- Creator Backlash: While writer Richard Pursel still loves "Ren Seeks Help", he has made it clear that he does not like the parts with the brutally abused and suicidal frog, which were added into the episode by John K despite him being strongly against it and vocal about it.
- Meta Casting: John Kricfalusi (Ren) cast his father Michael to voice Ren's father in this episode.
- What Could Have Been: This episode was originally written in 1991 during the original series's run. For better or worse, it was saved for the Adult Party Cartoon.
- Writer Revolt: John K. and Richard Pursel conceived the episode out of their frustrated believe that there were only a handful of TV episode concepts that had simply been repeated over and over. A Zany Cartoon character going to therapy was the only thing they could think of that had never been done before.
- Write Who You Know: Ren's father is a combination of John K's own stern father (who voices the character) and his Unitarian minister grandfather.
Trivia / Ren & Stimpy "Adult Party Cartoon" E2 "Ren Seeks Help"