- Beam Me Up, Scotty!: Despite what some parodies would have you believe, the Mysterious Man never says "I'm in your house". The real dialogue is as follows:Mysterious Man: We've met before.
Frank: I don't think we have. Where have we met?
Mysterious Man: At your house, don't you remember? In fact... I'm there right now.
Mysterious Man: In your house.
- Box Office Bomb: Budget, $15 million. Box office, $3.7 million. Never left limited release as it was only released in 337 theaters across North America. Once it hit HBO it started to find its audience.
- Creator Backlash: Though David Lynch hasn't outright disowned the film (à la Dune), he's since elaborated that he made the film during a difficult time in his life, namely a divorce and witnessing the apparent ripping-off of his work by directors like Oliver Stone, and the film's dour and often dour tone reflected this.
- He ended up disowning the initial American Blu-Ray release of the film from Kino Lorber since it was made using old elements and not the final negative.
- Deleted Scene:
- A scene where a medical examiner brings two girls to the autopsy of Renee's corpse, and chats with them about the murder.
- Additional scenes of Fred in prison.
- A scene in which Pete stands in front of his parents, but they are unable to see him.
- A scene in which Pete cannot be seen by Sheila, his girlfriend.
- Dyeing for Your Art: Bill Pullman didn't know how to play the saxophone, so he spent several weeks learning how to play the specific solo featured in the film.
- In Memoriam: Lynch regular Jack Nance died a month before the film was released.
- Playing Against Type: Gary Busey as Pete's dad, who seems like a genuinely kind and not-creepy man.
- Throw It In!: Robert Loggia kept forgetting his choreography during his fight scene with Bill Pullman, leading to the two accidentally and repeatedly hitting each other.
- What Could Have Been: The song accompanying Fred and Renee's sex scene, "Song of the Siren" by This Mortal Coil, was originally intended for use in Blue Velvet, but the filmmakers were unable to get the rights for it at the time.
- Word of God: Lynch has acknowledged the trial of O.J. Simpson as an influence on the film.
- Write What You Know: The opening scene in the film is based upon an incident that occured to Lynch in real-life. He says that early one morning, his intercom buzzed, and when he answered it a voice he didn't recognize said, "Dick Laurant is dead." However, by the time he got to the front of the house to look out the window, there was no one outside.
- Written-In Infirmity: Richard Pryor was confined to a wheelchair due to multiple sclerosis.
Trivia / Lost Highway