge Horror somewhat, but replaces it with a different kind of horror.
"Donut" brings one up in regards to Bee and the revelation that some parts of her are robotic. If she wasn't born that way...what exactly happened to her?
Ship-to-Ship Combat: Bee/Deckard was pretty much the OTP of the first season, but Lazy In Space introduces the Bee/Crispin and Deckard/Cooking Prince, causing this in some parts of the fandom.
Squick: Bee biting the monster's tongue, which turns out to be entirely effective, causing blood to squirt everywhere.
They Changed It, Now It Sucks!: Many fans were disappointed by the changes in art style and characterization between the pilot and the actual show. (For example, Bee having her Manchild tendencies turned up.)
The story of the space outlaw and the space princess told by Puppycat. Especially with the implication that it's his backstory.
The finale of the first series. Cardamom's mother doesn't wake up from her coma (though she does start crying), Deckard goes off to the academy without directly saying goodbye to Bee, and Puppycat and the audience learn Bee is at least partly robotic just in time for the show to end. It isn't all sad, but it does end on a very bittersweet note.
What Do You Mean, It's Not for Kids?: Bee and Puppycat airs on Frederator Studios' Cartoon Hangover, which is an outlet for adult animation, and despite the pretty colors and perky protagonist, Bee and Puppycat isn't targeted towards kids. It is relatively downplayed in that there isn't really much in the show that's objectionable in the first place (especially compared to sister show Bravest Warriors)—with really the only glaring "naughty" stuff present being some mild language, an innuendo here and there, and a brief splash of blood in the final episode—but the recurring theme of settling into adulthood do resonate more seriously with the target demographic.
Moully the Giant Baker in the last episode was a somewhat clumsy, but kind person. He ends up getting pulled into the Wishing Hole for no reason and it's unclear if he was taken to another dimension or outright killed. His last words to Bee imply that not a lot of people have been nice to him either.