- Channel Hop: Before the series aired, the original press release stated that it would air in the US on The Hub. In the fall of 2014, however, Discovery Communications bought out 10% of Hasbro's holdings in the channel, renaming it Discovery Family, and limiting Hasbro-scheduled programming to daytime. Hasbro then decided to move the program to Cartoon Network, believing that Discovery Family's apparent girl-leaning demographics were not appropriate for the show. (Transformers: Rescue Bots and reruns of the G1 cartoon carried over to Discovery Family.)
- Completely Different Title: In Japan is called Transformers Adventure.
- I Knew It!: Many viewers have called it when in the final episode Freedom Fighters, The High Council are revealed to be Cyclonus and four other Decepticons posing as Autobots.
- Name's the Same:
- The title Transformers: Robots in Disguise can refer to this show, the comic beginning in 2012 that is a continuation of the IDW G1 universe and had it's name changed as above, the second phase of the Transformers: Prime toyline, or the 2001 American localization of the 2000 anime Car Robots.
- With an example set in the same universe, Transformers: War for Cybertron featured a character named "Slipstream" based on the female Starscream clone from Transformers Animated, but this one has a male Minicon. Likewise,Transformers: Rise of the Dark Spark featured an Autobot deployer called Steeljaw based on the Cassette Autobot from G1, but here there's a full sized Decepticon, who is also the Big Bad, called Steeljaw. As noted below, Word of God pulled a Decomposite Character and said this Grimlock isn't the same one as in the G1-esque Grimlock in Transformers: Fall of Cybertron, hence another case of this in the same universe as well. TFWiki.net's stance on Sideswipe and Kickback is they're likewise not the same characters as in the Cybertron game.
- The Other Darrin:
- Darren Criss replaces Travis Willingham as Sideswipe. As noted above, however, TFWiki.net treats RiD!Sideswipe as a separate character from Cybertron!Sideswipe. Willingham himself replaces Fred Tatasciore as Motormaster.
- As noted below, Word of God was ruled that this isn't the case as the Grimlock Khary Payton voices here, isn't the same one that Gregg Berger and Crispin Freeman as Grimlock voiced in War for Cybertron and Fall of Cybertron respectively (Berger did have a role in the series, though, voicing Stockade and Major Mayhem).
- Arif S. Kinchen replaces Scott Whyte and Troy Baker as Jazz. Liam O'Brien also replaced Baker as Kickback (however, as with Sideswipe, TF Wiki considers the two version separate entities). O'Brien was himself replaced as Cyclonus by Harry Lennix.
- Erica Lindbeck voices Windblade in seaaon 3, replacing Kristy Wu.
- Production Posse: Series co-developer Adam Beechen brought over a few of his friends over from Littlest Pet Shop (2012) , those being voice actors Brooke Goldner and Ian James Corlett, writer Guy Toubes, and series developers Julie Mc Nally Cahill and Tim Cahill.
- Promoted Fanboy: Eric Bauza is a fan of Drift, having wanted to voice an incarnation of the character since Transformers Animated. This show gave him his wish.
- Screwed by the Network: Premiered in an abhorrent timeslot (6:30am Saturday mornings), which is bad enough on the East and West Coasts, but what if you're in the Central time zone? That's 5:30 in the morning, a time when absolutely no sane kid (or Transformers fan) would even be awake! Any potential viewer without a DVR, the capability to use Cartoon Network's Video app/website or On Demand platform (both requiring separate participation from a given cable company), the money to spend buying the episodes on iTunes/Amazon, or willingness to outright pirate the show online is pretty much out of luck.
- Fans have accused Cartoon Network of doing this deliberately just so they can air more reruns of the widely-hated Teen Titans Go!; the exact same tactic was used to banish Sonic Boom to an early Saturday morning timeslot as well. A few have even gone as far as to accuse CN of doing so to kill both series and air even MORE TTG reruns.
- Schedule Slip: The third season was stated to premiere in January 2017. It wouldn't air in the US until 29 April 2017.
- Short Run in Peru:
- This series is notable among US-produced Transformers shows in that it premiered virtually everywhere but the US itself first.
- Every episode of the later half of the second season aired in the United Kingdom before their American airdate, with the length of time between UK and US airdates varying between four days to a full month.
- The miniseries featuring Starscream aired in Canada about one to two months before the episodes aired in America.
- Shrug of God: Despite Word of God stating that this Grimlock is not the same Grimlock from previous Aligned entries, the Dinobots are on the blacklist in "Enemy of My Enemy", yet only one Grimlock is shown — the one in Team Bumblebee.
- Spoiled by the Merchandise: The Tiny Titans figurines of Bisk and Quillfire sported the scratched Decepticon insignia of Steeljaw's pack, thus spoiling that they would join the pack in season 2.
- What Could Have Been:
- According to concept work, the character that eventually became Sideswipe was originally conceived as Fastlane. In hindsight, this makes Sideswipe's immaturity and certain other attributes make more sense when compared with other versions of the character.
- Also, Grimlock would have a retracting mouthplate and visor, making him look more like he previously appeared on this continuity.
- The reason for Grimlock's shift in personality from his earlier appearances was because he was originally going to be a new Dinobot character. Hasbro requested that the writers change him to Grimlock in order to cash in on his appearance in Transformers: Age of Extinction. There was an attempt to keep Grimlock's personality and backstory, but it was never implemented due to the clashes of tones between the two series. Producer Adam Beechen later pulled a Decomposite Character on the matter via Word of God and said that the Grimlocks are two different characters.
- Written by Cast Member: A few episodes were written by Will Friedle, the voice of Bumblebee.
Trivia / Transformers: Robots in Disguise