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Useful Notes / The Simpsons Voice Actors

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The main cast. Not pictured: one of the most epic lists of guest stars in the history of television.
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An index for the voice actors and voice actresses of The Simpsons who have a page on TV Tropes.


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    Regular cast 

Main cast

  • Dan Castellaneta: Homer Jay Simpson, Abraham "Abe" Jedediah Simpson II, Herschel "Krusty the Clown" Krustofski, Barney Gumble, Groundskeeper Willie, Mayor Joseph Quimby, Hans Moleman, Sideshow Mel, Gil Gunderson, Squeaky Voiced Teen, Kodos, Itchy.
  • Julie Kavner: Marjorie "Marge" Jacqueline Simpson (née Bouvier), Jacqueline Ingrid Bouvier (née Gurney), Patricia "Patty" Bouvier, Selma Bouvier.
  • Nancy Cartwright: Bartholomew "Bart" Jo-Jo Simpson, Margaret "Maggie" Evelyn Simpson, Ralph Wiggum, Nelson Muntz, Kearney, Todd Flanders, Ling Bouvier.
  • Yeardley Smith: Lisa Marie Simpson, Margaret "Maggie" Evelyn Simpson.
  • Hank Azaria: Apu Nahasapeemapetilon, Morris "Moe" Szyslak, Carl Carlson, Chief Clarence "Clancy" Wiggum, Officer Lou, Jeffrey "Comic Book Guy" Albertson, Kirk Van Houten, Professor John Frink Jr., Superintendent Gary Chalmers, Cletus Spuckler, Snake Jailbird, Captain Horatio McCallister, Bumblebee Man, Disco Stu, Dr. Nick Riviera, Duffman.
  • Harry Shearer: Nedward "Ned" Flanders, Charles "Monty" Montgomery Burns, Waylon J. Smithers Jr., Principal W. Seymour Skinner, Lenny Leonard, Kent Brockman, Reverend Timothy Lovejoy, Dr. Julius Hibbert, Otto Man, Jasper Beardley, Rainier Wolfcastle, Kang, Scratchy.

Recurring cast

  • Albert Brooks: Cowboy Bob, Jacques, Brad Goodman, Hank Scorpio, Tab Spangler, Russ Cargill, French Guy, Dr. Raufbold.
  • Glenn Close: Mona Simpson.
  • Christopher Collins: Mr. Burns (Season 1 only, replaced by Harry Shearer).
  • Marcia Mitzman Gaven: Replaced Maggie Roswell (seen below) for seasons 11-14.
  • Kelsey Grammer: Robert "Sideshow Bob" Terwilliger.
  • Doris Grau: Lunchlady Doris (eventually replaced by Tress MacNeille after her death)
  • Pamela Hayden: Milhouse van Houten, Jimbo Jones, Rod Flanders, Janey Powell, Sarah Wiggum.
  • Phil Hartman: Lionel Hutz, Troy McClure.
  • Jan Hooks: Manjula Nahasapeemapetilon (replaced by Tress MacNeille after her death)
  • Jane Kaczmarek: Judge Constance Harm.
  • Tress MacNeille: Agnes Skinner, Lindsey Naegle, Brandine Spuckler, Crazy Cat Lady, Cookie Kwan, Bernice Hibbert, Manjula Nahasapeemapetilon, Lunchlady Doris, Dolph Starbeam.
  • Joe Mantegna: Fat Tony.
  • Jackie Mason: Hyman Krustofsky.
  • Kevin Michael Richardson: Anger Watkins.
  • Maggie Roswell: Elizabeth Hoover, Maude Flanders, Helen Lovejoy, Luann van Houten, Mary Bailey, Princess Kashmir, Martha Quimby.
  • Russi Taylor: Sherri, Terri, Martin Prince, Wendell Borton, Üter Zörker.
  • Marcia Wallace: Edna Krabappel.
  • Frank Welker: Santa's Little Helper, Snowball II, various animals.

