- Referenced by...: In Twelve Days, Madame Gupta tells Terry, "Beauty is mysterious as well as terrible. A lady must have her secrets." Terry says, "The full quote is, 'Beauty is mysterious as well as terrible. God and devil are fighting there, and the battlefield is the heart of man.' That's from The Brothers Karamazov. Read it."
- The character of Fyodor Karamazov in Warhammer 40,000 is one giant, screaming parody of "The Grand Inquisitor" segment of this work; he works for the Imperial Inquisition, is considered overzealous and brutal by the standards of the Inqusistion, and he has a very frosty relationship bordering on hatred of the Ecclesiarchy (the state church of the Imperium of Man that is separate from the Inqusition) for an incident where he tried and executed a possible candidate for the reincarnation of the God-Emperor of Mankind, in much the same way that The Grand Inqusitor castigated a reborn Jesus in this work.
- What Could Have Been: The novel was intended to be only the first arc of a much larger story, entitled The Life of a Great Sinner, but Dostoevsky died before he could complete any more of it (four months after the novel's publication, in fact).
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