I Knew It!: Fanwork depicted Dr. Flug as a Fatherly Scientist to 5.0.5, before the show made it clear that they indeed have this kind of relationship.
Keep Circulating the Tapes: Alan Ituriel's original 2012 shorts prior to the series getting picked up by Cartoon Network are no longer available on his website, "That Place To Hang Out". They can still be found on YouTube, however.
Short Run in Peru: Episodes are usually first released in Spanish for CN's Latin American feed (and YouTube channel), but Word of God says it was animated to the English dialogue. Unusually, The Lost Cases Of Elmore was first uploaded by CN Brazil, several minutes before the Latin America upload.
Word of God: The show creator, Alan Ituriel, has answered many questions about the show and characters on Twitter. Some of them include Black Hat filming his commercials with a robotic camera, Dr. Flug being a Cowardly Lion, and the device on Demencia's leg being a tracking device.
Write Who You Know: According to Alan Ituriel, Black Hat is based on his father and 5.0.5 is based on himself as a child (which has invited some Wild Mass Guessing). On a happier note, Dr. Flug is explicitly based on Alan's best friend, to the extent of calling him to ask for his opinion when a fan asked Alan whether Flug likes pancakes. Meanwhile, Demencia, though based off villain-worshiping fangirls in general, was also inspired by the girl who introduced him to anime.