    Guest stars 

A-F

  • 50 Cent: Himself in Episode #344 "Pranksta Rap".
  • Aerosmith: Themselves in Episode #45 "Flaming Moe's".
  • Shohreh Aghdashloo: Mina bin Laden in Episode #427 "Mypods and Broomsticks".
  • Jason Alexander: Bourbon Verlander in Episode #615 "Caper Chase".
  • Alison Krauss & Union Station: They perform the theme song in Episode #500 "At Long Last Leave".
  • Steve Allen: Electronically altered voice of Bart in Episode #53 "Separate Vocations".
    • Himself in Episode #125 "'Round Springfield".
  • Gillian Anderson: Dana Scully in Episode #163 "The Springfield Files".
  • Andre Agassi: Himself in Episode #260 "Tennis the Menace".
  • Judd Apatow: Himself in Episode #539 "Steal This Episode".
  • Will Arnett: Deputy Director Gratman in Episode #539 "Steal This Episode".
  • Tom Arnold: Himself in Episode #230 "Treehouse of Horror X".
  • Edward Asner: Newspaper editor in Episode #229 "Guess Who's Coming to Criticize Dinner?".
  • Diedrich Bader: Sheriff in Episode #245 "Kill the Alligator and Run".
  • Alec Baldwin: Himself in Episode #208 "When You Dish Upon a Star".
    • Caleb Thorn in Episode #357 "Bonfire of the Manatees".
  • Anne Bancroft: Dr. Zweig in Episode #114 "Fear of Flying".
  • Sacha Baron Cohen: Jakob in Episode #457 "The Greatest Story Ever D'ohed".
  • Drew Barrymore: Sophie in Episode #251 "Insane Clown Poppy".
  • Angela Bassett: Michelle Obama in Episode #456 "Stealing First Base".
  • Mario Batali: Himself in #491 "The Food Wife" and #622 "Treehouse of Horror XXVIII".
  • Jason Bateman: Himself in Episode #355 "Home Away from Homer".
  • Ed Begley Jr.: Himself in Episode #216 "Homer to the Max" and #433 "Gone Maggie Gone".
  • Kristen Bell: Harper Jambowski in Episode #580 "Friend with Benefit".
  • H. Jon Benjamin: Bob Belcher in Episode #642 "My Way or the Highway to Heaven".
  • Gregg Berger: Various animals in Episode #471 "How Munched Is That Birdie in the Window?".
  • Halle Berry: Herself in Episode #478 "Angry Dad: The Movie".
  • Justin Bieber: Himself in Episode #528 "The Fabulous Faker Boy".
  • Jack Black: Milo in Episode #407 "Husbands and Knives".
  • Tony Blair: Himself in Episode #317 "The Regina Monologues".
  • blink-182: Themselves in Episode #302 "Barting Over".
  • Rachel Bloom: Annette in Episode #620 "Springfield Splendor".
  • Emily Blunt: Juliet Hobbes in Episode #429 "Lisa the Drama Queen".
  • Peter Bogdanovich: Psychologist in Episode #392 "Yokel Chords".
  • Ernest Borgnine: Himself in Episode #89 "Boy-Scoutz 'n the Hood".
  • Anthony Bourdain: Himself in Episode #491 "The Food Wife".
  • Billy Boyd: Himself in Episode #619 "The Serfsons".
  • Russell Brand: Himself in Episode #478 "Angry Dad: The Movie".
  • James L. Brooks: Himself in Episode #304 "A Star Is Born Again".
  • Mel Brooks: Himself in Episode #120 "Homer vs. Patty and Selma".
  • Pierce Brosnan: Ultrahouse's Pierce Brosnan voice and Himself in Episode #270 "Treehouse of Horror XII".
  • James Brown: Himself in Episode #88 "Bart's Inner Child".
  • Carrie Brownstein: Emily in Episode #515 "The Day the Earth Stood Cool".
  • Bill Burr: Townie, Man in Tunnel, Cart-Warning Man in Episode #599 "The Town".
  • Steve Buscemi: Himself in Episode #311 "Brake My Wife, Please".
    • Dwight David Diddlehoffer in Episode #404 "I Don't Wanna Know Why the Caged Bird Sings".
  • Neve Campbell: Cassandra in Episode #448 "Rednecks and Broomsticks".
  • Lizzy Caplan: Virginia Johnson in Episode #612 "Kamp Krustier".
  • Steve Carell: Dan Gillick in Episode #513 "Penny Wiseguys".
  • Drew Carey: Himself in Episode #420 "All About Lisa".
  • George Carlin: Munchie in Episode #209 "D'oh-in in the Wind".
  • Johnny Cash: Coyote in Episode #162 "The Mysterious Voyage of Homer".
  • Kim Cattrall: Chloe Talbot in Episode #339 "She Used to Be My Girl".
