- Actor Allusion: Kaz Kaan's life is a lot like how Jaden Smith's might be, complete with odd philosophical dialogue.
- Celebrity Voice Actor: Featuring Jaden Smith, Jude Law, Susan Sarandon, Steve Buscemi, and many others.
- Defictionalization: One YouTuber put together some Gregorian House tracks based on episode 3.
- The Danza: In the Christmas Special, Angélique Kidjo as Aunt Angelique.
- Network to the Rescue: It was originally planned to be aired on Fox's Animation Domination High-Definition block circa 2015 or 2016, but the block wound up shutting down before the show had a chance to air. It was later picked up by Netflix.
- Playing Against Type:
- In the Mexican Spanish dub, Charles is voiced by René García, a voice actor normally typecasted voicing hot-blooded badasses, jerks, or the smart guy.
- The same goes in the Japanese dub with the same character and his voice actor, Yasuhiro Mamiya, who is normally typecasted with voicing villainous roles or The Big Guy.
- The Wiki Rule: The Neo Yokio Wiki.
Trivia / Neo Yokio