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Nurse Love Syndrome is a Yuri Genre Visual Novel developed by Kogado Studio and published by Degica. It was released for the PlayStation Portable on September 29, 2011 in Japan. It got an expanded version titled RE:Therapy for the PlayStation Portable and PC on June 28, 2012, which was later remastered and released worldwide on April 18, 2019 on the Play Station Vita and PC through Steam and again on December 26, 2019 for Nintendo Switch. A physical release is expected in 2020 from Limited Run Games.

Kaori Sawai is the newest member of the Yurigahama Hospital staff. As a survivor of a deadly accident from her childhood, Kaori is determined to become a nurse and help others like she herself was helped. At Yurigahama Hospital, she will encounter all sorts of characters: her upperclassman Nagisa Fujisawa, the energetic Yasuko Yamanouchi, the strict head nurse Hatsumi Otsuka, the barb-tongued patient Sayuri Sakai, the cheerful high school student Ami Asada, and the enigmatic Mayuki Wakamoto.

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Nurse Love Syndrome has a sequel called Nurse Love Addiction, which takes place in the same world but has a new cast of characters and its own self-contained story.


Nurse Love Syndrome contains examples of:

  • Abusive Parents:
    • In childhood, Sayuri's mother was emotionally distant and just barely gave her enough to survive which is why she developed her ice queen personality. During the main story, Sayuri's mother visits to simply make sure Sayuri gets her inheritance after she's discharged on the condition she severs all ties with the family.
    • Part of Yamanouchi's backstory of neglectful parents.
  • A-Cup Angst: None of the characters actually suffer this, but Yamanouchi loves to roleplay them like they do.
  • Aloof Dark-Haired Girl: Sayuri starts off incredibly harsh and hateful towards Kaori, rejecting attempts to befriend her. She slowly becomes friendlier over the course of the story.
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  • Apologises a Lot: Kaori, given she's a new nurse she often has to apologize for making frequent mistakes. Sometimes she just apologizes because she doesn't know what else to say. Sometimes Sayuri calls her out on this trait.
  • Bonding Through Shared Earbuds: As Kaori grows closer to Mayuki, she's offered this.
  • Burial at Sea: Sayuri's Bad Ending results in her body rejecting her bone marrow transplant. Kaori picks up her lifeless body and walks out into the ocean with her to lay her to rest.
  • Cathartic Exhalation: To calm herself down, Kaori often does this.
  • Clingy Jealous Girl: Nagisa's bad ending. Nagisa keeps Kaori chained up in an apartment somewhere so that nobody else can have her. Even in her normal route she falls into this as she was intentionally frighting Kaori with mysterious calls and threatening emails to make her more dependent on her.
  • Cloudcuckoolander: Chief Hatsumi Otsuka is a brilliant nurse but also known to be a little spacey. She forgot to mention to Kaori the nurses have a designated room to store and change into their uniforms.
  • Cue the Sun: A somber example happens during Sayuri's bad ending as she succombs to fever.
  • Da Chief: Hatsumi runs a tight ship and sometimes comes down a little hard on her nurses, but is still a kind person willing to do what's best for the patients and nurses in her care.
  • Dark and Troubled Past: Yamanouchi reveals to Kaori about her troubled home life growing up and Sayuri's mother was abusive while growing up and into her adulthood as well.
  • Defrosting Ice Queen: Sayuri initially treats Kaori extremely venomously, constantly belittling her for every mistake she makes. On her route, she starts becoming friendlier and eventually pulls a complete 180, becoming Kaori's very doting girlfriend.
  • Dirty Old Man: Yamanouchi has all the traits, despite being a woman who probably hasn't even hit 30 yet.
  • Do Not Call Me "Paul": Yamanouchi does not like being called Yasuko. Turns out it was the name of an ex-girlfriend of her father.
  • Driven to Suicide: In Nagisa's route, the stress she's under causes her to threaten to jump, or to go through with it if the player doesn't stop her. However, she still survives the fall.
    • Part of Yamanouchi's backstory reveals her mother hung herself after being hounded by debt collectors.
  • Embarrassing Nickname: Yamanouchi often calls Nagisa "Horseysawa" because of Nagisa's tendencies to make long exasperated sounds.
  • Genki Girl: Yamanouchi.
  • Healing Hands: Kaori's touch can soothe the pain of other people, to the point where quite a few are convinced she has actual healing hands, though Kaori thinks they're just experiencing the placebo effect. Kaori can do this because she has Hazuki's organs implanted in her, since Hazuki herself possessed strange powers when she was still alive.
