- Awesome, Dear Boy: Leonard Nimoy was very enthusiastic about rejoining the Transformers franchise after having played Galvatron in the 1986 movie.
- Defictionalization: The Wreckers made an appearance in car form during the parade laps of the 2011 Daytona 500
- Deleted Scene: The Twins from Transformers: Revenge of the Fallen were intended to be in this movie but were removed in the final cut. If you look carefully you might be able to see their vehicle modes in a distant line-up shot.
- Doing It for the Art: Bay managed to get the entire city of Chicago to help them with filming the entire climax. Shia LaBeouf and the other cast members were in awe of how much access they had to the whole of the city on a daily basis. Plus the entire wingsuit sequence was put in after Bay saw a TV special on them, and they are actually flying between the skyscrapers wearing portable 3-D camera helmets.
- Name's the Same: Sam and Carly, huh? Even better, Carly's last name is Spencer.
- No Export for You: Hasbro cancelled the American release of the sixth wave of DOTM toys, including the much-anticipated Human Alliance Soundwave, due to low retailer demand. The cancelling of the line also means a Dino/Mirage toy is probably never coming.
- One for the Money; One for the Art: Michael Bay agreed to return as director in order to get Pain and Gain film made.
- The Other Darrin: Sideswipe is voiced by James Remar instead of Andre Sogliuzzo.
- The Other Marty: An unintentional one; Barricade during the torture scene in Chicago speaks with Soundwave's voice as provided by Frank Welker.
- What Could Have Been:
- Due to the released call sheets, it is highly suggested that Sentinel Prime was originally going to be called Ultra Magnus. Test screening however drove the change and Ultra Magnus' head was reused as what the Apollo 11 astronauts step on and uncover as they explore the ship. Considering his actions, this wouldn't be the first time this type of change has happened. note
- The Twins from ROTF were scripted into the movie but were carefully removed from the final cut (you can briefly see their vehicle modes in a line-up shot). Their roles would have been to be killed by Sentinel Prime after he reveals himself as a traitor by killing Ironhide. Maybe they weren't confident in getting an Alas, Poor Scrappy reaction....
- Corey Burton was asked to reprise his role from the original cartoon as Shockwave, but he declined. Before Frank Welker ended up voicing him, David Warner note was also considered for the role.
- Rodimus was intended to appear, concept art of him were made. But he does end up appearing in Transformers: The Last Knight as "Hot Rod".
- Megan Fox was supposed to return but after feuding with Michael Bay she was fired and the character of Carly was created to fill her role.
- James Avery stated he was playing Silverbolt in the film.
- Many of the deaths (and those that survived) were changed, including:
- Megatron being honest of wanting a truce with Optimus and the two parting on good terms, with the Decepticons going to undo the damage they did to Cybertron and Optimus remaining to clean up Earth.
- Que/Wheeljack would have survived the battle
- Dino/Mirage died trying to use his invisibility to escape (something that also was removed)
- The Wreckers were to have a pet robot dog named Steeljaw. Like with Transformers: Revenge of the Fallen, this was cut late in the game and thus a toy was made.
- Word of God:
- They advertised Shockwave as the Big Bad/an important enemy as part of a "misinformation campaign", where they would deliberately lie about certain aspects to keep information and spoilers about the film to a minimum to prevent plot twists having no impact, such as Sentinel Prime being the real Big Bad and Soundwave's car alt-mode.
- Bumblebee's new look is to represent his maturity from a simple guardian to a full-fledged warrior. His stripes are also moved farther out from the center of his vehicle mode.
- The Twins from Transformers: Revenge of the Fallen were killed by Sentinel Prime moments after he destroyed Ironhide but this wasn't included in the theatrical cut for pacing reasons.
Trivia / Transformers: Dark of the Moon