Off-screen, the Punisher targeted The Big Hero Six in this story. Guesses as to how he killed them
- Baymax: EMP.
- Honey Lemon: Got strangled and hanged with her own purse handle.
- Wasabi No-Ginger: Stabbed to death during a fight involving his Qi blades Vs. some tech Punisher used to counter them.
- Hiro: Shot to death with some kind of gun meant to counter his battle-suit and gadgets.
- Fredzilla: Like how Banner was killed, he was shot in his human form.
- Go-Go Tomago: Punisher ran her over with a high-tech vehicle meant to keep up with her battle-suit's speed.
Guesses to how the Punisher took out the Power Pack off-screen.
- Katie: Hung from a tree with a skipping rope.
- Jack: Grabbed by Frank and thrown in front of a moving car on a road during rush hour.
- Julie: Frank fed her poisoned cotton candy.
- Alex: Frank grabbed a broken fence post and rammed it through his heart.
The Punisher was somehow brought back post-story and went on to avenge Matt, now blaming the remaining super-villains for driving him insane and leading him to unknowingly kill Matt
Alternatively, after being somehow resurrected, Punisher relaxes his anti-superhero code and only goes after superheroes who are above street-level in terms of abilities.
Alternatively, after being somehow resurrected, Earth is invaded by one of the myriad of Scary Dogmatic Aliens that populate the Marvel Universe and Frank realizes it's all his fault that his planet is about to be conquered/destroyed.
Alternatively, the world gets invaded by magical villains.