  • Michael Cera: Nick in Episode #499 "The Daughter Also Rises".
  • Don Cheadle: Brother Faith in Episode #237 "Faith Off".
  • Cheech & Chong: Themselves in Episode #480 "A Midsummer's Nice Dream".
  • Michael Chiklis: Handsome Boston quarterback in Episode #599 "The Town".
  • Tom Clancy: Himself in Episode #323 "Diatribe of a Mad Housewife".
  • Dick Clark: Himself in Episode #230 "Treehouse of Horror X".
  • Jermaine Clement: Ethan Ballantyne in Episode #465 "Elementary School Musical".
  • Stephen Colbert: Colby Kraus in Episode #401 "He Loves to Fly and He D'ohs".
  • Gary Coleman: Himself in Episode #235 "Grift of the Magi", #250 "A Tale of Two Springfields", and #261 "Day of the Jackanapes".
  • Shawn Colvin: Rachel Jordan in Episode #240 "Alone Again, Natura-Diddily".
  • Tim Conway: Himself in "The Simpsons Spin-off Showcase".
  • Steve Coogan: Rowan Priddis in Episode #505 "A Totally Fun Thing That Bart Will Never Do Again".
  • Anderson Cooper: Himself in Episode #536 "The Kid Is All Right".
  • Bryan Cranston: Stradivarius Cain in Episode #506 "The Spy Who Learned Me".
  • David Crosby: Himself in Episode #80 "Marge in Chains" and Episode #82 "Homer's Barbershop Quartet".
  • Benedict Cumberbatch: British Prime Minister in Episode #520 "Love Is a Many-Splintered Thing".
  • Willem Dafoe: Commandent in Episode #178 "The Secret War of Lisa Simpson".
    • Jack Lassen in Episode #559 "Blazed and Confused".
  • Andy Daly: Judge Dowd in #632 "Fears of a Clown".
  • Rodney Dangerfield: Larry Burns in Episode #157 "Burns, Baby Burns".
  • William Daniels: KITT in Episode #205 "The Wizard of Evergreen Terrace".
  • Ted Danson: Sam Malone in Episode #114 "Fear of Flying".
  • Richard Dawkins: Himself in Episode #523 "Black Eyed, Please".
  • Ellen DeGeneres: Herself in Episode #464 "Judge Me Tender".
  • Guillermo del Toro: Himself in "101 Mitigations".
  • Kat Dennings: Valerie in Episode #626 "Mr. Lisa's Opus".
  • Emily Deschanel: Herself in Episode #640 "Bart's Not Dead".
  • Zooey Deschanel: Mary Spuckler in Episode #417 "Apocalypse Cow", Episode #509 "Moonshine River" and Episode #520 "Love is a Many-Splintered Thing".
  • Danny DeVito: Herb Powell in Episode #28 "Oh Brother, Where Art Thou?", Episode #59 "Brother, Can You Spare Two Dimes?" and Episode #519 "The Changing of the Guardian".
  • John DiMaggio: Bender in Episode #350 "Future-Drama", Episode #558 "Simpsorama", and The Simpsons Game.
  • Dixie Chicks: Themselves in Episode #416 "Papa Don't Leech".
  • Kirk Douglas: Chester J. Lampwick in Episode #146 "The Day the Violence Died".
  • Fran Drescher: Female Golem in Episode #382 "Treehouse of Horror XVII".
  • Adam Driver: Adam Sackler in Episode #575 "Every Man's Dream".
  • David Duchovny: Fox Mulder in Episode #163 "The Springfield Files".
  • Lena Dunham: Candace, Hannah Helene Horvath in Episode #575 "Every Man's Dream".
  • Harlan Ellison: Himself in Episode #540 "Married to the Blob".
  • Robert Englund: Freddy Krueger in Episode #207 "Treehouse of Horror IX".
  • R. Lee Ermey: Colonel Leslie Hapablap in Episode #137 "Sideshow Bob's Last Gleaming" and Episode #569 "Waiting for Duffman".
  • Fall Out Boy: They perform the ending theme song in Episode #429 "Lisa the Drama Queen".
  • Tina Fey: Ms. Cantwell in Episode #523 "Black-Eyed, Please".
  • Fyvush Finkel: As Himself playing Krusty in Episode #181 "Lisa's Sax".
  • Miriam Flynn: Miss Barr in Episode #6 "Moaning Lisa".
  • Jane Fonda: Maxine Lombard in Episode #557 "Opposites A-Frack".
  • June Foray: Babysitting Lady in Episode #13 "Some Enchanted Evening".
  • Will Forte: King Toot in Episode #560 "Covercraft".
  • Jodie Foster: Maggie Simpson in Episode #440 "Four Great Women and a Manicure".
  • Brendan Fraser: Brad in Episode #201 "King of the Hill".

