The weirdness surrounding the dandelions may also explain Rosebud and the jackabasselope puppies.
But this is completely explained. In Tales Too Ticklish to Tell, we see a man convicted of murdering the entire Moose Lodge. Milo's grandfather was a member of the Moose Lodge. Hence, Milo's grandfather was murdered.
- That's... morbid. And brilliant.
The other disappeared characters, however, may have had more mundane fates, as happens in everyday life:
- Yaz Pistachio went away to college.
- Rabies got loose (or got bored) and ran off.
- Blondie and Alphonso moved to other towns with their respective sets of parents.
- Limekiller was arrested, and/or he ran off after his comments in the Meadow Party Election. Coming off as a sexist and a racist and calling a disabled person a cripple (as well as entirely ignoring the animal portion of the party, which made up half of the party).
- Otis Oracle moved off to Lynchburg, Virginia, to join the Moral Majority. And when the main chapter fell, he possibly joined the Westburro Baptist Church.
- Tess Turbo fell out of pop cultural relevance. And, given her thoughts during her first appearance, went on to have a career revival after a successful autobiography, this time in the more soulful stuff.
- Milo went off in search of America (think about it: he was on a bus in the very last Outland comic).
- In between Outland and Opus (or even between Bloom County and Outland), child prodigy Oliver was accepted to some prestigious academy for the gifted.
- Around the time of the Major's death, Bess Bloom also died. The town let Milo keep the boarding house instead of sending him to a foster home, since Milo seemed to be running the boarding house later on.
- Pops Paplov and Ruby Tucker moved out, possibly together.
- Lola Limekiller left to find her son.
- Also, Oliver is Marcus. Not only are they both black nerds, they have the same last name: Jones.
- The reason Milo was on a bus in the 2nd-to-last Outland strip was because he was moving to Illinois, setting up Foxtrot.
- And the Banana Jr. 6000 was an early version of the iFruit.