- Both are named the same. Pretty obvious.
- Both are mostly comprised of Latin Americans.
Though they are two vastly different groups and have vastly different insignias, it's fairly easy to draw the connections. Though they were bruised and battered at the hands of Nathan Zachary and the Fortune Hunters, the gang survived. After two Die Spinne attacks on Chicago, the United States started coming back together to face off against Herr Hitler and The Wehrmacht. This was the perfect time for Los Muertos to rebrand itself. They moved westward, into the Nation of Hollywood, and became a drug cartel. Once everything settled down, they got some connections in South America and started selling drugs on the streets. The city they operated in became known as Paradise City and overrun with street racers. They took advantage of the racers and became one of the largest criminal forces in the city. They took control of the area known as Palm Bay Heights, the residential/tourist area. When Paradise City detached from the mainland and became Pacific City, the area they controlled became known as La Mugre, "The Dirt".
- MS does own Halo, so this could be true. Plus, do we have proof this is on Earth? Humanity had HUNDREDS of planets. This could be a Rebel planet.
- Furthermore, the mutant freak outbreak seen in Crackdown 2 could be seen as a localized Flood infestation. Being a Rebel planet, Pacific City's government wouldn't be able to call upon the UNSC for help containing it. So, the Agency's superpowered Agents would have to step in to protect the city again. It could even be that the Agency knew that the Flood were coming, and the 'Crackdown' seen in the first game was simply a test of the Agent program's capability of fighting off large numbers of attackers at once. Crackdown 2 gets to see the fruits of those labors.
- The original purpose of the SPARTAN-I and SPARTAN-II projects was to supress rebellions; the end result of the SPARTAN-II Project just nicely dovetailed with the Scary Dogmatic Aliens, which mirrors the fact that the Peacekeepers are the harbingers of a police state. As for the infected being floodified, I'm going to argue that they were a result of a different SPARTAN Project (SPARTAN-Negative I?).
- Seeing as Crackdown 1's mutants are minions of the same scientist responsible for the Agents, this isn't too farfetched. These mutants are possibly 'washouts' of the SPARTAN-Zero program, in much the same vein as the washouts of the Fall of Reach novel.
Related to the above WMG. At the end of the game the Agent is an absolute hulk who can clear buildings in a single leap. Qualities similar to those possessed by the Blackwatch Supersoldiers, who are the only human (well, humanoid) mooks who can rival Alex Mercer's abilities. Like the Supersoldier, though, the Agent still isn't quite a match for Mercer. He can't run along vertical surfaces, for one thing...
- Even more so in 2. The Freaks are humans mutated by a virus, who slowly progress from basically zombies to giant apelike monstrosities covered in pus. Maybe Czernenko was experimenting with a different strain of Blacklight (ability to spew acid, but vulnerable to sunlight)?
- It's just something about the way he comments on how cools things are, how eager he is for you to chase renegade spheres, how gleeful he sounds when you blow people up or catch on fire, he sounds like a kid trying to impress someone with all his cool stuff and encouraging you to play with them.