- Actor Allusion: This isn't the first time Dee Bradley Baker voiced a pet who is also a secret agent.
- Bessie's entire character is this, given that her voice actress played a girl scout with a fondness for honey bees in the first episode of Upright Citizens Brigade. The two character even have the exact same voice and similar names (Bessie and Cassie).
- Channel Hop: The remaining episodes of the series aired on Nicktoons Network.
- Descended Creator: Series co-creator Amy Poehler voices Bessie Higgenbottom
- Keep Circulating the Tapes: The show got only two compilation DVD releases (one of which is a burn-on-demand title from Amazon) and a DVD containing only the first episode on it that was bundled with the DVD release of "Atlantis SquarePantis". Both seasons are on iTunes, at the very least.
- Production Posse: The show is created by Amy Poehler, Cynthia True, and Erik Weise. Amy brought over many people from Saturday Night Live. Cynthia brought over many people from The Fairly OddParents! . Erik brought over many people from SpongeBob SquarePants and The Ren & Stimpy Show.
- Recycled Script: "Dogcatcher in the Rye" is similar to the Rocko's Modern Life episode "Ed Good, Rocko Bad".
- Screwed by the Network: The show got shunted around the schedule shortly after it premiered in 2008, eventually got kicked across to Nicktoons in 2010, and finally had the remainder of the final season burned off in one go during a dead zone afternoon a year later.
Trivia / The Mighty B!