- Talking to Himself: Most of the voice actors (with the exception of Brian Cummings) each voiced two characters;
- Tress MacNeille voices both Momma Moo and Grandma Moo, the latter sounding like Agnes Skinner.
- Jim Cummings voiced both Santa Cow and Dr. Albert Holstein.
- Pat Fraley voices both Grandpa Moo and Chuck Steaker.
- Rob Paulsen voices both T-bone and Chick Bantam, with the former sounding like Gusto Gummi and the latter sounding like Yakko Warner.
- BJ Ward voiced both Patty Moo and Baby Moo.
Trivia / The Moo Family Holiday Hoedown