G-L

  • Gal Gadot: Herself in Episode #640 "Bart's Not Dead".
  • Janeane Garofalo: Herself in Episode #193 "The Last Temptation of Krust" and Episode #494 "The Ten-Per-Cent Solution".
  • Doris Kearns Goodwin: Herself in #599 "The Town".
  • Green Day: Themselves in The Simpsons Movie.
  • Neil Gaiman: Himself in Episode #492 "The Book Job".
    • Snowball II in Episode #622 "Treehouse of Horror XXVIII".
  • Andy García: Slick Publisher in Episode #492 "The Book Job".
  • Sarah Michelle Gellar: Gina Vendetti in Episode #329 "The Wandering Juvie" and Episode #509 "Moonshine River".
  • Ricky Gervais: Charles Heathbar in Episode #371 "Homer Simpson, This is Your Wife".
  • Mel Gibson: Himself in Episode #227 "Beyond Blunderdome".
  • Jeff Goldblum: MacArthur Parker in Episode #147 "A Fish Called Selma".
  • John Goodman: Meathook in Episode #234 "Take My Wife, Sleaze".
  • Elliott Gould: Elliott Gould in Episode #299 "The Dad Who Knew Too Little".
  • Topher Grace: Donny in Episode #413 "The Debarted".
  • Kathy Griffin: Francine in Episode #264 "Bye Bye Nerdie".
  • Matt Groening: Himself in multiple episodes of the show, along with The Simpsons Game.
  • Christopher Guest: Nigel Tufnel in Episode #57 "The Otto Show".
  • Bill Hader: Slava in Episode #528 "The Fabulous Baker Boy".
    • Manacek in Episode #630 "Homer is Where the Art Isn't."
  • Larry Hagman: Wallace Brady in Episode #377 "The Monkey Suit".
  • Mark Hamill: Himself, Leavelle, Theater Owner in Episode #212 "Mayored to the Mob".
  • Jon Hamm: FBI Agent in Episode #473 "Donnie Fatso".
  • Armie Hammer: Cameron Winklevoss, Tyler Winklevoss in Episode #497 "The D'oh-cial Network".
  • Tom Hanks: Himself in The Simpsons Movie.
  • Alyson Hannigan: Melody Juniper in Episode #475 "Flaming Moe".
  • Dan Harmon: Himself in Episode #620 "Springfield Splendor".
  • Jess Harnell: Various animals in Episode #271 "The Parent Rap".
  • Woody Harrelson: Woody Boyd in Episode #114 "Fear of Flying".
  • Neil Patrick Harris: Himself in Episode #39 "Bart the Murderer".
  • George Harrison: Himself in Episode #82 "Homer's Barbershop Quartet".
  • Anne Hathaway: Jenny in Episode #437 "The Good, the Sad and the Ugly" and Episode #509 "Moonshine River".
    • Princess Penelope in Episode #451 "Once Upon a Time in Springfield".
  • Tony Hawk: Himself in Episode #302 "Barting Over".
  • Stephen Hawking: Himself in Episode #225 "They Saved Lisa's Brain" and Episode #351 "Don't Fear The Roofer".
  • Taraji P. Henson: Praline in Episode #608-609 "The Great Phatsby".
  • David Herman: Scruffy in Episode #558 "Simpsorama".
  • Don Hertzfeldt: "The Sampsans" in Episode #553 "Clown in the Dumps" (Couch Gag).
  • Werner Herzog: Walter Hotenhoffer in Episode #479 "The Scorpion's Tale".
  • Jonah Hill: Andy Hamilton in Episode #447 "Pranks and Greens".
  • Dustin Hoffman: Mr. Bergstrom in Episode #32 "Lisa's Substitute".
  • Bob Hope: Himself in Episode #63 "Lisa the Beauty Queen".
  • Ron Howard: Himself in Episode #208 "When You Dish Upon a Star" and Episode #232 "Hello Gutter, Hello Fadder".
  • Helen Hunt: Renee in Episode #194 "Dumbell Indemnity".
