Jake is trans
When his mother prepared a double bed
for him and Jeanette, they were embarrassed despite being a couple and Jake said "Do you think it's uncomfortable because I was a-" before being interrupted by RAM. And earlier, we saw that he had no problem wearing RAM's women's clothes.Jack's time in jail also showed that in-universe, a wig was enough for robots to mistake him for his sister.
- In the Pride month special Jake's clothes turn into an asexual flag, which could explain the bed sharing awkwardness (asexuals are not necessary aromantic).
Ali is a normal cat
Ali is just an ordinary cat from a universe closer to the real world, but since cats in the universe are anthropomorphic the crew treat it like some weird alien creature.R.A.M.'s dream was prophetic.
Jackie did claim that aliens were real when talking about the time she hacked the Octagon, after all. was prophetic.