- Acting for Two:
- The Other Darrin:
- In the original Japanese version:
- In the English dub:
- Brittney Karbowski replaced Kate Bristol as the English voice of Anya, even though Bristol returned to voice Sayo.
- J. Michael Tatum replaced Troy Baker as the voice of Nagi due to the latter doing union-only voice work in Los Angeles.
- R. Bruce Elliott replaced Randy Tallman as Konoemon due to Tallman's death.
- Cherami Leigh provided the voices for Setsuna Sakurazaki and Akira Okouchi this time around. Leigh also subbed for Alison Viktorin's roles of the Narutaki sisters due to the latter's maternal leave.
- Carrie Savage replaced as Jayme Westman as Satomi Hakase.
- Mary Morgan replaced Susan Huber (Lucy Small) as Madoka Kugimiya.
- Studio Hop: Though TV Tokyo was still involved as a broadcaster, Gansis and Studio Shaft handled the animation instead of Xebec.
- The Wiki Rule: The Negima! Wiki.
Trivia / Negima!?