  • Eric Idle: Declan Desmond in Episode #307 "Scuse Me While I Miss the Sky", Episode #340 "Fat Man and Little Boy", Episode #391 "Springfield Up" and Episode #506 "The Spy Who Learned Me".
  • Jeremy Irons: Bar Rag in Episode #498 "Moe Goes from Rags to Riches".
  • Eddie Izzard: Nigel Bakerbutcher in Episode #461 "To Surveil With Love".
  • Michael Jackson: Leon Kompowsky in Episode #36 "Stark Raving Dad".
  • Mick Jagger: Himself in Episode #293 "How I Spent My Strummer Vacation".
  • LeBron James: Himself in Episode #343 ""Homer and Ned's Hail Mary Pass".
  • Allison Janney: Julia in Episode #598 "Friends and Family".
  • Elton John: Himself in Episode #217 "I'm with Cupid".
  • James Earl Jones: Moving Man, Serak the Preparer, The Raven Narrator in Episode #16 "Treehouse of Horror".
    • Alternate universe Maggie Simpson in Episode #109 "Treehouse of Horror V".
  • Rashida Jones: Portia in Episode #519 "The Changing of the Guardian".
  • Tom Jones: Himself in Episode #66 "Marge Gets a Job".
  • Mike Judge: Hank Hill in Episode #184 "Bart Star".
  • Michael Keaton: Jack Crowley in Episode #258 "Pokey Mom".
  • Keegan-Michael Key: Jazzy James in Episode #608-609 "The Great Phatsby".
  • Stephen King: Himself in Episode #251 "Insane Clown Poppy".
  • Jane Krakowski: Zhenya in Episode #528 "The Fabulous Baker Boy".
  • Nick Kroll: Lem in Episode #578 "Halloween of Horror".
  • Lisa Kudrow: Alex Whitney in Episode #204 "Lard of the Dance".
  • Lady Gaga: Herself in Episode #508 "Lisa Goes Gaga".
  • Phil LaMarr: Hermes Conrad in Episode #558 "Simpsorama".
    • Auctioneer, Informed Party Guest in Episode #608-609 "The Great Phatsby".
  • Lisa Lampanelli: Ramona in Episode #530 "Dangers on a Train".
  • Martin Landau: The Great Raymondo in Episode #482 "The Great Simpsina".
  • Hugh Laurie: Roger in Episode #468 "Treehouse of Horror XXI".
  • Lucy Lawless: Herself in Episode #230 "Treehouse of Horror X".
  • Cloris Leachman: Mrs. Glick in Episode #34 "Three Men and a Comic Book".
  • Stan Lee: Himself in Episode #287 "I Am Furious (Yellow)", Episode #540 "Married to the Blob", and Episode #615 "Caper Chase".
  • Jack Lemmon: Frank Ormand in Episode #164 "The Twisted World of Marge Simpson".
  • Jay Leno: Himself in Episode #193 "The Last Temptation of Krust" and Episode #594 "To Courier with Love".
  • David Letterman: Himself in Episode #497 "The D'oh-cial Network".
  • Jerry Lewis: Professor John Frink Sr. in Episode #314 "Treehouse of Horror XIV".
  • Ray Liotta: Morty Szyslak in Episode #634 "King Leer".
  • Lucy Liu: Madam Wu in Episode #347 "Goo Goo Gai Pan".
  • Christopher Lloyd: Jim Ignatowski in Episode #566 "My Fare Lady".
  • Eva Longoria: Isabel Gutierrez in Episode #536 "The Kid is All Right".
  • Julia Louis-Dreyfus: Gloria in Episode #273 "A Hunka Hunka Burns in Love", Episode #404 "I Don't Wanna Know Why the Caged Bird Sings" and Episode #421 "Sex, Pies and Idiot Scrapes".
  • Patti LuPone: Cheryl Monroe in Episode #651 "The Girl on the Bus".
  • Jane Lynch: Roz Davis in Episode #490 "Replaceable You".
    • Jeanie in Episode #649 "Tis the 30th Season".
  • Natasha Lyonne: Sophie in Episode #606 "The Nightmare After Krustmas".

