- The Other Darrin: Due to the anime being licensed by Sentai Filmworks and their tighter schedule and lower budget, Kira Buckland, who voices Anne in Shadowverse, did not reprise her role (the role was casted to Cat Thomas instead).
- Relationship Voice Actor: Nana Mizuki (Hanna), Kimiko Koyama (Lou) and Kikuko Inoue (Miranda) were Moka, Yukari and miss Nekonome in Rosario + Vampire, performing similar roles to the ones they do in Mysteria friends (the two former being students, while the later being a teacher with a ditzy personality).
- What Could Have Been: Judging by the original trailer, Mysteria Friends was originally planned to be a more straightforward adaptation of Rage of Bahamut's "Mysteria Academy" event (which also has a number of similarities to the "Lonesome Dragoness" event of Granblue Fantasy), with more of a plot focus and much more action. Sometime between the project being postponed and its re-announcement it was reworked into the much more Slice of Life-focused anime that was ultimately released.
Trivia / Mysteria Friends