- Acting for Two: In the stage version, Kelekian and Vivian's dad are played by the same actor, possibly as a comment on the inherently paternalistic relationship between doctors and patients.
- Science Marches On: The play was originally performed in 1999 and as a result, Vivian's fate is completely inexorable. Had it been set in the present day, Vivian probably would have been able to get tested for the faulty breast cancer gene, which has also been linked to ovarian cancer. Her mum's death would have been a red flag. It still might not have been enough to save her life or stop her from becoming ill, but she would have at least had a warning and would have been able to take some preventative steps.
Trivia / Wit