This becomes more difficult when Twins Fungus and Maggot decide to attend human school. Now, with help from their new friend Sam, the twins have to try to keep a low profile which isn't always so easy.
Zombie Hotel features examples of the following tropes:
- Abhorrent Admirer: Fungus gets one in the form a goth girl. But he ultimately learns to appreciate her.
- All-Ghouls School: Inverted, zombies Fungus and Maggot have to attend a human school.
- Brainwashed and Crazy: One episode featured a magic potion that made everyone exposed to it act extremely happy and goofy.
- Friendly Zombie: Maggot and Fungus are pretty much indistinguishable from normal humans in terms of behavior. They have loving parents, attend a human school, sleep in proper beds, and are best friends with a human named Sam.
- The Masquerade: Fungus and Maggot must be careful not to reveal themselves to their classmates, except Sam.
- Monster Mash: A hotel run by zombies, with a mummy, ghost, and old British adventurer with a Shrunken Head as well.
- Muggle Best Friend: Sam to Fungus and Maggot. He is also their Secret Keeper.