M-S

  • Seth MacFarlane: Ben in Episode #530 "Dangers on a Train".
  • John Mahoney: Dr. Robert Terwilliger, Sr. in Episode #408 "Funeral for a Fiend".
  • Mako: Battling Seizure Robot in Episode #226 "Thirty Minutes Over Tokyo".
  • Garry Marshall: Larry Kidkill in Episode #233 "Eight Misbehavin'".
    • Sheldon Leavitt in Episode #476 "Homer the Father".
  • Penny Marshall: Ms. Botz in Episode #13 "Some Enchanted Evening".
  • Andrea Martin: Apu's Mother in Episode "The Two Mrs. Nahasapeemapetilons".
  • Steve Martin: Ray Patterson in Episode #200 "Trash of the Titans".
  • Karen Maruyama: Dancing Woman in "Marge We Trust" and Japanese Stewardess in "Thirty Minutes Over Tokyo".
  • Jack McBrayer: Ewell Freestone in Episode #482 "The Great Simpsina".
  • Paul McCartney: Himself in Episode #133 "Lisa The Vegetarian".
  • Frances McDormand: Melanie Upfoot in Episode #375 "Girls Just Want to Have Sums".
  • Michael McKean: David St. Hubbins in Episode #57 "The Otto Show".
    • Jerry Rude in Episode #224 "Monty Can't Buy Me Love".
  • Ian McKellen: Himself in Episode #317 "The Regina Monologues".
  • Kate McKinnon: Hettie Mae Boggs in Episode #588 "Gal of Constant Sorrow".
  • Ed McMahon: Himself in Episode #207 "Treehouse of Horror IX".
  • Sam McMurray: SNPP Employee/Duff Commercial VO in Episode #3 "Homer's Odyssey".
    • Gulliver Dark in Episode #10 "Homer's Night Out".
  • Audrey Meadows: Bea Simmons in Episode #30 "Old Money".
  • Colm Meaney: Tom O'Flanagan in Episode #434 "In the Name of the Grandfather".
  • Stephen Merchant: CONRAD in Episode #584 "The Girl Code".
  • Metallica: Themselves in Episode #379 "The Mook, the Chef, the Wife and Her Homer".
  • Lea Michele: Sarah in Episode #465 "Elementary School Musical".
  • Cory Monteith: Flynn in Episode #465 "Elementary School Musical".
  • Alan Moore: Himself in Episode #407 "Husbands and Knives".
  • Mandy Moore: Tabitha Vixx in Episode #378 "Marge and Homer Turn a Couple Play".
  • Michael Moore: Himself in Episode #316 "The President Wore Pearls".
  • Elisabeth Moss: Gretchen in Episode #534 "Labor Pains".
  • Martin Mull: Seth in Episode #209 "D'oh-in in the Wind".
  • Frankie Muniz: Thelonius in Episode #266 "Trilogy of Error".
  • Rupert Murdoch: Himself in Episode #215 "Sunday, Cruddy Sunday".
  • Charles Napier: Warden in Episode #258 "Pokey Mom" and Episode #329 "The Wandering Juvie".
    • Grant Conner in Episode #318 "The Fat and the Furriest".
    • Officer Krackney in Episode #349 "The Seven-Beer Snitch".
  • Liam Neeson: Father Sean in Episode #356 "The Father, the Son and the Holy Guest Star".
  • Sam Neill: Molloy in Episode #92 "Homer the Vigilante".
  • Nichelle Nichols: Herself in Episode #332 "Simple Simpson".
  • Leonard Nimoy: Himself in Episode #71 "Marge vs. the Monorail" and Episode #163 "The Springfield Files".
  • Edward Norton: Devon Bradley in Episode #255 "The Great Money Caper".
    • Reverend Elijah Hooper in Episode #526 "Pulpit Friction".
  • *NSYNC: Themselves in Episode #262 "New Kids on the Blecch".
  • Ted Nugent: Himself in Episode #404 "I Don't Wanna Know Why the Caged Bird Sings".
  • Conan O'Brien: Himself in Episode #93 "Bart Gets Famous".
