- Actor Allusion: The Gustav brothers' mother (played by Jonathan Winters) is an expy of Winters' famous Maude Frickert character.
- Follow the Leader: For Pee-wee's Playhouse, another children's show based on an adult-child character from an adult-oriented comedy sketch.
- Harpo Does Something Funny: All of the live-action segments are clearly improvised.
- Shown Their Work: Despite being the typical No Budget production for which Hanna-Barbera was known, Ed's body language is astonishingly accurate to how Martin Short performs him.
Trivia / The Completely Mental Misadventures of Ed Grimley