  • Hard-Drinking Party Girl: Nagisa loves to down several beers in an evening. Though Kaori can throw a few back herself.
  • Heroic B So D: Kaori especially suffers these depending on the story route. In the main story, strange mysterious phone calls trigger her past trauma about her car accident and make her fear for her life. In some routes, seeing the first patient in her ward die proves to be difficult for her to cope with at first.
    • Nagisa in her route, having a bad working environment after transferring to surgery.
  • Ill Girl:
    • Sayuri suffers from aplastic anemia, leading her to be hospitalized at Yurigahama Hospital and becoming Kaori's first assigned patient.
    • Mayuki suffers from a strange disease that causes her to age backwards. She only has three years left to live when Kaori first meets her.
  • The Jail Bait Wait: In Ami's good ending, Kaori insists they have to wait for her to graduate high school before they can kiss or be openly romantic. Not the case in Mayuki's romance ending, even though Mayuki is physically younger (but mentally older).
  • Jerkass Has a Point: While she's taking it out on the wrong person, Sayuri is right that assigning Kaori to her wasn't the best idea. Their personalities clash way too hard and both cause Kaori plenty of stress when she's not used to the job enough to handle it, which places Sayuri at risk by association.
  • Kansai Regional Accent: Yamanouchi has a strong Kansai dialect. She tried to subdue it when she became a nurse but dropped the act after a while. The English text of the game writes it out to give her a Southern drawl.
  • Meganekko: Hatsumi all the time and Yamanouchi during the evenings.
  • Merlin Sickness: Mayuki is aging backwards and becomes a baby in her bad end.
  • Multiple Endings: There are thirteen main endings: a good ending and bad ending for each of the six love interests, and a "common ending" where Kaori doesn't really hook up with anyone. There are also several other bad endings that don't roll the credits or earn achievements, such as not preventing Nagisa from jumping off the roof.
  • Mystical White Hair: Mayuki's hair is a sort of blue-silver, contrasting with her apparent youth, and is the character most directly tied to mystical phenomena.
  • Ocean Awe: Sayuri hasn't visited the ocean before because of her health. She finally gets the chance in her story route, in both her good and bad endings.
  • The One That Got Away: Sayuri's Common Route ending. Sayuri feels she just can't open herself to Kaori and leaves.
  • Older Than They Look: Mayuki looks like she's under twelve, but is actually forty-five.
  • Otaku Surrogate: Yamanouchi draws manga in her spare time. In her story route she's considering going at it full time.
  • Please Don't Leave Me: Some of Kaori's relationships go this way, depending on the route.
    • During her Good End pursuit of Hatsumi, Kaori suspects Hatsumi is cheating on her. She's not, she's just giving instruction to Sayuri.
    • A darker version during Yamanouchi's bad end. Kaori would rather be in an unhealthy relationship.
  • Rooftop Concert: During Ami's story route she will play her instrument on the rooftop for some of the staff and patients.
  • Sempai/Kohai:
    • Nagisa and Kaori. Both went to high school together and both work at the hospital together. Nagisa also becomes Kaori's preceptor to help her train on the job. Their positions later flip in Nagisa's route when Nagisa returns from surgery and is the charge for Kaori to help her become reacquainted with the ward and improve as a nurse.
    • Like with Nagisa, Kaori will become a Preceptor to Sayuri during Sayuri's Good Ending route as well as Hatsumi's Good Ending route.
  • Sitting on the Roof: Ami and Sayuri are fond of going to the roof in their story routes. For Ami she can practice her instrument up there without disturbing the others and Sayuri will go there alone to think or play with a little girl in the ward.
  • Sugar-and-Ice Personality: Sayuri. She's very, very spiteful and venomous to both Kaori and Nagisa, but she's very sweet to Hatsumi. She also ends up making friends with Yamanouchi, Ami, and the entire childrens' room pretty easily. What prevents her from being a tsundere is that despite her 180 in her own route, she legitimately hates Kaori, and hates Nagisa by association.
  • Trash of the Titans: Hatsumi keeps a very messy apartment and seldom throws anything out.
  • I Want My Beloved to Be Happy: Nagisa feels this way about Kaori in most routes you'll follow.
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