  • Nick Offerman: Captain Bowditch in Episode #554 "The Wreck of the Relationship".
  • Keith Olbermann: Himself in Episode #408 "Funeral for a Fiend".
  • John Oliver: Booth Wilkes-John in Episode #551 "Pay Pal".
  • Edward James Olmos: Pit Master in Episode #576 "Cue Detective".
  • Kaitlin Olson: Quinn Hopper in Episode #584 "The Girl Code".
  • Mary-Kate and Ashley Olsen: Themselves in Episode #323 "Diatribe of a Mad Housewife".
  • Patton Oswalt: T-Rex in Episode #515 "The Day the Earth Stood Cool".
  • Elliot Page: Alaska Nebraska in Episode #439 "Waverly Hills 9-0-2-1-D'oh".
  • Joe Pantoliano: Dante Calabresis in Episode #379 "The Mook, the Chef, the Wife and Her Homer".
  • Mandy Patinkin: Hugh Parkfield in Episode #122 "Lisa's Wedding".
  • Aaron Paul: Jesse Pinkman (live action) in Episode #525 "What Animated Women Want" (Couch Gag).
  • Penn & Teller: Themselves in Episode #232 "Hello Gutter, Hello Fadder" and Episode #482 "The Great Simpsina".
  • Rhea Perlman: Carla Tortelli in episode #114 "Fear of Flying".
  • Luke Perry: Himself in Episode #81 "Krusty Gets Kancelled".
  • Katy Perry: Herself (live action) in Episode #472 "The Fight Before Christmas".
  • Matthew Perry: Ultrahouse's Matthew Perry voice in Episode #270 "Treehouse of Horror XII".
  • Michelle Pfeiffer: Mindy Simmons in Episode #90 "The Last Temptation of Homer".
  • David Hyde Pierce: Cecil Terwilliger in Episode #169 "Brother from Another Series" and Episode #408 "Funeral for a Fiend".
  • George Plimpton: Himself in Episode #303 "I'm Spelling as Fast as I Can".
  • Amy Poehler: Jenda in Episode #350 "Future-Drama" and Episode #548 "Days of Future Future".
  • Natalie Portman: Darcy in Episode #390 "Little Big Girl" and Episode #509 "Moonshine River".
  • Brian Posehn: Dumlee in Episode #614 "A Father's Watch".
  • Parker Posey: Becky in Episode #247 "It's a Mad, Mad, Mad, Mad Marge".
  • Tom Poston: Capital City Goofball in Episode #18 "Dancin' Homer".
  • Daniel Radcliffe: Edmund in Episode #468 "Treehouse of Horror XXI".
    • Diggs in Episode #542 "Diggs".
    • Himself in Episode #633 "No Good Read Goes Unpunished".
  • Mary Lynn Rajskub: Chloe O'Brien in Episode #399 "24 Minutes".
  • Red Hot Chili Peppers: Themselves in Episode #81 "Krusty Gets Kancelled".
  • Christina Ricci: Erin in Episode #153 "Summer of 4 ft. 2".
  • Lionel Richie: Himself in Episode #401 "He Loves to Fly and He D'ohs".
  • Amber Riley: Herself in Episode $465 "Elementary School Musical".
  • Joan Rivers: Annie Dubinsky in Episode #494 "The Ten-Per-Cent Solution".
  • Tim Robbins: Jim Hope in Episode #235 "Grift of the Magi".
  • Seth Rogen: Lyle McCarthy in Episode #442 "Homer the Whopper".
    • Himself in Episode #539 "Steal This Episode".
  • Justin Roiland: Rick Sanchez and Morty Smith in Episode #574 "Mathlete's Feat" (Couch Gag).
  • Ray Romano: Ray Magini in Episode #351 "Don't Fear the Roofer".
  • Mickey Rooney: Himself in Episode #130 "Radioactive Man".
  • Anika Noni Rose: Rita La Fleur in Episode #512 "Gone Abie Gone".
  • Isabella Rossellini: Astrid Weller in Episode #222 "Mom and Pop Art".
