- Actor Allusion:
- Ashley Argota portrays an enemy to Kelli Berglund's character, just like in How to Build a Better Boy.note
- In Under Siege, this isn't the first time Jeremy Kent Jackson's character had to contend with the protagonist's malfunctioning arm.
- The beach episode of the show is called "Dude, Where's My Lab?" a reference to Dude, Where's My Car? which Hal Sparks appeared in. It's also a pun recycled from Kickin' It. In an ironic coincidence, on Netflix "Dude, Where's My Sword?" is mislabeled as "The Wrath of Swan" and vice versa — and "The Wrath of Swan" was the episode that Billy Unger guest-starred on.
- Troy obsessing over his hair is a character trait he shares with Jack, who was also portayed by Leo Howard.
- Leo isn't Tyrel Jackson Williams' only role as a Deadpan Snarker.
- Adored by the Network
- Billing Displacement: Billy Unger is billed first in the opening, when really, it's Leo who's the protagonist, yet he's listed under the And Starring title.
- The Cast Showoff: Billy Unger is a skilled martial artist himself so it's not a shock to see his character Chase pull off amazing martial arts moves shown in episodes like Bionic Birthday Fail and Quarantined.
- Dawson Casting: Bree and Chase are roughly the age of the actors playing them, Bree might be 15 and Kelli Berglund is 16. It's also stated that Bree is older than Chase, although Kelli Berglund is a few months younger than Billy Unger. However, Spencer Boldman became 20 before the 1st season has done airing and Adam is either 16 or 17.
- Directed by Cast Member: Hal Sparks directed 4 episodes, one in Season 3 and three in Season 4, one of which he doesn't appear in ("Spider Island"). Additionally Jerry Russo directed "Perry 2.0".
- Hide Your Pregnancy : Angel Parker, who plays Tasha, was pregnant with her second child towards the end of shooting the first season.
- Meaningful Release Date: "Air Leo" premiered on October 8, 2012, the night of the series premiere of Crash & Bernstein. To tie into the show's premiere, both Lab Rats and Kickin' It ("Wedding Crashers") had Crash and Bernstein star Oana Gregory (Amanda) make guest appearances that night.
- Missing Episode: One can wonder where Rise of the Secret Soldiers went
- Name's the Same: There's another show that features a pair of twin brothers named Donald and Douglas.
- New Season, New Title: With Season 4 and the subtitle Bionic Island.
- Real-Life Relative: In one episode, Leo's future-self is played by his Real Life older brother Tyler James Williams.
- What Could Have Been: Originally, the main characters would be Adam and Brad (now Chase), robots who worked for the government, but escape to live like humans after knowing they would be demolished. This version also wouldn't have Bree. The part where they work for the government has at least been saved for Season 3, after their secret has been revealed.
- Working Title: Billion Dollar Freshman.
Trivia / Lab Rats