  • J. K. Rowling: Herself in Episode #317 "The Regina Monologues".
  • Paul Rudd: Dr. Zander in Episode #481 "Love is a Many Strangled Thing".
  • Maya Rudolph: Julia in Episode #402 "Homer of Seville".
  • RuPaul: Queen Chantein in Episode #??? "Werking Mom".
  • Meg Ryan: Dr. Stacy Swanson in Episode #392 "Yokel Chords".
  • Winona Ryder: Allison Taylor in Episode #105 "Lisa's Rival".
  • Katey Sagal: Leela in Episode #558 "Simpsorama".
  • Jennifer Saunders: Phoebe Pratt in Episode #616 "Looking for Mr. Goodbart".
  • Kristen Schaal: Taffy in Episode #484 "Homer Scissorhands".
  • Amy Schumer: Daphne Burns in Episode #597 "Monty Burns' Fleeing Circus".
  • Ryan Seacrest: Himself in Episode #464 "Judge Me Tender".
  • George Segal: Nick in Episode #641 "Heartbreak Hotel".
  • Andy Serkis: Cleanie in Episode #309 "Dude, Where's My Ranch?".
  • Wallace Shawn: Wallace in Episode #655 "I Want You (She's So Heavy)".
  • Martin Sheen: Real Seymour Skinner in Episode #180 "The Principal and the Pauper".
  • Michael Sheen: William Masters in Episode #612 "Kamp Krustier".
  • Ed Sheeran: Brendan Beiderbecke in Episode #628 "Haw-Haw Land".
  • Brooke Shields: Herself in Episode #78 "The Front".
  • Martin Short: Guthrie Frenel in Episode #620 "Springfield Splendor".
  • Sarah Silverman: Nikki McKenna in Episode #456 "Stealing First Base" and Episode #509 "Moonshine River".
    • Herself in Episode #553 "Clown in the Dumps".
    • Rachel Cohen in Episode #600 "Treehouse of Horror XXVII".
  • Sir Mix-A-Lot: "Baby Likes Fat" singer in Episode #382 "Treehouse of Horror XVII".
  • J. K. Simmons: J. Jonah Jameson in Episode #384 "Moe'N'a Lisa".
    • Tabloid Editor in Episode #394 "Homerazzi".
    • J.J. Gruff in Episode #631 "3 Scenes Plus a Tag From a Marriage".
  • John Slattery: Robert Marlowe in Episode #493 "The Man in the Blue Flannel Pants".
  • Snoop Dogg: Himself in Episode #608-609 "The Great Phatsby".
  • Rich Sommer: Young Man in Episode #566 "My Fare Lady".
  • Britney Spears: Herself in Episode #238 "The Mansion Family".
  • Art Spiegelman: Himself in Episode #407 "Husbands and Knives".
  • Brent Spiner: Robots in Episode #503 "Them, Robot".
  • Jerry Springer: Himself in Episode #207 "Treehouse of Horror IX".
  • Ringo Starr: Himself in Episode #31 "Brush with Greatness".
  • Daniel Stern: Narrator in Episode #24 "Three Men and a Comic Book".
  • Frances Sternhagen: Mrs. Bellamy in #290 "The Frying Game".
  • Jon Stewart: Himself in Episode #410 "E Pluribus Wiggum".
  • Patrick Stewart: Number One in Episode #115 "Homer the Great".
    • Vigorous Older Man in Episode #528 "The Fabulous Baker Boy".
  • Ben Stiller: Garth Motherloving in Episode #277 "Sweets and Sour Marge".
  • Sting: Himself in Episode #48 "Radio Bart".
  • Meryl Streep: Jessica Lovejoy in Episode #110 "Bart's Girlfriend".
  • Cecily Strong: Megan Matheson in Episode #630 "Homer is Where the Art Isn't."
  • Donald Sutherland: Hollis Hurlbut in Episode #144 "List the Iconoclast".
  • Kiefer Sutherland: Jack Bauer in Episode #399 "24 Minutes".
    • Wayne Slater in Episode #487 "The Falcon and the D'ohman".

T-Z

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